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New weekly shot aims to tackle fatty liver and obesity

NCT ID NCT05970640

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This early-stage trial tested an experimental drug called BI 3006337 in 64 adults who are overweight or obese and have fatty liver disease. Participants received weekly injections of either the drug or a placebo for about 4 months. The main goal was to check safety and tolerability, not yet to see if the drug works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AMR Knoxville

    Knoxville, Tennessee, 37920, United States

  • Accel Research Sites-Deland-67606

    DeLand, Florida, 32720, United States

  • American Research Corporation at the Texas Liver Institute

    San Antonio, Texas, 78215, United States

  • Catalina Research Institute, LLC-Montclair-49051

    Montclair, California, 91763, United States

  • Centricity Research-Columbus-68879

    Columbus, Ohio, 43213, United States

  • Endeavor Clinical Trials

    San Antonio, Texas, 78240, United States

  • Floridian Clinical Research-Miami Lakes-68368

    Miami Lakes, Florida, 33016, United States

  • The Liver Institute at Methodist Dallas

    Dallas, Texas, 75203, United States

  • Velocity Clinical Research-Chula Vista

    Chula Vista, California, 91911, United States

  • Velocity Clinical Research-La Mesa-69117

    La Mesa, California, 91942, United States

  • Velocity Clinical Research-West Jordan-69043

    West Jordan, Utah, 84088, United States

  • iResearch Atlanta

    Decatur, Georgia, 30030, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BI 3006337 (an experimental drug given as a weekly injection)

What this could lead to

If it works, this could point toward a treatment for fatty liver disease in people with overweight or obesity.

What could go wrong

This is a very early Phase 1 trial focused on safety, not effectiveness. The drug may cause side effects or fail to show benefit in larger studies.

Conditions

The condition(s) this trial relates to.

fatty liver disease metabolic dysfunction-associated steatotic liver disease Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.