Vitamin d injection may shorten braces time, small study hints
NCT ID NCT07455656
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving vitamin D3 locally and using a minor surgical technique called corticision can make orthodontic tooth movement faster. Sixteen patients aged 13-20 who need premolar extractions will be followed for 12 weeks. The goal is to see if these methods safely speed up canine retraction and improve bone density.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 16 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2025
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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13 to 20 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: 1. Orthodontic patients referred for therapeutic extraction of bilateral maxillary first premolars (Angle Class II division 1 cases, with crowding and bimaxillary protrusion). 2. Fully erupted permanent teeth (except third molar). 3. Age 13-20 patients. 4. No previous orthodontic treatment. 5. Good oral and general health. 6. No systemic disease or regular medication that could interfere with and/or affect orthodontic teeth movement. Exclusion criteria: 1. Patients with impacted canines. 2. Patients with severe crowding. 3. Patients with untreated decay or any endodontic lesions. 4. Patients with thyroid, parathyroid, or renal and liver disease.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Orthodontic Outpatient Clinic, Faculty of Dental Medicine, Al-Azhar University
RECRUITINGCairo, Cairo Governorate, 11651, Egypt
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