PERIODONTAL DISEASES

This study compares three different surgical techniques to repair gum damage caused by periodontitis. Researchers will enroll 60 adults with deep gum pockets and bone loss. The goal is to see which method best reduces pocket depth and improves gum attachment, helping control the …

This study tests whether a collagen matrix can help regrow bone and gum tissue damaged by severe gum disease, compared to a standard bone-graft material. About 80 adults with deep gum pockets will receive one of the two treatments during surgery. The goal is to see which material…

This study tests whether a gel containing lovastatin (a cholesterol drug) placed under the gum can improve standard deep-cleaning treatment for periodontitis. About 44 adults, both smokers and non-smokers, will receive the medicated gel on one tooth and a placebo gel on another t…

This study tests whether a special dental gel, used at home, can improve gum health more than standard care alone in people with moderate to severe gum disease (periodontitis). About 76 adults will use the gel after a deep cleaning and be followed for 6 months. The main goal is t…

This study tests a new way to surgically treat gum disease. Instead of removing the granulation tissue (the body's natural healing tissue) during surgery, the new method preserves it to help the gums heal better. The study will compare this new approach to the standard surgery in…

This study tests whether a telehealth program can help cancer survivors prevent mouth sores, gum disease, and tooth decay, and improve their quality of life. About 100 cancer survivors who finished treatment at least 6 months ago will either get the telehealth program or usual ca…

This study tests whether adding a special gel made from a patient's own blood (injectable platelet-rich fibrin) to a standard bone graft helps repair deep bone defects caused by gum disease. Sixteen adults with advanced periodontitis will receive either the combination treatment …

This study tests if using a sodium bicarbonate (baking soda) fluoride toothpaste every day can help maintain gum health in adults who have already had non-surgical gum treatment. One hundred participants will use either the special toothpaste or a placebo and have their gum healt…

This study aims to see if an online questionnaire can accurately assess a person's risk for gum disease (periodontitis or gingivitis). About 393 adults in Saudi Arabia will fill out the questionnaire and then get a dental exam to compare results. The goal is to create a simple, r…

This study compares two types of stitches (Novosyn Quick and Monosyn Quick) used during gum surgery to see if they heal equally well. About 84 adults having gum surgery will be randomly assigned one of the two stitches. The main goal is to check early healing signs like skin regr…

This study tests whether using a microscope during gum surgery helps the gums heal better than using standard magnifying glasses (dental loupes). About 25 adults with gum disease will have their gum flap surgery done with either a microscope or loupes. The main goal is to see if …

This study looks at two types of gum tissue in people with severe gum disease to see how they affect healing after treatment. Researchers will collect tissue samples during gum surgery and compare smokers to non-smokers. The goal is to understand why some tissues heal better and …

This study looks at whether training medical staff and updating electronic health records can encourage older adults (55+) on Medicaid to visit the dentist more often. About 929 participants from 12 clinics will be split into two groups: one gets enhanced support and education, t…

This study looks at how the severity of pemphigus vulgaris, a chronic autoimmune skin disease, relates to gum health. Researchers will measure mouth sores and blood markers in 20 adults and compare them with standard gum measurements. The goal is to understand if worse disease le…

This study looks at whether certain markers in blood and saliva can help predict how well people with gum disease will heal after non-surgical treatment. Researchers will measure these markers in 180 adults (healthy, with gingivitis, or with advanced periodontitis) before and aft…