NON-ALCOHOLIC FATTY LIVER DISEASE

This study looked at whether alternating between a day of fasting and a day of normal eating, combined with exercise, can reduce liver fat in people with non-alcoholic fatty liver disease (NAFLD). The trial included 80 obese adults who were not very active. Researchers measured c…

This study tested whether drinking Jing-Si Herbal Tea for 24 weeks can improve health markers in people with non-alcoholic fatty liver disease (NAFLD). Researchers measured changes in blood sugar, liver enzymes, cholesterol, and liver fat activity. The study involved 108 adults a…

This study looked at whether motivational interviewing, a type of counseling, can help people with non-alcoholic fatty liver disease (NAFLD) lose weight. Over 200 adults with NAFLD and a BMI of 25 or higher took part. Researchers measured weight, liver enzymes, and body fat chang…

This study tested whether ornithine aspartic acid granules work as well as or better than silymarin capsules for non-alcoholic fatty liver disease (NAFLD). 237 adults with NAFLD and high liver enzymes took one of the two treatments for a period. The main goal was to see if liver …

This study tested a single dose of an experimental drug called GSK4532990 in 61 adults with non-alcoholic fatty liver disease (NASH). The goal was to see how the drug moves through the body, how it affects the liver, and whether it is safe. Participants were followed for about 24…

This study tested whether three types of probiotics (Lactobacillus and Pediococcus strains) can improve liver health in people with non-alcoholic fatty liver disease. 89 adults took either a probiotic or a placebo daily for 8 weeks, along with a standard liver medication. Researc…

This study tested whether giving people with non-alcoholic fatty liver disease a device to measure their liver fat at home helps them lose more liver fat through diet and exercise. Ten adults from two Hong Kong hospitals took part. The idea was that seeing their own liver fat num…

This study tested a drug called tesamorelin in 51 obese adults with nonalcoholic fatty liver disease (NAFLD). The drug aims to boost growth hormone levels, which may reduce liver fat and inflammation. Researchers measured liver fat with special scans and biopsies to see if the tr…

This study tested a new medicine called efinopegdutide in 381 adults with non-alcoholic steatohepatitis (NASH), a serious liver condition. The main goal was to see if the drug could stop signs of NASH without making liver scarring worse. Researchers also checked for side effects …

This study looked at whether changing the amount of methyl donor nutrients (like folate and choline) in the diet could help people with non-alcoholic fatty liver disease (NAFLD). 51 adults with low levels of these nutrients were enrolled. Researchers measured liver fat, body fat,…

This study tested whether a probiotic called L. lactis CKDB001 can improve liver health in people with nonalcoholic fatty liver disease (NAFLD). About 95 adults with mildly elevated liver enzymes took the probiotic or a placebo for 12 weeks. The main goal was to see if the probio…

This study looked at whether a special ultrasound technique can accurately measure liver fat in children aged 6-17 with suspected non-alcoholic fatty liver disease. About 90 children had both an ultrasound and an MRI scan. The goal was to see if the ultrasound results matched the…

This early-stage study tested a new medicine called BI 3006337 in 64 adults who are overweight or have obesity and also have fatty liver disease. The main goal was to see if different doses of the weekly injection are safe and tolerable. Participants received either the drug or a…

This study checked if a special MRI scan called LiverMultiScan gives the same results when repeated on the same machine or on different machines. 61 adults with various liver diseases were scanned multiple times. The goal was to see if the scan reliably measures liver fat, iron, …

This study tested a new ultrasound feature that measures liver fat by comparing it to the standard MRI method. 60 adults with or at risk for fatty liver disease had both scans. The goal was to see if the simpler, cheaper ultrasound could give reliable results, potentially making …

This study looked at how different amounts of insulin affect blood sugar in people with overweight, prediabetes, and fatty liver disease. Researchers used a special clamp technique to carefully control insulin levels and measure changes. The goal was to better understand the role…

This study looked at how bacteria in the gut might be involved in non-alcoholic fatty liver disease (NAFLD). Researchers measured the distance between gut microbes and intestinal cells in 38 adults aged 35-65. The goal was to understand if bacteria getting too close to the gut li…

This study looked at whether fatty liver disease can be an early warning sign for heart problems, separate from known risks like high cholesterol. Researchers measured blood markers of liver and blood vessel health in 63 adults aged 50-69 who did not have diabetes. The goal was t…

This study looked at special immune proteins called semaphorins in people with fatty liver disease and NASH. Researchers wanted to see if these proteins are linked to liver damage and inflammation. The study involved 148 obese adults who had liver biopsies and blood tests. The go…

This study examined medical records of 263 adults with biopsy-confirmed NASH to see how factors like age, other health problems, and medications relate to the severity of liver scarring. Researchers focused on metabolic syndrome components as potential risk factors. No treatments…

This early-stage study looked at how lowering high insulin levels with a drug called diazoxide affects the liver in people with or at risk for non-alcoholic fatty liver disease (NAFLD). 24 adults with overweight or obesity took either a low or high dose of diazoxide or a placebo …

This study looked at 67 adults with type 2 diabetes and fatty liver disease who were starting a type of diabetes medication called SGLT2 inhibitors. Researchers used ultrasound and blood tests to measure changes in liver stiffness, fat, and injury markers before and after 6 month…

This study tested a new ultrasound feature that aims to measure liver fat in children, comparing it to the standard MRI method. Thirty children aged 5 to 21 with or at risk for fatty liver disease took part. The goal was to see if the quicker, cheaper ultrasound could give result…

This study looked at 1,000 adults aged 40-80 with type 2 diabetes or obesity to find the best way to screen for advanced liver scarring (fibrosis) caused by fatty liver disease. Researchers compared different non-invasive blood tests and elastography (a special ultrasound) to see…

This study looked at the financial impact of non-alcoholic fatty liver disease (NAFLD) on 73 adults in Flanders, Belgium. Researchers used questionnaires to measure healthcare costs and patient expenses. The goal was to understand the economic burden of the disease, not to test a…

This study looked at how consistent FibroScan, a non-invasive device that measures liver stiffness and fat, is when used by different people on different days. 108 adults with fatty liver or alcohol-related liver disease had multiple scans and blood tests over two visits. The goa…