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Diabetes drug may boost dental implant success, small study finds

NCT ID NCT07469254

Disease control Sponsor: Al-Azhar University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether adding 1% metformin gel to a bone graft improves bone healing and implant stability in people getting immediate dental implants. Twenty adults aged 18 to 40 with a non-restorable tooth in the front or premolar area took part. The researchers measured implant stability and gum health over 12 months to see if the gel made a difference.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Nov 2022

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age from 18 to 40 years. * Both sexes. * Adult individual with non-restorable tooth in esthetic and premolars area and seeking for immediate implant placement. * Systemically healthy patients were selected for implant surgery according to the criteria of Cornell medical index and its modifications. * The recipient site of the implant should be free from any pathological conditions. * Sufficient vertical bone height to safely place at least 12 mm long dental implant. Exclusion Criteria: * Smokers. * Pregnant or lactating female patients. * Patients with parafunctional habits such as bruxism and clenching. * Presence of acute infection around the failing tooth. * Perforation and/or loss of the labial bony plate following tooth removal and/or implant osteotomy. * Inability to attain primary implant stability following immediate implant placement.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bone graft Immediate dental implants Metformin gel

Contacts and locations

Locations

  • Al-Azhar University (Assiut)

    Asyut, 71524, Egypt

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