SUICIDE

This study looks at whether a longer course of talk therapy helps Veterans who have been hospitalized for suicide risk. About 136 Veterans will be randomly assigned to one of two therapy programs and followed for a year. Researchers will also use brain scans to see if changes in …

This study is testing a 6-month, remote support program called Pathfinding for active-duty soldiers who have just left a psychiatric hospital. The goal is to see if this extra help, on top of usual care, can reduce suicide attempts and related behaviors. About 1,500 soldiers acro…

This study tests a smartphone app with game-like features to help people with mental disorders after they leave the hospital. The goal is to reduce suicidal thoughts and encourage follow-up visits. The study will include 640 adults in Shenzhen, China, and their lay health support…

This study tests a short problem-solving therapy to prevent suicide in adults aged 50 and older who have suicidal thoughts. Participants will receive the therapy in person, by phone, or through a smartphone app, and be compared to those getting usual care. The goal is to see if t…

This study is testing a 90-day support program called 'Caring Connections' designed to prevent suicide in high-risk teenagers. The program connects teens with mental health services, helps create safety plans, and builds a network of community support, often through faith-based o…

This study tests whether a type of talk therapy, delivered via video call, can reduce suicidal thoughts and attempts in adults with physical disabilities (vision, hearing, or mobility issues). Researchers will enroll 60 people who have had recent suicidal thoughts or a recent sui…

This study tests a 90-day program called Caring Connections that helps high-risk youth (ages 13-19) who have thoughts of suicide or have attempted suicide. The program provides support, safety planning, and connections to mental health services. Researchers will compare this prog…

This study tests a 12-week therapy called Integrated Suicide and Trauma Therapy (ISTT) for adults who had childhood trauma and are currently thinking about suicide. The therapy combines coping skills training with trauma-focused care to reduce suicidal thoughts. The study involve…

This study is testing a new short-term treatment called Suicidal Crisis Intervention (SCI) to help adults who have attempted suicide or are in a suicidal crisis. The goal is to reduce suicidal thoughts and related feelings like hopelessness. About 390 participants will be randoml…

This study tests whether a new drug called (2R,6R)-HNK can quickly improve symptoms in adults with major depression that hasn't responded to other treatments. About 50 participants will receive four infusions of the drug and four of a placebo over several weeks, with their mood a…

This study tests whether adding ketamine to an online therapy program can quickly reduce suicidal thoughts in people with depression that hasn't improved with other treatments. About 110 adults will receive weekly online therapy for 13 weeks, and half will also get six ketamine i…

This study tests whether a single intensive therapy session called Brief Skills for Safer Living can reduce suicidal thoughts in adults. 150 participants across Canada will be randomly assigned to receive the therapy right away or after a 3-month wait. The goal is to see if this …

This pilot study tests a mobile app called MIST designed to help veterans change negative thought patterns linked to suicide. About 50 veterans with recent suicidal thoughts will use the app alongside their usual care. The goal is to see if the app is easy to use and helpful, not…

This study aims to reduce suicide among sexual and gender diverse young adults aged 18-24. It compares two brief suicide prevention programs adapted for this group, delivered via telehealth in primary care clinics. About 1,485 participants who screen positive for suicide risk but…

This study tests two self-guided online therapy courses for veterans who have depression or have had suicidal thoughts. About 472 veterans from several states will try one of the courses and report how helpful it is. The goal is to see if these online tools can reduce symptoms an…

This study tests whether a single low dose of ketamine, given in the emergency department, is safe and practical for adults (ages 18-65) who are having serious suicidal thoughts. Researchers will monitor side effects and ask staff about their experience. The goal is to see if ket…

This study tests a program called Friendship Bench + Safety Planning to see if it can reduce suicidal thoughts and behaviors in teenagers living with HIV. About 60 teens aged 13-19 in Lilongwe, Malawi will either get this program or standard care. The goal is to see if the progra…

This study tests two short, proven therapies for young people ages 12-24 who are at risk for suicide and visiting emergency rooms. One approach helps youth create a safety plan and get follow-up calls, while the other teaches skills to handle relationship problems that can lead t…

This study compares two proven emergency care methods for teens and young adults (ages 13-24) who come to the ER with suicidal thoughts or actions. The goal is to see which approach better prevents suicide attempts and helps them start mental health treatment. Researchers will fo…

This study is testing a virtual reality (VR) program for teens ages 13-18 who are in the hospital for suicidal thoughts or behaviors. The VR program lets them practice school and social situations in a safe, guided environment. The goal is to see if the program is easy to use and…

This study tests whether a smartphone app featuring recovery stories from other teens can help reduce suicidal thoughts in at-risk adolescents. About 46 teens from The Bronx who have had recent suicidal thoughts and depression will use the app for a short time. The goal is to see…

This study is testing a combination of two treatments for Black teenagers (ages 12-17) who are at risk for suicide. The treatments are a type of therapy called Cognitive Behavioral Therapy for Suicide Prevention (CBT-SP) and a program where the teen chooses up to 5 caring adults …

This study looks at how to help Suicide Intervention Officers in the Connecticut Army National Guard. These officers are trained to spot soldiers in crisis and connect them with help, but they often lack support themselves. Researchers will test ways to support these officers and…

This study follows 500 adults with depression, bipolar disorder, or suicide risk who are already receiving care. Researchers will use interviews, questionnaires, and optional tests like blood draws and brain scans to track how symptoms change over time. The goal is to find better…

This study works with 20 prison staff and 20 people in detention to improve three suicide prevention tools for use in jail settings. Through interviews, researchers will learn what works, what doesn't, and how to adapt these tools to the realities of prison life. The goal is to m…

This study is testing whether offering follow-up calls to people who call a suicide helpline in Flanders, Belgium, is helpful and practical. About 98 adults who call due to suicidal thoughts will be offered callback conversations. Researchers will interview callers and helpline s…

This study is testing a digital platform that uses smartphone data (like activity and sleep patterns) to help therapists better support teens at high risk for suicide. About 78 teens aged 13-18 who are already in a treatment program will use the platform alongside their usual car…

This study looks at whether trained peer support specialists can help LGBTQ+ youth (ages 12-17) who are involved with juvenile justice, child welfare, or mental health services and have thoughts of suicide or self-harm. The goal is to see if this approach is practical and helps w…

This study tests whether sending supportive text messages to parents of teens who visited the ER for suicide risk can help prevent future suicide attempts and reduce parent stress. About 420 parent-teen pairs will take part. The goal is to see if this simple, low-cost approach ma…

This study tests a short therapy program (ASSIP-OA) designed to prevent suicide in adults aged 65 and older who have recently attempted suicide or had serious suicidal thoughts. About 132 participants will receive either the program plus usual care or usual care alone. Researcher…

This study looks at how teenagers with a history of self-harm learn and use two specific coping skills in daily life. About 200 teens and a parent will practice these skills during discussions while their heart rate and sweat are measured. Some will also get brain scans. The goal…

This study is testing whether a set of suicide prevention strategies can work in primary care clinics in rural Nepal. About 147 healthcare workers and patients will take part. The goal is to see if the program is practical and well-liked, so it can be tested in a larger study lat…

This study tests whether brief smartphone messages, sent when a person reports suicidal thoughts, can help them use their safety plan and lower their immediate risk. About 185 adults hospitalized for suicidal thoughts will answer surveys up to 4 times daily and may receive a tail…

This study is testing a mobile app designed to reduce the stigma around suicide and increase knowledge about it. The goal is to help people feel more comfortable seeking help. About 214 adults in Spain will use the app and report their experiences. The study does not provide trea…

This study is testing a program that helps school health clinics in rural West Virginia regularly screen teenagers for suicide risk. Researchers will work with providers, parents, and teens to adapt the program to fit local needs. About 30 youth will take part to see if the scree…

This study looks at 300 people with mood disorders to find out what makes someone more likely to think about or attempt suicide. Researchers will use questionnaires and blood/urine tests to understand biological, psychological, and social factors. The goal is to create a tool tha…

This study is creating and testing a new group therapy for veterans who have recently had a suicidal episode. The therapy, called Continuous Identity-Cognitive Therapy (CI-CT), focuses on helping veterans rebuild hope, self-identity, and relationships. About 57 veterans will help…

This study looks at how the daily rhythm of sleep and social activity relates to mood and suicidal thoughts in older adults who recently lost a spouse or life partner. Researchers will track 169 participants over 12 months using surveys and activity monitors. The goal is to under…