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Walk and eat your way to a sharper mind? new study tests lifestyle fix for fatty liver

NCT ID NCT07294963

Disease control Sponsor: Khyber Medical University Peshawar Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 19, 2026 · Updated 2 times

Summary

This study tests whether a Mediterranean diet and regular walking can improve memory and thinking in adults with non-alcoholic fatty liver disease (NAFLD). 45 participants aged 18-42 will be split into three groups: general health advice, a structured Mediterranean diet, or the diet plus a walking program. Over six months, researchers will measure changes in cognitive test scores, liver stiffness, and blood markers of inflammation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Structured Mediterranean diet and walking program
What this could lead to
If it works, this could point toward a simple, drug-free way to protect brain function and reduce liver damage in people with fatty liver disease.
What could go wrong
This is a small, early-stage trial with only 45 people, so results may not apply to everyone. Lifestyle changes can be hard to stick with, and the study may not show clear benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

45 people

The number who actually took part.

Started

Oct 2025

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 42 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 to 42 years. * Diagnosed with fatty liver (NAFLD) via imaging (e.g., ultrasound). * Liver fibrosis assessed and staged via FibroScan and the FIB-4 index. * Literate (to consent and complete cognitive assessments/questionnaires). Exclusion Criteria: * History of alcohol intake \>20g/day. * Chronic viral hepatitis B or C. * Major neuropsychiatric illnesses. * Pregnancy or breastfeeding. * Chronic illnesses including Diabetes Mellitus and thyroid dysfunction.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver cognitive disorder Cognitive Dysfunction metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neurocognitive disorders Non-alcoholic fatty liver disease

Contacts and locations

Locations

  • Khyber Teaching Hospital

    Peshawar, KPK, 25100, Pakistan

  • Northwest General Hospital

    Peshawar, KPK, 25100, Pakistan

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