PERIODONTAL DISEASES

This study looked at whether smokers who switch to e-cigarettes or heat-not-burn products see improvements in their gum health and tooth appearance. About 460 healthy adult smokers were followed for 18 months and compared to those who kept smoking and those who never smoked. The …

This study tested a modified minimally invasive surgical technique (M-MIST) alone or combined with enamel matrix derivative and bone graft to treat isolated gum disease bone defects. 45 adults with deep gum pockets and bone loss participated. The goal was to see if adding these m…

This study tested a new method to repair bone gaps around dental implants placed right after tooth removal. 63 adults with damaged front teeth received implants alone, with a tooth graft, or with a tooth graft plus a tooth plate. The tooth plate group showed better bone healing a…

This study tested whether a special bone graft material containing zinc, combined with a patient's own blood concentrate (platelet-rich fibrin), can help repair bone damage caused by gum disease. Thirty adults with gum disease bone defects received the treatment, and researchers …

This study tested whether a hyaluronic acid gel or a chlorhexidine mouthwash works better as an at-home treatment after deep cleaning for gum disease. Forty adults with periodontitis used one of the two products for 15 days and were followed for 6 months. The goal was to see whic…

This study looked at whether adding a 980nm diode laser to standard deep cleaning helps treat gum disease better than cleaning alone. It included 40 people with gum disease, some of whom had a recent heart attack. Researchers measured gum pocket depth, bleeding, and blood markers…

This study tested whether a probiotic called TCI188 (Pediococcus acidilactici) can improve oral health in 55 adults with severe gum disease (periodontitis). Researchers measured changes in gum pocket depth, bleeding, plaque, and gum attachment levels. The goal was to see if the p…

This study looked at whether using a specially sized (calibrated) interdental brush is better than a regular one for keeping gums healthy in young adults aged 18 to 30. Over three months, 51 participants used either a calibrated or non-calibrated brush daily. The main goal was to…

This study tested whether a chewing gum containing dietary nitrate (a natural compound found in leafy greens and beets) could improve gum health and heart health in adults with mild to moderate gum irritation or bleeding. Thirty participants were randomly assigned to use either t…

This study tested a gum surgery technique (EPPT) alone or with enamel matrix proteins and a bone graft to repair bone damage from gum disease. 58 adults with moderate to severe gum disease and isolated bone defects participated. The goal was to see if adding the proteins and graf…

This study tested a gum surgery that combines a connective tissue graft with enamel matrix derivative to treat deep gum disease pockets. Seventeen adults with advanced periodontitis received the treatment, and researchers measured bone fill, gum attachment, and tissue stability o…

This study tested whether adding antimicrobial photodynamic therapy (aPDT) — a treatment that uses light to kill bacteria — to standard deep cleaning improves outcomes for people with gum disease. Twenty adults with deep gum pockets and bleeding participated. Researchers measured…

This study tested whether lozenges made from propolis (a bee product) could reduce gum inflammation and plaque in 100 adults aged 19–24 with moderate gingivitis. Participants used the lozenges for one week, while a control group only received oral hygiene instructions. Researcher…

This study looked at three substances in saliva (HIF-2α, MMP-9, and TRAP-5b) to see if they can tell the difference between healthy gums, gingivitis (mild gum inflammation), and periodontitis (serious gum disease). Researchers tested 60 non-smoking, healthy adults who had not tak…

This study tested a new way to treat gum disease that may cause less tooth sensitivity. 40 adults with advanced gum disease had half their mouth treated with a standard tool and the other half with an ultrasonic tool that uses hydroxyapatite (a natural tooth mineral). The goal wa…

This study tested whether adding a substance made from a patient's own blood (L-PRF) to standard gum surgery improves healing and reduces pain. Twenty-one adults with gum disease had both types of surgery on different sides of their mouth. Researchers measured pocket depth and pa…

This study examined whether knowing dental health terms is linked to gum health in 108 Turkish adults. Participants took a reading test about dental words and had a gum exam. The goal was to see if people with lower health literacy have worse gum disease, highlighting the need fo…

This study looked at 61 adults with peripheral artery disease to see if gum health affects levels of TMAO, a chemical linked to heart problems. Researchers measured TMAO in blood and saliva and compared people with healthy gums, gum disease, or no teeth. The goal was to understan…

This study looked at 36 adults with rheumatoid arthritis to see if the severity of their gum disease was linked to levels of certain antibodies (ACPAs) in their gum fluid. Researchers measured these antibodies before and after non-surgical gum treatment. The goal was to better un…

This study examined the link between smoking and gum health in 484 adults. Participants were divided into smokers and non-smokers, and their gums were checked for signs of disease. The goal was to understand how smoking habits relate to gum problems like periodontitis.

This study examined 318 adults to see if coffee drinking habits are linked to gum health. Participants were grouped by gum condition (healthy, gingivitis, or periodontitis) and asked about their coffee intake. Researchers measured plaque, bleeding, and gum pocket depth to find an…

This study looked at whether three substances found in saliva (Adseverin, 1-Alpha defensin, and sRANKL) can help tell the difference between healthy gums, gingivitis, and more serious gum disease (periodontitis). Researchers collected saliva from 60 non-smoking adults and compare…

This study looked at 56 extracted human teeth to see how three different polishing methods—bristle brush, rubber cup, and air polishing—affect tooth surface roughness after scaling. The goal was to find which method leaves teeth smoothest, which could help prevent plaque buildup.…

This study looked at the link between psoriasis (a chronic skin condition) and gum health. Researchers examined 226 adults—some with psoriasis and some without—to see if psoriasis affects the gums and overall quality of life. Participants had an oral exam and filled out questionn…

This study looked at two proteins, Dkk-1 and sFRP5, in the gum fluid of 99 people with healthy gums, gingivitis, or periodontitis. Researchers measured these proteins before and after a standard deep-cleaning treatment to see if they change with gum inflammation and bone loss. Th…

This study looked at 227 HIV patients on antiretroviral therapy to see if poor oral health (like cavities and gum disease) is linked to metabolic problems and ongoing inflammation. Researchers measured dental health, bone density, and quality of life. The goal was to understand h…

This study looked at 60 people to explore a possible link between gum disease (periodontitis) and Parkinson's disease. Researchers measured certain substances in saliva and blood related to inflammation. They found higher levels of some tryptophan metabolites in people with both …

This study looked at whether eating einkorn, an ancient cereal, could change the types of bacteria in the mouth. Researchers measured harmful bacteria linked to cancer risk in 31 healthy adults before and after adding einkorn to their diet. The goal was to see if a simple dietary…

This study looked at a protein called pentraxin in the gum fluid of people with fixed dentures. The goal was to see if pentraxin levels can help detect early gum disease that isn't visible during a regular checkup. Researchers studied 90 adults who needed fixed dentures and had n…

This study looked at 293 Egyptian adults with multiple sclerosis to see how common gum disease is in this group. Researchers performed a standard dental exam to measure gum health. The goal was to find out if there is a connection between MS and periodontal disease.

This study looked at the types of bacteria in the mouths of 30 people—some with gastritis (stomach inflammation) and some without. Researchers wanted to see if stomach problems are linked to gum health by comparing the oral microbiome. No treatment was given; the goal was simply …

This completed study looked at 100 people with gum disease, some with obesity and some without, to see how non-surgical gum cleaning affects the body's immune system. Researchers compared men and women to find differences in immune response and looked for tiny molecules called mi…

This study looked at 400 dental and medical students to see if their oral health affects their quality of life. Researchers checked for gum disease, cavities, and other dental problems, and asked students how they feel about their oral health. The goal was to understand the link …

This study looked at a protein called IL-36α in the saliva and gum fluid of 80 people with healthy gums, gingivitis, or periodontitis. Researchers wanted to see if levels of this protein differ between these groups and relate to standard measures of gum health. The goal was to be…