MYOCARDIAL INFARCTION

This study looked at how different exercise programs affect heart health in people who recently had a heart attack. 188 adults aged 18-75 were assigned to 12 weeks of high-intensity interval training (HIIT), moderate continuous training, or standard physical activity. The goal wa…

This study tested a new way to help people with two or more long-term health problems like HIV, high blood pressure, diabetes, asthma, or depression. Over 1,800 adults aged 40 and older in South Africa took part. Some clinics used a special decision-support tool and home visits f…

This study looked at whether giving iron through a vein (IV) works better than iron pills to improve the heart's pumping ability after a heart attack. It included 298 adults with low iron levels and heart muscle damage. Researchers measured changes in heart wall motion using ultr…

This study tested a mobile app-based cardiac rehab program for 259 adults who recently had a heart attack, stent, or heart surgery. The goal was to see if using the app improved walking ability, cholesterol, and overall heart health compared to standard in-person rehab. The progr…

This study tested whether the drug henagliflozin, given for 6 months after a heart attack, can reduce the size of heart muscle damage and improve heart function. 248 adults who had a specific type of heart attack (STEMI) and underwent a procedure to open blocked arteries particip…

This study looked at 1,424 veterans with heart problems who had major surgery. It compared giving blood transfusions when hemoglobin drops below 10 (liberal) versus below 7 (restrictive). The goal was to see which approach better prevents serious complications like heart attack, …

This study looked at whether adding a 980nm diode laser to standard deep cleaning helps treat gum disease better than cleaning alone. It included 40 people with gum disease, some of whom had a recent heart attack. Researchers measured gum pocket depth, bleeding, and blood markers…

This study looked at whether sending lifestyle tips and reminders via text message could help people who had a heart attack (acute coronary syndrome) better manage their risk factors and avoid future heart problems. 370 patients took part and received text messages for one year. …

This study tested whether dapagliflozin, a diabetes drug, can help people with type 2 diabetes recover better after a heart attack. Researchers measured inflammation levels and tracked heart-related events like another heart attack or stroke. The goal was to see if the drug impro…

This study tested whether giving atropine, a drug that increases heart rate, can prevent dangerous heart rhythm problems and low blood pressure in people having a specific type of heart attack (inferior ST-elevation) while they undergo a procedure to open blocked arteries. 158 pa…

This study tested a decision support system (DSS) that helps doctors pick the best cholesterol-lowering drugs for patients who just had a heart attack. Over 1,100 patients from different hospitals took part. Hospitals either used the DSS or gave standard care. The goal was to see…

This study looked at 112 adults who had a severe heart attack and multiple blocked arteries. It compared fixing all blockages in a single procedure versus doing them in separate sessions over a month. The goal was to see if the one-time approach reduces hospital stays, costs, and…

This study tested whether giving a low dose of a clot-busting drug (tPA) directly into the heart arteries during emergency angioplasty could improve blood flow and reduce complications in 210 patients having a severe heart attack. The goal was to see if this approach helps clear …

This study looked at whether a team of nurses, doctors, and pharmacists providing close follow-up for two years after a stroke or heart attack is better than standard care. The goal was to see if this approach improves quality of life and reduces hospital readmissions. Over 850 a…

This study tested a newer type of heart stent (Xience Sierra) in 1757 people with heart disease, including many with diabetes or prediabetes. The goal was to see if the stent is safe and works well in both general and high-risk patients. Researchers tracked heart-related events l…

This study looked at whether getting vitamin D levels to a healthy range after a heart attack could lower the chance of having another heart attack, stroke, heart failure, or death. About 634 heart attack patients took part, with half getting standard care and half getting extra …

This study tested a single intravenous infusion of stem cells (PROCHYMAL) in 220 adults who had their first heart attack within the prior week. The goal was to see if the stem cells could safely improve heart function and reduce damage. Participants were randomly assigned to rece…

This study tested a stent retriever, a device used in strokes, to remove blood clots during heart attacks. 81 patients with severe heart attacks were treated either with the new device or standard care. The goal was to see if the stent retriever could reduce damage to small heart…

This study tested a new device that uses sound waves to break up calcium buildup in heart arteries before placing a stent. 145 people with hardened arteries took part. The goal was to see if the device is safe and helps stents work better.

This study looked at 10,000 people who came to the emergency room with chest pain. Researchers tested new blood markers to see if they could diagnose heart attacks faster than current methods. The goal was to help doctors quickly rule out or confirm a heart attack, especially in …

This study looked at whether using different blood test thresholds for men and women can help doctors more accurately diagnose heart attacks. Current tests use the same cutoff for everyone, but healthy women naturally have lower troponin levels than men, which may lead to missed …

This study tested whether a decision rule, which includes a quick blood test for heart damage, can help general practitioners safely decide which patients with chest pain need to go to the hospital. About 946 adults with new chest pain took part. The goal was to reduce unnecessar…

This study tested whether a physical activity program delivered by mail and phone could help older women prevent serious health problems like heart attacks, strokes, hip fractures, and falls. About 50,000 women already in the Women's Health Initiative took part. The program provi…

This study tested whether having a 'patient partner' (a fellow heart attack survivor) alongside a healthcare professional helps people stay physically active after cardiac rehab. 84 adults who had a heart attack and completed phase 2 rehab were split into two groups. One group go…

This study looked at whether an 8-week telephone stress management program could lower stress and improve quality of life in women who recently had a heart attack. 153 women with high stress levels were randomly assigned to either the stress program or usual care. The main goal w…

This study looked at 21 people who had a heart attack to see how inflammation in the body relates to heart damage seen on MRI scans. Researchers measured specific inflammation markers in the blood and compared them to MRI images taken a week later. The goal was to better understa…

This study looked at 12,500 cancer patients who had a mild heart attack (non-ST elevation MI). Researchers compared those who got invasive procedures like stents or bypass surgery with those who got only medications. The goal was to see which approach led to fewer deaths in the h…

This study looked at two methods for assigning care coordinators to older adults (65+) who have heart disease or related risks like diabetes or high blood pressure. The goal was to see which method better prevents emergency room visits and hospital stays. Researchers compared ass…

This study aimed to find out if silent myocardial ischemia—a condition where the heart doesn't get enough blood without causing chest pain—raises the risk of heart-related death or problems in people with coronary heart disease. Researchers followed patients for one to three year…

This study tracked over 11,000 COVID-19 patients to find out how often they develop dangerous blood clots in arteries or veins. Researchers looked at risk factors, treatments, and outcomes like heart attack, stroke, or death. The goal was to better understand and prevent these co…

This study looked at 362 adults who had a heart attack to find out why they delayed going to the hospital. Researchers collected information on medical history, symptoms, and barriers like lack of awareness or transportation issues. The goal is to help doctors improve care and re…

This study looked at 982 people who had a heart attack to see if things like air pollution, noise, and nearby parks or water affect their recovery over one year. Researchers used home addresses to measure environmental exposures. The goal was to understand how these factors influ…

This study tested whether a heart rehab program that mixes video calls, home exercises, and a few clinic visits works for people who survived a heart attack. Only 10 people took part, and the program was cut short due to a technology change. The goal was to see if such a program …

This study looked at 80 people who had a heart attack but no major blockages in their heart arteries (called MINOCA). Researchers checked if the ratio of white blood cells to a platelet marker in their blood could predict heart problems in the short term after leaving the hospita…

This study tested new MRI methods to better detect bleeding inside the heart muscle after a heart attack. Researchers studied 14 adults who had a heart attack to see if these scans could map the bleeding more clearly than standard MRI. The goal is to help doctors identify patient…

This study looked at 100 people who had a heart attack to see if certain markers of inflammation in the blood could predict who might die or develop heart failure within 6 months. Researchers measured these markers at several time points after the attack. The goal was to better u…

This study looked at whether taking acetaminophen (like Tylenol) at the same time as aspirin could reduce aspirin's ability to prevent heart attacks. 55 healthy adults and smokers participated. Researchers measured blood clotting markers to see if the order of taking these medici…

This study looked for genetic clues that might explain why some people develop a complication called 'no-reflow' after a heart attack procedure. In this condition, blood flow to the heart muscle is still blocked even after the main artery is opened. Researchers studied 80 heart a…