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Can a collagen patch improve gum healing after dental bone grafts?

NCT ID NCT06871735

Disease control Sponsor: Ohio State University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether placing a special collagen material over an exposed barrier membrane helps gum wounds heal better after guided bone regeneration (GBR) for dental implants. About 30 people who already need GBR will be observed; if the membrane is exposed, the surgeon may use the collagen patch. Researchers will compare healing and success rates between those who get the patch and those who don't.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
acellular collagen matrix (Mucograft)
What this could lead to
If it works, this could give dentists a reliable way to help gum wounds heal after bone grafting, improving the success of dental implants.
What could go wrong
This is a small, early study with only 30 people, so results may not apply to everyone. The material is already used in practice, but the study is just observing outcomes, not proving a cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2023

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants are patients at the Graduate Periodontics Clinic at The Ohio State University College of Dentistry who have been treatment-planned for a guided bone regeneration procedure prior to dental implant.

Ages

21 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Have a missing tooth or teeth which are planned to be replaced with an implant * Need for guided bone regeneration procedure to increase the bone available for implant placement * Systemically healthy with no contraindications for bone grafting and/or implant surgery * No chronic sinus problems * Non-smoker * No need for removable temporary restorations during wound healing. Exclusion Criteria: * Patients that have sufficient bone volume to perform implant placement through conventional drilling protocol without any pre-implant GBR procedure * Indications for pre-implant/pre-GBR soft tissue grafting procedure to increase existing soft tissue contours * The need to wear a removable temporary restoration during healing

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bone graft

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • The Ohio State University Graduate Periodontics Clinic

    RECRUITING

    Columbus, Ohio, 43210, United States

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