Can a brief ER talk save young lives? major study tests two suicide prevention strategies
NCT ID NCT06151158
First seen Jun 27, 2026 · Last updated Jul 09, 2026 · Updated 2 times
Summary
This study aims to find the best way to prevent suicide in young people ages 12-24 who are at high risk. Researchers will compare two short, proven crisis interventions given in emergency rooms: one focuses on creating a safety plan and follow-up calls, while the other teaches skills to handle relationship problems that can lead to suicidal thoughts. The goal is to see which approach better reduces suicidal thoughts and attempts, and to improve care for diverse youth in five U.S. cities.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 484 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2025
- Expected to finish
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Aug 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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12 to 24 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Suicide Risk During Acute Care Visit (At least one item in risk assessment is required; check all that apply): \_\_\_ Chief complaint of suicide-related concern (via Medical Record/Other), \_\_\_ Active suicidal ideation endorsed in past 1 month on validated suicide screener, \_\_\_ Suicidal behavior in the past 3 months on validated suicide screener, \_\_\_ Clinician indicated SI in past month or SA in past 3 months. * Have access to a cellular phone with the ability to receive phone calls and text messages over the 12-month follow- up period * Adolescent must be verbally fluent and can communicate, understand, and read in either English or Spanish * Adolescent has been/will be discharged from a higher level of care (i.e. inpatient, day hospital, partial hospitalization program (PHP), or residential treatment program) and back in the community within 4 weeks of their acute care visit. \[Note: this criterion does not apply to all patients - select N/A if this is the case. Exclusion Criteria: * Significant cognitive or developmental delays that prevent understanding or using SPI+ or IPT-A-SCI (includes inability to communicate verbally) * Altered mental status (acute psychosis, intoxication, or mania) * Unable or unwilling to provide informed consent (adults), assent (minors), or permission (parents/caregivers) * The services offered through the study are not in the best clinical interest of the patient (e.g., presenting problem requires a different level of care or treatment approach).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
6 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Childrens Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Columbia University Irving Medical Center (CUMC)
RECRUITINGNew York, New York, 10032, United States
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Johns Hopkins All Children's Hospital
RECRUITINGSt. Petersburg, Florida, 33701, United States
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Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21205, United States
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University of North Carolina Medical Center
RECRUITINGChapel Hill, North Carolina, 27514, United States
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Weill-Cornell Medicine
RECRUITINGNew York, New York, 10065, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Five-Minute talk about gun storage save lives?
- Can music soothe the inner pain of a suicidal crisis?
- Can schools catch teen mental health struggles before they escalate?
- Can a 60-Minute group session and peer calls curb suicide crises?
- Can a centralized team prevent more suicide attempts?
- Talking it out: could Village-Led chats curb youth suicide?