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Saliva test reveals smoking and gum disease wreck your DNA

NCT ID NCT07279896

First seen Jan 07, 2026 · Last updated May 23, 2026 · Updated 25 times

Summary

This study looked at whether smoking and severe gum disease (Stage III periodontitis) cause damage to DNA and RNA, the building blocks of your cells. Researchers measured two markers of cell damage in the saliva of 88 adults, including smokers and non-smokers with and without gum disease. They found that people with gum disease had more DNA and RNA damage, and smokers with gum disease had the highest levels. The results suggest that a simple saliva test could help detect gum disease and show how smoking adds to cell damage.

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Contacts and locations

Locations

  • Ankara University Faculty of Dentistry, Department of Periodontology

    Ankara, Yenimahalle, 06560, Turkey (Türkiye)

Conditions

Explore the condition pages connected to this study.