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Dietary tweak shows promise for fatty liver management

NCT ID NCT05291104

Disease control Sponsor: Fu Jen Catholic University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether changing the amount of methyl donor nutrients (like folate and choline) in the diet could help people with non-alcoholic fatty liver disease (NAFLD). The goal was to reduce liver fat and improve liver function. 51 participants completed the study, and researchers measured changes in liver fat, body fat, and blood markers. The approach focuses on managing the disease through nutrition rather than curing it.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

51 people

The number who actually took part.

Started

Apr 2022

Finished

Jul 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * NAFLD/NASH patients * Folate levels in plasma \< 6 ng/mL or choline levels in plasma \< 5 micromol per liter * Folate intake \< estimated average requirement or choline intake \< 50% adequate Intakes * Homocysteine levels in plasma \> 9 micromol per liter Exclusion Criteria: * Asymptomatic carrier of hepatitis B and C * Liver disease except NAFLD * Taking drugs that causes fatty liver * Inflammation about stomach or intestines * Pregnancy * Cancer except liver cancer * Heart disease, vascular disease, or psychosis * Intake alcohol over 100 g or unaccessible intake alcohol

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Conditions

The condition(s) this trial relates to.

metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Non-alcoholic fatty liver disease

Contacts and locations

Locations

  • Taipei Hospital, Ministry of Health and Welfare

    New Taipei City, 242, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.