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Tiny bone holes may help adults avoid jaw surgery

NCT ID NCT06467240

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study tested a special dental expander combined with tiny bone perforations (MOPs) to widen the upper jaw in 14 adults aged 17-23 with a narrow jaw and crossbite. The goal was to see if this less invasive method could effectively expand the jaw without major surgery. Results are based on CT scans to measure how much the bone and teeth moved.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
hybrid rapid maxillary expander assisted with micro-osteoperforation (MOPs)
What this could lead to
If successful, this approach could offer a less invasive way to correct a narrow upper jaw in adults without surgery.
What could go wrong
This was a very small study with only 14 participants, so results may not apply to everyone. The procedure involves drilling tiny holes in the bone, which carries risks like pain, swelling, or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

14 people

The number who actually took part.

Started

Oct 2024

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

randamly selected

Ages

17 to 23 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * An age range from 17-23 years. * Transverse maxillary deficiency. * Maxillary lingual Cross bite (unilateral or bilateral) * No history of previous orthodontic treatment. * Good oral and general health. * No systemic condition that could interfere with orthodontic treatment. Exclusion Criteria: * Patient with craniofacial anomalies . * History of extraction of permanent teeth. * Previous orthodontic treatment. * Poor oral hygiene or periodontally compromised patient. * Previous history of bruxism, trauma or par functions.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dental Medicine Al-Azhar University

    Cairo, Naser City, 4450113, Egypt