SMOKING

This study tests whether adding a special talk therapy (CBASP) to standard smoking cessation help can improve quit rates in people with depression. About 91 smokers with current major depression or dysthymia will be randomly assigned to either CBASP plus standard treatment or hea…

This study tests a program called ESCAPE, which combines smoking cessation support with education about lung cancer screening. It is for adults aged 55-77 who smoke heavily and have not had a lung scan. The goal is to see if the program helps more people quit smoking and get scre…

This study looks at whether switching completely from regular cigarettes to e-cigarettes can reduce harm for cancer patients who smoke but refuse standard quitting treatments. About 208 adults with cancer who smoke will be offered e-cigarettes and followed for 6 months to see if …

This study tests whether atorvastatin, a widely used cholesterol medication, can reduce lung inflammation and prevent flare-ups in smokers with COPD. About 460 participants will receive either atorvastatin or a placebo for several months. The goal is to see if the drug can help c…

This study tests a program that trains pharmacists to help people living with HIV quit smoking. The program gives pharmacists tools and support to offer smoking cessation counseling and medications. Researchers will see if this approach helps more patients stop smoking and improv…

This study tests whether a daily kava drink can help active smokers (who don't plan to quit) smoke less and lower their risk of lung cancer. Twenty adults who smoke at least 5 cigarettes a day will take kava for 4 months. Researchers will check how well participants stick with th…

This study tests a proactive outreach program to help BIPOC adults who smoke quit tobacco. Researchers will use electronic health records to identify smokers and offer culturally tailored support, including counseling and medication. The goal is to reduce smoking rates and relate…

This study tests whether an online training program helps people who recently quit smoking stay smoke-free and support others in their social network to quit. About 940 adults who have been smoke-free for 2 to 8 weeks will take part. Participants will complete surveys and provide…

This study is testing a smartphone app designed to help people reduce or quit smoking. Participants use the app along with nicotine patches to see if the combination is helpful. The goal is to learn how easy the app is to use and whether it can support quitting. The study involve…

This study aims to develop a digital outreach strategy to inform women about lung cancer screening. Researchers will contact women aged 50–80 who recently had a normal mammogram and have a significant smoking history. The goal is to see if email and a web-based tool can increase …

This study looks at whether sending simple reminders (nudges) to doctors, patients, or both can increase the number of people with HIV who get help to quit smoking. About 500 patients and their doctors will take part. The goal is to see which approach works best to connect patien…

This study looks at how smokers with different reading skills respond to health messages about smoking. About 500 smokers listened to and read four types of messages that varied in emotional tone and whether they focused on the benefits of quitting or the risks of continuing. The…

This study tests if wearable devices like smartwatches can detect changes in heart rate, breathing, and hand movements that happen before, during, and after smoking. About 30 adults who smoke will wear a smartwatch for 3 days at home and then visit a lab for monitoring. The goal …

This study follows about 3,000 adults in Port-au-Prince, Haiti, for up to 7 years to learn how common heart disease risk factors like high blood pressure, diabetes, and smoking are, and how they lead to heart attacks, strokes, and other problems. Participants give blood, stool, a…

This study tests whether giving doctors and patients a personalized risk report (based on clinical or genetic information) increases the number of people who get screened for lung cancer and receive help to quit smoking. About 915 patients and their primary care doctors are takin…

This study looks at how different tobacco products—like cigarettes, e-cigarettes, and smokeless tobacco—affect the way skin wounds heal. Researchers will measure skin temperature, blood flow, and signs of inflammation in 60 adults, including a group of non-smokers for comparison.…

This study follows 100 head and neck or lung cancer patients who smoke or used to smoke. Researchers want to see what helps them stay away from cigarettes after they finish radiation or chemoradiation. Patients are checked at 1, 6, and 12 months after treatment ends. The goal is …

This study looks at how to help VA medical centers offer virtual programs that prevent heart disease, diabetes, and depression in women Veterans. It involves 20 VA sites across 4 regions, testing two different support strategies. The goal is to see which approach gets more women …

This study looks at how Salvation Army staff can help people who smoke learn about and use free services to quit. About 233 adults who use Salvation Army services will take part. Researchers will track how many people are referred to the Wisconsin Tobacco Quit Line and how many a…