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New bone graft blend could improve dental implant success

NCT ID NCT06275789

Disease control Sponsor: Nova Southeastern University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study compares a new mixture of two bone graft materials to a standard one for preserving the jawbone after a tooth is pulled. Thirty healthy adults who need a premolar or molar extracted and plan to get a dental implant will receive the new graft. Researchers will measure changes in bone width and height over 4 months and check bone quality under a microscope.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bone graft material (mix of demineralized freeze-dried bone allograft and deproteinized bovine bone mineral)
What this could lead to
If successful, this could provide a better option for preserving jawbone shape and density after tooth extraction, improving future implant success.
What could go wrong
This is a small, early-phase study with only 30 participants, so results may not apply to everyone. The new graft mix may not outperform the standard material.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2024

Expected to finish

Jun 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients in good health * Require the extraction of at least one premolar or molar with future implant placement * Sufficient keratinized gingiva (equal or more than 2mm prior to extraction), * No more than 3mm of buccal bone loss * Flapless extraction possible * Full mouth plaque index of less than 25% Exclusion Criteria: * Nicotine consumption equivalent to or more than 10 cigarettes per day * Electronic cigarette usage * A history of irradiation of head and neck area * Immunodeficiency disease * Uncontrolled systemic health problems (hypertension crisis 180/120, hyperthyroidism, diabetes with HbA1c over 7, recent history of stroke, cancer) History of medications that affect bone remodeling process (bisphosphonates, RANK-L inhibitors) * Previous adverse reaction to the biomaterials used * Pregnancy/lactation, or those who are trying to become pregnant. * Active uncontrolled or untreated periodontal disease * Periapical lesions greater than 1 cm and soft tissue pathology

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alveolar ridge preservation Bone graft Dental extraction

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Nova Southeastern University

    RECRUITING

    Fort Lauderdale, Florida, 33328, United States

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