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Scientists Fine-Tune ultrasound to spot fatty liver without needles

NCT ID NCT07616843

Knowledge-focused Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study tested different ways to use an ultrasound machine to measure liver fat in 35 healthy adults. The goal was to find the most reliable technique for non-invasively diagnosing fatty liver disease, a common condition linked to obesity and diabetes. By standardizing the measurement protocol, researchers hope to improve accuracy and reduce the need for liver biopsies.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a more reliable, non-invasive ultrasound method for diagnosing fatty liver disease without needing a biopsy.
What could go wrong
This is a small, early-stage study in healthy volunteers, not patients. The findings may not translate directly to clinical practice or improve patient outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

35 people

The number who actually took part.

Started

Jan 2022

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Healthy adult volunteers

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Informed consent * Healthy adult volunteers (\> 18 years) * Ability to suspend respiration for image acquisition Exclusion Criteria: * Pregnancy * age \< 18 years * Presence of ascites, acute viral hepatitis, transaminase flares, congestive heart failure, infiltrative diseases. * No major medical conditions and in particular no known hepatic diseases * Any other condition that, upon clinical judgment of the investigator, will make unacceptable the study participation for that individual subject * Consent withdrawal

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Conditions

The condition(s) this trial relates to.

fatty liver disease metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Liver steatosis

Contacts and locations

Locations

  • Fondazione IRCCS Policlinico San Matteo, SSD Malattie Infettive 3 - Ecografia

    Pavia, Pavia, 27100, Italy

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