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Can a tiny bone cut shorten your time in braces?

NCT ID NCT07752212

Disease control Sponsor: Foundation University Islamabad Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 07, 2026 · Last updated Aug 12, 2026 · Updated 2 times

Summary

This trial tests whether a minor surgical procedure called piezocision can speed up the movement of canine teeth after premolar extraction, potentially shortening orthodontic treatment. In a split-mouth design, each participant receives piezocision on one side of the mouth and conventional retraction on the other, allowing direct comparison. The study measures how much the canines move over 12 weeks. If piezocision proves faster, it could reduce the overall time needed for braces.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Piezocision, a minimally invasive surgical procedure using a piezoelectric knife to make small incisions in the gum and bone to potentially speed up tooth movement.
What this could lead to
If effective, piezocision could shorten orthodontic treatment time by accelerating canine retraction, reducing the duration of braces.
What could go wrong
This is a small, early-stage trial (30 patients) and results may not apply broadly. The procedure is invasive and carries risks like swelling, discomfort, or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Jul 2022

Finished

Jul 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

15 to 35 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients between the age of 15-35 years * Both male and female patients * Treatment plan with extraction of maxillary first premolars or both maxillary and mandibular first premolars. * Space for canine retraction of at least 3mm after levelling and alignment Exclusion Criteria: * Craniofacial syndromes * Previous Orthodontic treatment * Systemic disease * Periodontal bone loss

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Canine retraction Piezocision

Contacts and locations

Locations

  • Foundation University College of Dentistry and Hospital

    Islamabad, Federal, 44000, Pakistan

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