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Silent heart danger: can painless ischemia predict heart attacks?

NCT ID NCT00005216

Knowledge-focused Sponsor: University of Rochester Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether silent myocardial ischemia (reduced blood flow to the heart without chest pain) increases the risk of heart problems or death in people with coronary heart disease. Researchers followed participants for one to three years. The goal was to better understand how to predict and prevent serious heart events.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors identify which patients with coronary heart disease are at higher risk for heart attacks or death, even without chest pain.
What could go wrong
This is an observational study, not a treatment trial. It can show links but cannot prove cause and effect. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Start date

Apr 1988

Completion date

Dec 1994

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

0 to 100 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

No eligibility criteria

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Conditions

The condition(s) this trial relates to.

Arrhythmias, Cardiac cardiac rhythm disease cardiovascular disorder coronary artery disorder Coronary Disease heart disorder intermediate coronary syndrome myocardial infarction myocardial ischemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Angina, unstable Arrhythmia Cardiovascular diseases Coronary disease Heart diseases Myocardial infarction Myocardial ischemia

More trials for these conditions

Other studies related to the condition(s) this trial covers.