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Laser zaps gum bugs to protect hearts after attack

NCT ID NCT04145557

Disease control Sponsor: Pomeranian Medical University Szczecin Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested whether adding a 980nm diode laser to standard deep-cleaning gum treatment improves gum health and reduces body-wide inflammation in people who recently had a heart attack. Forty participants with gum disease (some healthy, some heart attack survivors) received either standard scaling and root planing alone or with laser therapy. Researchers measured pocket depths, bleeding, and blood markers of inflammation before, 2 weeks, and 3 months after treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
980nm diode laser
What this could lead to
If successful, this could show that laser gum therapy helps reduce inflammation linked to heart disease, pointing toward better post-heart-attack care.
What could go wrong
This is a small, completed study with only 40 participants, so results may not apply widely. The laser is an add-on to standard care, not a standalone treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Aug 2019

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

35 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 1\. myocardial infarction treated with primary coronary angioplasty in the last 6 months, 2. age \<65 years 3. Periodontitis diagnosed according to Page criterion - * ≥ 2 tooth surfaces on interprimimal spaces with a loss of CAL≥4mm (not for the same tooth) * ≥2 tooth surface in the interpharmal space with PD≥4mm * positive bleeding on probing test (BOP) 4. signed informed consent Exclusion Criteria: 1. Acute inflammation of the airways or urinary tract 2. Neoplasmas 3. Rheumatic diseases 4. Autoimmune diseases 5. Chronic liver disease 6. Chronic kidney failure 4. and 5. stage 7. History of a stroke or TIA 8. Lack of consent for participation in the study 9. Antibiotic therapy in the last 12 months 10. Periodontal treatment in the last 6 months 11. Participation in other studies

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Conditions

The condition(s) this trial relates to.

myocardial infarction periodontal disorder periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Myocardial infarction Periodontal diseases

Contacts and locations

Locations

  • Departament of Periodontology

    Szczecin, 70-204, Poland

More trials for these conditions

Other studies related to the condition(s) this trial covers.