Al-azhar University

This study tests a new effervescent (fizzing) powder containing 5-fluorouracil to treat vitiligo, a condition that causes white patches on the skin. Sixty people with stable vitiligo will apply either the new fizzing powder or plain 5-fluorouracil powder to their patches. The goa…

This study tests whether using an 810 nm diode laser during root canal retreatment helps the bone around the tooth heal better. Forty adults with a failed root canal and a visible infection will receive standard retreatment plus either laser disinfection or a calcium hydroxide pa…

This study tests whether giving ozone gas through the rectum can protect the brain and reduce damage in children who have suffered a brain injury from events like trauma, infection, or lack of oxygen. About 120 children aged 1 month to 18 years in the pediatric ICU will receive t…

This study looks at whether adding echinacea (Immulant®) to standard care can reduce symptoms and parasite levels in children aged 5–12 with weakened immune systems who have cryptosporidiosis, a diarrheal infection. About 60 children will take part. The goal is to see if the supp…

This study tests a new paste made from zinc oxide and ginger (6-gingerol) against a standard antibiotic paste for treating infected baby molars in children aged 4 to 8. The goal is to control the infection and save the tooth until it naturally falls out. Researchers will measure …

This study tests two nano-sized medications placed inside the tooth to control infection and inflammation after a root canal has failed. About 63 adults with a persistent tooth infection will receive either nano-calcium hydroxide or nano-chitosan. The goal is to see which better …

This study tests whether coating a dental implant with erythropoietin gel helps it bond more firmly with the jawbone. Twenty-four adults needing a front tooth implant will be randomly assigned to get either a gel-coated or standard implant. The main goal is to measure implant sta…

This study tests two mouthwashes—one with probiotics (good bacteria) and one with ethyl lauroyl arginate—to see which better reduces cavity-causing bacteria, plaque, and acidity in the mouths of Egyptian children aged 6 to 12. Researchers will measure bacteria levels and plaque b…

This study tests whether silver-hydroxyapatite nano-coated miniscrews work better than uncoated ones for moving the upper front teeth backward as a single unit. Fourteen teens aged 14-20 with Class I malocclusion and bimaxillary protrusion will be enrolled. The goal is to see if …

This study tests whether a natural sleep hormone, melatonin, can reduce anxiety in children before surgery. About 120 kids aged 4 to 14 will receive either a low dose, a higher dose, or a placebo pill 90 minutes before anesthesia. The goal is to see if melatonin works as well as …

This study compares two types of dental files used during root canal treatment to see which one causes less pain during and after the procedure. 56 adults with infected upper premolars will be randomly assigned to receive treatment with either a reciprocating or a rotary file sys…

This study looks at two methods of giving a pain-relieving injection (called a TAP block) after a planned C-section. One method uses ultrasound to guide the needle, the other is done by the surgeon during the operation. The goal is to see which approach provides better pain contr…

This study tests whether adding dexmedetomidine or tramadol to standard paracetamol can reduce bladder discomfort caused by urinary catheters after kidney stone surgery. About 60 adults aged 20–50 will be randomly assigned to one of three groups. The goal is to find a better way …

This study tests whether giving vitamin D3 locally and using a minor surgical technique called corticision can make orthodontic tooth movement faster. Sixteen patients aged 13-20 who need premolar extractions will be followed for 12 weeks. The goal is to see if these methods safe…

This study looks at whether applying vitamin C directly to the gums can safely reduce dark spots caused by natural pigmentation. Thirty adults with dark gums will receive vitamin C as a gel, with tiny needles (microneedling), or as injections (mesotherapy). The goal is to see whi…

This study looks at whether giving melatonin under the tongue before cataract surgery can reduce anxiety and help older adults relax. Sixty people aged 60 and older will receive either melatonin or a placebo. The goal is to find a safer alternative to standard sedatives that may …

This study tests three different ways to prevent pain from a tourniquet (a tight band that stops blood flow) during forearm surgery. Sixty adults having forearm surgery will be randomly assigned to receive one of three pain-blocking methods. The goal is to find which method works…

This study tests whether using a special laser along with standard ultrasonic cleaning can reduce pain and kill more bacteria after a root canal. About 120 adults with infected single-root teeth will be treated and asked to rate their pain. The goal is to find a better way to man…

This study tests if making small holes in the jawbone (micro-osteoperforations) helps move front teeth more safely and effectively in people with a deep bite. 18 participants aged 15-25 will receive standard braces with or without the extra procedure. The goal is to see if it red…

This study tests if using a special laser to clean the tooth after a second root canal can lower pain and inflammation. About 52 adults with a failed first root canal and an infection at the tooth tip will be treated. The laser is used along with standard cleaning to see if it he…

This study looks at how well therapeutic plasma exchange (a blood-filtering procedure) works for people with autoimmune neurological diseases. Researchers at Al-Azhar University Hospitals will follow 60 Egyptian patients to see if their symptoms and daily function improve. The go…

This study looks at how two types of dental crowns—stainless steel and bioflex—affect oral hygiene and bacteria levels in children aged 4 to 8. Researchers will measure plaque and gum health after placing crowns on baby molars. The goal is to see which crown type leads to a clean…

This study looks at how changing the air pressure in a patient's lungs during a tummy tuck (abdominoplasty) affects their breathing after surgery. Researchers will measure lung pressure before and after the surgeon tightens the belly muscles, and then check lung function afterwar…

This study observes 100 adults aged 20–40 who are having nose surgery (septorhinoplasty) to see if the length of time nasal packing is left in place affects the development of sore throat or pharyngitis. Participants will have their sore throat, swallowing difficulty, and throat …

This study looks at 20 adults with hearing loss in one ear but a normal-looking eardrum. Doctors want to see how often their best guess about the cause matches what they find during a small ear surgery. The goal is to improve diagnosis and treatment for this tricky condition.