ISCHEMIC STROKE

This study looks at whether a simple genetic test can help doctors pick the right blood thinner for stroke patients. About 350 people who had a mild stroke or mini-stroke will be randomly assigned to either standard care or genetic testing. Those with a gene change that makes clo…

This study compares two ways to perform carotid artery stenting—a procedure to open narrowed neck arteries and prevent strokes. One method uses the wrist (radial artery), the other the groin (femoral artery). Researchers will track complications like stroke, heart attack, or majo…

This study tests whether stroke survivors can improve arm function by pairing vagus nerve stimulation with rehabilitation therapy at home. Fifty adults who have already received a Vivistim implant will work with a mobile therapist for up to 36 hours over 18 weeks. The goal is to …

This early-stage study tests whether a combination of a special liquid (conditioned medium) given through the nose plus umbilical cord stem cells injected into the brain can help repair damage from a recent ischemic stroke. The study involves 15 adults aged 25-60 with moderate to…

This study tests whether adding spironolactone to standard blood pressure treatment helps stroke survivors lower their blood pressure more effectively. About 160 adults who had a stroke will use a home blood pressure cuff to track results over 3 months. The goal is to find a bett…

This study tests a special device called Tigertriever 13 to remove blood clots from small brain arteries in people who have had a stroke. The goal is to see if using this device within 24 hours of stroke onset can safely restore blood flow better than standard medical care. About…

This study tests whether a lower blood pressure target than the current standard can reduce major heart problems and strokes in people who have already had a stroke. About 4,300 participants will be randomly assigned to either intensive or standard blood pressure control and foll…

This early-stage study tests whether briefly raising blood pressure can slow brain damage in people having a major stroke while they undergo a procedure to remove a clot. About 40 adults will take part. The goal is to see if this approach is safe and possible, not yet to prove it…

This study looks at whether using a CPAP machine to treat sleep apnea soon after an ischemic stroke can reduce the risk of another stroke, heart attack, or death within 6 months. About 3,000 adults who had a stroke and have sleep apnea are taking part. The goal is to see if this …

This early-stage study tests a new drug called NCS-01 in 16 people who have had a stroke. The goal is to see if the drug is safe and tolerable when given within 48 hours of stroke onset. Researchers will monitor side effects and changes in neurological function.

This study tests whether wearable heart monitors can find hidden atrial fibrillation (an irregular heartbeat) in people who recently had a stroke. About 337 participants will use either a short-term continuous patch or a long-term intermittent device to see which detects more cas…

This study tests whether regular physical exercise can prevent future strokes in people with narrowed arteries in the brain (symptomatic intracranial arterial stenosis). About 1,300 participants who recently had a stroke or mini-stroke will be assigned to an exercise program or u…

This study tests whether closing the left atrial appendage (a small pouch in the heart) during heart surgery can prevent strokes in people who have risk factors for atrial fibrillation and stroke. Over 6,500 adults are taking part. The main goal is to see if this procedure reduce…

This early-phase study tests whether memantine, a drug used for Alzheimer's, can improve arm and leg function in people who recently had a stroke. Twenty participants with arm weakness will be randomly assigned to receive memantine or a placebo. The study measures motor recovery …

This study tests a new wireless device that sends small electrical pulses to the vagus nerve during physical therapy. The goal is to see if it safely helps people who had a stroke at least a year ago improve movement and feeling in their affected arm and hand. About 42 adults age…

This study tests whether taking vitamin K2 supplements for one year can improve muscle strength, muscle mass, and brain function in people who recently had an ischemic stroke. About 190 participants will receive either vitamin K2 or a placebo daily. Researchers will track their p…

This study explores whether a new program called PA-ChatS can help people become more physically active within the first 6 weeks after a stroke. About 25 participants will wear a Fitbit to track steps and meet weekly with an occupational therapist. The goal is to see if people st…

This study is creating a large collection of blood samples and medical information from 72 people in Florida who have various brain blood vessel diseases, such as stroke or dementia. The goal is to build a resource that scientists can use in future research to better understand t…

This study looks at whether a lighter sedation (sedoanalgesia) or general anesthesia leads to better early brain recovery in people having emergency clot removal after a stroke. About 62 patients with severe strokes will be monitored for neurological scores and vital signs during…

This study looks at whether bacteria living in your gut and mouth are connected to the risk of stroke in people with narrowed neck arteries. Researchers will measure certain waste products from these bacteria in the blood and track who later has a stroke or worsening artery block…

This study looks at whether today's best medications—like statins and newer blood thinners—can keep stroke risk low in people with a narrowed carotid artery who have already had a minor stroke or warning signs. About 114 participants are being followed for one year to see if the …

This study tests whether a smartwatch (Apple Watch or PulseOn) can detect hidden atrial fibrillation (AF) in 84 stroke patients who already have an implanted heart monitor. Participants wear the watch for 12 weeks, and the watch alerts them if it senses an irregular pulse, allowi…