SMOKING
Clinical trials for SMOKING explained in plain language.
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E-Cigs tested as a safer alternative for asthmatic smokers
Disease control CompletedThis study looked at whether giving electronic cigarettes (e-cigarettes) to adults with asthma who smoke regular cigarettes could help them cut down on smoking and improve their lung health. Seventeen people took part, and researchers measured changes in how many cigarettes they …
Matched conditions: SMOKING
Phase: NA • Sponsor: Brown University • Aim: Disease control
Last updated May 26, 2026 08:44 UTC
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New wellness program aims to help HIV-Positive veterans kick the habit
Disease control CompletedThis study tested a special wellness program designed to help veterans living with HIV quit smoking. 234 veterans who smoked at least 5 cigarettes a day took part. The program was compared to standard care, which included a quitline and text messaging support. The goal was to see…
Matched conditions: SMOKING
Phase: NA • Sponsor: Seattle Institute for Biomedical and Clinical Research • Aim: Disease control
Last updated May 26, 2026 08:43 UTC
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New study aims to clear the air in public housing by helping smokers quit or cut back
Disease control CompletedThis study tested two approaches to help people in public housing buildings follow smoke-free rules and reduce secondhand smoke. One approach encouraged all residents to support the policy, while the other focused on helping smokers cut back or quit. About 405 residents took part…
Matched conditions: SMOKING
Phase: NA • Sponsor: Columbia University • Aim: Disease control
Last updated May 26, 2026 08:31 UTC
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Virtual coach aims to kick smoking and boost activity
Disease control CompletedThis study tested a virtual coach designed to help adults quit smoking and become more physically active. About 100 participants used the coach for around 16 weeks. Researchers measured how well people liked and used the program, and whether it helped them change their habits.
Matched conditions: SMOKING
Phase: NA • Sponsor: Leiden University Medical Center • Aim: Disease control
Last updated May 26, 2026 08:30 UTC
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Phone app helps PTSD smokers kick the habit for good
Disease control CompletedThis study tested whether a smartphone app could help people with PTSD quit smoking and avoid relapsing. Participants received counseling, stop-smoking medications, and a mobile app that rewarded them for not smoking. The study enrolled 15 adults who smoked at least 10 cigarettes…
Matched conditions: SMOKING
Phase: NA • Sponsor: Duke University • Aim: Disease control
Last updated May 22, 2026 13:50 UTC
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New therapy helps smokers with HIV kick the habit
Disease control CompletedThis study tested a new type of counseling called BAPS to help smokers with HIV quit smoking. 651 participants were split into two groups: one received standard smoking cessation counseling, and the other received BAPS therapy. The goal was to see which approach led to more peopl…
Matched conditions: SMOKING
Phase: NA • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated May 19, 2026 12:01 UTC
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Phone therapy helps smokers quit: new study shows promise
Disease control CompletedThis study tested a telephone-based guided imagery program to help adults quit smoking. Over 1,200 daily smokers from Arizona, New York, and West Virginia took part. Participants received coaching calls and were checked at 3 and 6 months to see if they had quit, using breath test…
Matched conditions: SMOKING
Phase: NA • Sponsor: University of Arizona • Aim: Disease control
Last updated May 19, 2026 12:00 UTC
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Tailored smoking treatment shows promise for Low-Income patients
Disease control CompletedThis study tested a personalized approach to help people quit smoking by matching medication to their nicotine metabolism. It involved 606 adults on Medicaid or Medicare who smoked daily. The goal was to see if tailoring treatment leads to higher quit rates.
Matched conditions: SMOKING
Phase: PHASE3 • Sponsor: Vanderbilt-Ingram Cancer Center • Aim: Disease control
Last updated May 19, 2026 11:59 UTC
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New combo therapy helps veterans quit smoking and tackle PTSD
Disease control CompletedThis study tested a new treatment for veterans who smoke and have PTSD. It combined a proven PTSD therapy with extra support to help them quit smoking, including counseling and rewards for staying smoke-free. 120 veterans took part to see if this approach helped them stop smoking…
Matched conditions: SMOKING
Phase: PHASE4 • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated May 18, 2026 12:12 UTC
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Berry power: black raspberry lozenges may shield Smokers' DNA
Disease control CompletedThis study looked at whether black raspberry lozenges could lower harmful DNA changes in mouth cells caused by smoking. 69 adult smokers took the lozenges for several weeks. The goal was to see if the berries could reduce damage linked to cancer risk. Results may help find a simp…
Matched conditions: SMOKING
Phase: NA • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated May 18, 2026 12:03 UTC
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Laser therapy Deep-Cleans Smokers' gums better than standard care
Symptom relief CompletedThis study tested whether adding a diode laser to standard deep-cleaning treatment helps smokers with severe gum disease. Thirty-three smokers were randomly assigned to get either standard cleaning alone or cleaning plus laser. After three months, the laser group had significantl…
Matched conditions: SMOKING
Phase: NA • Sponsor: Selcuk University • Aim: Symptom relief
Last updated May 26, 2026 08:45 UTC
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Free samples of Stop-Smoking drugs tested in remote trial
Symptom relief CompletedThis study tested whether mailing free samples of varenicline or nicotine patches/lozenges helps smokers quit. 652 daily smokers were randomly assigned to receive a free sample of varenicline, nicotine products, or no sample. Participants completed surveys and daily diaries for 6…
Matched conditions: SMOKING
Phase: PHASE1, PHASE2 • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated May 26, 2026 08:45 UTC
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New program aims to help lung cancer patients kick the habit
Symptom relief CompletedThis study tested a program to help lung cancer patients stop smoking and avoid starting again. It included 21 participants and used phone calls and online videos for support. The main goal was to see if the program was easy to use and liked by patients.
Matched conditions: SMOKING
Phase: NA • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Symptom relief
Last updated May 26, 2026 08:41 UTC
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New program tackles smoking and mental health in HIV patients
Symptom relief CompletedThis study tested a 9-session program that uses cognitive-behavioral techniques to help people living with HIV quit smoking by reducing anxiety and depression. 131 daily smokers who were motivated to quit took part. The goal was to see if the program led to higher quit rates comp…
Matched conditions: SMOKING
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated May 26, 2026 08:28 UTC
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Cash for clean breath: new program helps homeless vets quit smoking
Symptom relief CompletedThis study tested a program to help homeless veterans quit smoking. Participants received nicotine patches, gum or lozenges, plus counseling. They also earned money by recording videos of their breath carbon monoxide levels to prove they weren't smoking. The goal was to see if th…
Matched conditions: SMOKING
Phase: NA • Sponsor: Duke University • Aim: Symptom relief
Last updated May 22, 2026 14:04 UTC
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Hospital program helps teens kick vaping habit
Symptom relief CompletedThis study tested a program to help teens and young adults (ages 14-21) who vape or smoke to quit. The program was offered to 144 participants while they were in the hospital. Researchers checked if participants had stopped using tobacco or e-cigarettes 30 days after the program,…
Matched conditions: SMOKING
Phase: NA • Sponsor: Children's Mercy Hospital Kansas City • Aim: Symptom relief
Last updated May 22, 2026 13:54 UTC
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Can your Phone's camera help you quit smoking?
Symptom relief CompletedThis study tested a smartphone app that uses augmented reality (AR) to help reduce cravings to smoke. 14 adults who had recently quit smoking tried the app and rated how easy it was to use and how satisfied they were. The goal was to see if the app is a helpful and user-friendly …
Matched conditions: SMOKING
Phase: NA • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Symptom relief
Last updated May 20, 2026 11:56 UTC
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Hospital program helps caregivers kick the habit during child's stay
Symptom relief CompletedThis study tested whether caregivers of hospitalized children would use a smoking cessation program. Participants received a 20-minute counseling session and nicotine patches and lozenges for two weeks. The goal was to see if the program was helpful and could be offered hospital-…
Matched conditions: SMOKING
Phase: PHASE4 • Sponsor: University of Wisconsin, Madison • Aim: Symptom relief
Last updated May 18, 2026 12:13 UTC
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Heated tobacco vs cigarettes: new study measures body toxins and inflammation
Knowledge-focused CompletedThis study looked at nearly 1,000 adults aged 30-60 to see if using a tobacco heating system for at least 2 years leads to lower levels of harmful chemicals, oxidative stress, and inflammation compared to smoking cigarettes. Participants were grouped by their smoking habits and m…
Matched conditions: SMOKING
Sponsor: Philip Morris Products S.A. • Aim: Knowledge-focused
Last updated May 26, 2026 08:43 UTC
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Saliva test reveals smoking and gum disease wreck your DNA
Knowledge-focused CompletedThis study looked at whether smoking and severe gum disease (Stage III periodontitis) cause damage to DNA and RNA, the building blocks of your cells. Researchers measured two markers of cell damage in the saliva of 88 adults, including smokers and non-smokers with and without gum…
Matched conditions: SMOKING
Sponsor: Zehra Hasgül • Aim: Knowledge-focused
Last updated May 26, 2026 08:39 UTC
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Nicotine pouches put to the test: will they hook smokers?
Knowledge-focused CompletedThis study tested six different nicotine oral products (like pouches or lozenges) in 40 healthy adult smokers to see how appealing and addictive they might be. Researchers measured how much people liked them and how much nicotine entered the blood. The goal was to understand the …
Matched conditions: SMOKING
Phase: NA • Sponsor: RAI Services Company • Aim: Knowledge-focused
Last updated May 26, 2026 08:34 UTC
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E-Hookah vaping harms blood vessels – nicotine is the culprit
Knowledge-focused CompletedThis study measured how e-hookah vaping affects the cells lining blood vessels in 33 young adults aged 21–39. Researchers compared the effects of nicotine-containing and nicotine-free vapor to see if nicotine was responsible for blood vessel damage. The goal was to understand the…
Matched conditions: SMOKING
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated May 26, 2026 08:30 UTC
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Can a 4-Minute workout help Smokers' inflammation?
Knowledge-focused CompletedThis study looked at how a short, intense workout called Tabata affects certain markers of inflammation in smokers compared to non-smokers. 40 adults aged 18-40 who were not regular exercisers took part. Researchers measured levels of nitric oxide and maresin in the blood to see …
Matched conditions: SMOKING
Phase: NA • Sponsor: Ataturk University • Aim: Knowledge-focused
Last updated May 26, 2026 08:28 UTC
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Stress and smoking: new study explores racial differences
Knowledge-focused CompletedThis study looked at how stress affects smoking in African American and white men. Researchers measured stress responses using a psychological test and tracked daily cortisol patterns. The goal was to understand racial differences in stress and smoking behaviors. 95 male smokers …
Matched conditions: SMOKING
Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC
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Can 'nudges' help smokers with mental illness kick the habit?
Knowledge-focused CompletedThis pilot study tested a program called 'Nudges to Quit' to help people with serious mental illness stop smoking. The program used gentle reminders for patients, their case workers, and pharmacists to offer smoking-cessation help. The goal was to see if this approach was practic…
Matched conditions: SMOKING
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated May 22, 2026 13:55 UTC
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Fruity cigars may hook young smokers even more
Knowledge-focused CompletedThis study looked at whether little cigars and cigarillos (LCCs) are addictive, especially when flavored like fruit, and if men and women respond differently. Researchers studied 65 young adults who smoke both LCCs and cigarettes. They measured how much people would smoke as pric…
Matched conditions: SMOKING
Phase: NA • Sponsor: UConn Health • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC
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12-year dental study reveals key factor for implant success
Knowledge-focused CompletedThis study examined 142 patients who had sinus lift surgery to place dental implants. Researchers measured how much bone was present before surgery and tracked bone loss around the implants for up to 12 years. They also considered smoking and diabetes to get a clearer picture of …
Matched conditions: SMOKING
Sponsor: Saint-Joseph University • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC