Mouthwash showdown: probiotics vs. arginate for healthier smiles
NCT ID NCT07356869
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests two mouthwashes—one with probiotics (good bacteria) and one with ethyl lauroyl arginate—to see which better reduces cavity-causing bacteria, plaque, and acidity in the mouths of Egyptian children aged 6 to 12. Researchers will measure bacteria levels and plaque buildup before and after 28 days of use. The goal is to find a simple, effective way to improve children's dental health.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 66 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2025
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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6 to 12 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy Egyptian schoolchildren aged 6-12 years. * Good general health. * Mild to moderate dental plaque accumulation. * Parental/caregiver willingness to provide consent Exclusion Criteria: * Antibiotic or antimicrobial use within the last month. * Allergies to the mouthwash components. * Systemic diseases affecting oral health. * Orthodontic appliances or extensive dental restorations.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Al-Azhar University (Faculty of Dentistry)
RECRUITINGCairo, 11651, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can natural mouthwashes fight cavity bacteria as well as chlorhexidine?
- Can a Protein-Packed toothpaste outperform fluoride alone?
- Can a local anesthetic injection curb Kids' pain after tonsil removal?
- Dead probiotic bacteria put to the test in Kids' saliva
- Two ways to rebuild a Child's bone: which holds up?
- Which mouthwash fights plaque better: chlorhexidine or essential oils?