SMOKING

This study is testing whether a new smartphone app that uses augmented reality can help people quit smoking. The app is designed to be used alongside standard telephone counseling from a quitline. Researchers want to see if people who use the app in addition to counseling are mor…

This study is testing how well a non-invasive brain stimulation treatment can be offered in a clinic to help daily smokers quit. The treatment, called rTMS, uses magnetic pulses to target brain areas linked to craving and decision-making. Researchers want to learn if patients and…

This study is testing a 24-week community program designed to improve heart health and reduce stress in Black men who have risk factors like high blood pressure or prediabetes. Participants are randomly assigned to either start the program right away or join a waitlist, and they …

This study is testing a new program where community pharmacists help people in rural Appalachia quit smoking. It will compare different combinations of support, like text messages, phone coaching, and nicotine replacement therapy (patches and lozenges), to see what works best. Th…

This study aims to help people living with HIV quit smoking by offering them different nicotine replacement options like e-cigarettes, nicotine pouches, or patches. Researchers want to see which approach works best to help participants stop smoking tobacco cigarettes for at least…

This small pilot study is testing whether giving cancer patients an indoor air quality monitor helps them keep their homes smoke-free. Researchers want to see if using the monitor for two weeks is practical and if patients attend related workshops. The goal is to improve air qual…

This study aims to see if a person's unique brain activity can predict which type of non-invasive brain stimulation helps them smoke less. Researchers will use brain scans and a technique called rTMS on 100 adult smokers. The goal is to match the right brain stimulation treatment…

This study is testing whether a motivational AI chatbot on your phone can help people quit smoking. Researchers will enroll 440 adult smokers to use the digital coach, which provides encouragement, education, and helps create a personalized quit plan. The main goal is to see if p…

This study is testing whether an investigational medication called brenipatide can help adults who have recently quit smoking avoid relapsing back to cigarettes. About 222 participants will receive either brenipatide or a placebo (inactive substance) via self-injection for 24 wee…

This study tests a new way to help people in rural areas who smoke but aren't ready to quit. It trains local paramedics to connect smokers with a free mobile phone game called 'Take a Break,' which guides them through short periods of not smoking. The goal is to build skills and …

This study is testing whether the flavor of an e-cigarette makes it easier for long-term smokers to switch from regular cigarettes. Researchers will give 210 persistent smokers either fruit, tobacco, or menthol flavored e-cigarettes to use for six weeks instead of smoking. The go…

This study aims to find out if switching to e-cigarettes or oral nicotine pouches helps adults who smoke reduce their cigarette use. Researchers will give 256 participants one of these products for 4 weeks, testing different flavors and nicotine strengths. The main goal is to see…

This study is testing a personalized plan to help cancer patients quit smoking. It uses a patient's own genetic and health information to recommend the best quit-smoking medications. The goal is to see if this tailored approach helps more patients successfully quit and improves t…

This study aims to measure whether switching from regular cigarettes to heated tobacco devices reduces exposure to harmful chemicals found in smoke. 108 adult smokers will either switch to different heated tobacco device versions or continue smoking regular cigarettes for compari…

This study is testing whether a personalized support program helps smokers who have cancer quit. About 1,450 participants in Hong Kong will either get brief advice to quit immediately or get to choose their own quit date and receive encouraging text messages for 6 months. The goa…

This study is testing a new self-help booklet designed to increase motivation to quit smoking in people recently diagnosed with specific cancers. Researchers want to see if the booklet is practical for patients to use and if they find it helpful. The study will also track if part…

This pilot study is testing an online therapy program designed to help people quit smoking while also managing feelings of stress, anxiety, or depression. The program teaches skills based on a therapy called Dialectical Behaviour Therapy. Researchers will recruit 60 adult smokers…

This study is testing a 24-week lifestyle program called Inspire HER, designed specifically for Black women at risk for heart disease. The program provides health education, physical activity guidance, and social support resources. Researchers will compare the program's effective…

This study tests whether personalized treatment recommendations based on a person's genetic and health information can help smokers quit more effectively than standard care. The research involves 850 adult smokers and their doctors across primary care clinics. It compares the new…

This study is testing whether taking kava, a natural herb, can help people quit smoking. Researchers want to see if kava reduces the stress and sleep problems that often make quitting difficult. The trial involves 76 adult smokers who want to quit and will track their smoking hab…

This study is testing whether switching cancer patients who smoke to e-cigarettes is a helpful alternative when they refuse all standard quit-smoking treatments. Researchers will compare e-cigarette use to standard care in 208 patients to see which approach helps more people stop…

This study aims to understand how well a lung cancer screening program works for people at high risk in Taiwan. It will enroll over 6,600 participants, including former heavy smokers, people with a family history of lung cancer, and those exposed to certain environmental risks li…

This study aims to see if specific chest exercises can help improve breathing and fitness in young adults who smoke. Researchers will compare two different exercise programs—one using specialized PNF techniques and another using standard chest mobility exercises—against a control…

This study is testing if switching from regular cigarettes to a tobacco heating system (THS) can help adults with COPD feel better. It will compare people who switch to THS with those who keep smoking cigarettes, looking for changes in coughing, shortness of breath, and lung func…

This study aims to collect blood, urine, and airway samples from both healthy people and people with lung diseases like COPD and pulmonary fibrosis. Researchers will compare the samples to understand what causes these diseases and how they develop. The goal is to gather basic inf…

This study aims to understand how different oral nicotine products affect smokers compared to their usual cigarettes or nicotine gum. It will measure cravings, feelings, and nicotine levels in the blood. About 40 adult smokers will stay at a clinic for several days to try differe…

This study aims to understand the link between gum disease, smoking, and specific inflammation markers in saliva. Researchers will compare saliva samples from 116 people with and without gum disease, who are either smokers or non-smokers. The goal is to see if these markers could…