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Talking your way to a healthier liver: study tests motivational coaching for fatty liver

NCT ID NCT06348628

Disease control Sponsor: Madunil Anuk Niriella Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether motivational interviewing, a type of counseling that boosts a person's own desire to change, can help people with non-alcoholic fatty liver disease (NAFLD) lose weight. Over 200 adults with NAFLD and a BMI of 25 or higher took part. Some received four motivational counseling sessions within six months, while others got standard advice. Researchers measured weight, waist size, and liver-related blood tests after one year to see if the counseling made a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Motivational interviewing (behavioral counseling)
What this could lead to
If effective, this approach could provide a simple, drug-free way to help people with fatty liver disease lose weight and improve liver health.
What could go wrong
This is a completed trial, but results are not yet published. Weight loss through counseling can be modest, and long-term benefits for liver disease are uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

231 people

The number who actually took part.

Started

May 2022

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 18 years to 60 years * Body Mass Index (BMI) is 25 kg/m\^2 or more * Newly diagnosed with NAFLD based on clinical history, ultrasound scan and laboratory values Exclusion Criteria: * Any medical condition that will significantly alter the weight eg: hypothyroidism, hyperthyroidism, Cushing disease * Having moderate/severe depressive disorders or psychotic symptoms and or substance use disorders that would reduce their capacity to give consent and engage in Motivational interview * Who are on drugs which will affect weight or mood/affect (eg: corticosteroids) * Pregnancy or expecting to be conceive within the study period * Having any health conditions that would impede engagement in physical activities * Having any health conditions that would compromise the ability to follow the recommended dietary behaviors * Concurrent involvement in another weight loss programme

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Conditions

The condition(s) this trial relates to.

metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Non-alcoholic fatty liver disease

Contacts and locations

Locations

  • Faculty of Medicine, University of Kelaniya

    Ragama, Western Province, 11010, Sri Lanka

More trials for these conditions

Other studies related to the condition(s) this trial covers.