Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Exercise prescription: a new weapon against stroke?

NCT ID NCT06615726

Prevention Sponsor: Capital Medical University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests whether adding regular, personalized exercise to standard medical care can prevent new strokes in 1300 people with symptomatic intracranial arterial stenosis (narrowed arteries in the brain). Participants are randomly assigned to either standard care or standard care plus a tailored aerobic exercise plan guided by an expert. The main goal is to see if exercise reduces the number of new ischemic strokes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
regular physical exercise
What this could lead to
If successful, this could show that a structured exercise program significantly reduces the risk of another stroke in people with narrowed brain arteries.
What could go wrong
This is an open-label trial, so participants know they are exercising, which can bias results. Exercise may not be enough to prevent strokes in this high-risk group, and adherence to the program may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 1,300 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2024

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

1\. Inclusion criteria: 1. Age ≥40 years and ≤80 years; 2. Ischemic stroke or TIA (transient ischemic attack) onset ≤30 days; 3. Ischemic stroke or TIA is attributed to 50-99% of the ICAS (internal carotid artery, M1 segment of middle cerebral artery, M2 segment of middle cerebral artery, basilar artery, or vertebral artery; the degree of stenosis is determined by magnetic resonance angiography, computed tomography angiography, digital subtraction angiography using the standards of warfarin-aspirin symptomatic intracranial disease ); 4. mRS (modified Rankin Scale)≤4; 5. The patient himself or his legal representative signs the informed consent form. 2\. Exclusion criteria: 1. Stroke progression within the past 3 days (defined as an increase in the score of National Institute of Health Stroke Scale ≥4 points or an increase in individual items of ≥2 points). 2. mRS≥1 before the stroke onset. 3. Concurrent osteoarthritis, fracture, lower limb venous thrombosis, unstable angina pectoris, respiratory diseases, limb disabilities, etc., making it theoretically difficult to cooperate with the physical activity plan for this trial. 4. Complicated with motor disorders such as Parkinson\'s disease and Parkinson\'s syndrome. 5. The vessels responsible for this stroke had tandem lesions (more than 50% of extracranial artery stenosis). 6. The vessel responsible for this stroke has undergone intracranial balloon angioplasty and/or stent implantation (except for mechanical thrombectomy and/or aspiration alone). 7. It is expected that intracranial arterial balloon angioplasty and/or stent implantation will be performed on the vessel responsible for the stroke within 3 months. 8. Patients who exercised regularly within the last 6 months. Regular exercise is defined as four or more moderate intensity exercises per week for more than 10 minutes each time or two or more high intensity exercises per week for more than 10 minutes each time. 9. Inability to understand and/or comply with the trial procedures and/or follow-up due to mental illness, cognitive or emotional disorders. 10. Life expectancy is less than one year. 11. Women who are known to be pregnant or nursing, or have a positive pregnancy test; 12. Are participating in other drug or device research. 13. There are other circumstances that investigators consider are not suitable for enrollment.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Ischemic stroke are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

cerebral artery stenosis ischemic stroke transient ischemic attack

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ischemic stroke Transient ischemic attack

Contacts and locations

Locations

  • Affiliated Hospital of Inner Mongolia University for Nationalities

    Tongliao, Neimenggu, China

  • Affiliated Hospital of Shandong Second Medical University

    Weifang, Shandong, China

  • Army Military Medical University Officer School affiliated hospital

    Shijiazhuang, Hebei, China

  • Beijing Pinggu District Hospital

    Beijing, Beijing Municipality, China

  • Brain Hospital Affiliated to Guangzhou Medical University

    Guangzhou, Guangdong, China

  • Cangzhou People's Hospital of integrated Chinese and Western Medicine, Hebei Province

    Cangzhou, Hebei, China

  • Chongqing Sanbo Jiangling Hospital

    Chongqing, Chongqing Municipality, China

  • Fangcheng County People's Hospital

    Nanyang, Henan, China

  • Foshan Fifth People's Hospital

    Foshan, Guangdong, China

  • Foshan Nanhai District Sixth People's Hospital

    Foshan, Guangdong, China

  • Gongyi Xinhua Hospital of Traditional Chinese Medicine

    Gongyi, Henan, China

  • Henan Provincial People's Hospital

    Zhengzhou, Henan, China

  • Hospital 925, Joint Logistics Support Force

    Guizhou, Guiyang, China

  • Huainan Sunshine Xinkang Hospital

    Huainan, Anhui, China

  • Hubei Third People's Hospital

    Wuhan, Hubei, China

  • Jianyang City Hospital of Traditional Chinese Medicine

    Jiancheng, Sichuan, China

  • Jilin City People's Hospital

    Jilin City, Jilin, China

  • Jinan High-tech East District Hospital

    Jinan, Shandong, China

  • Jiujiang First People's Hospital

    Jiujiang, Jiangxi, China

  • Laixi People's Hospital

    Laixi, Shandong, China

  • Lanshan District People's Hospital

    Rizhao, Shandong, China

  • Liaocheng People's Hospital

    Liaocheng, Shandong, China

  • Lichuan Ethnic Chinese Medicine Hospital

    Lichuan, Hubei, China

  • Liuyang City Jili Hospital

    Guankou, Hunan, 410300, China

  • Longchuan Hospital of Traditional Chinese Medicine

    Heyuan, Guangdong, China

  • Nanyang City Center Hospital

    Nanyang, Henan, China

  • Ningjin County Hospital

    Xingtai, Hebei, China

  • Ningjin County People's Hospital

    Dezhou, Shangdong, China

  • Shandong University Qilu Hospital Dezhou Hospital

    Dezhou, Shandong, China

  • Shanghai Hechuan Rhein Hospital of Traditional Chinese Medicine

    Shanghai, Shanghai Municipality, China

  • Shangqiu First People's Hospital

    Shangqiu, Henan, China

  • Shengli Oilfield Central Hospital

    Dongying, Shandong, China

  • Shihezi People's Hospital

    Shihezi, Xinjiang, 836800, China

  • Sichuan Academy of Sciences Hospital

    Chengdu, Sichuan, China

  • Suzhou Municipal Hospital

    Suzhou, Anhui, 234000, China

  • Taihe Hospital of Traditional Chinese Medicine

    Fuyang, Anhui, China

  • Tangshan Workers' Hospital

    Tangshan, Hebei, China

  • Tengzhou Central Hospital

    Zaozhuang, Shandong, China

  • The First Affiliated Hospital of Henan University of Chinese Medicine

    Zhengzhou, Henan, China

  • The First Affiliated Hospital of Xinxiang Medical College

    Xinxiang, Henan, China

  • The First Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, 450000, China

  • The Second People's Hospital of Wuhu

    Wuhu, Anhui, China

  • Tongxu First Hospital

    Kaifeng, Henan, China

  • Xiangtan Central Hospital

    Xiangtan, Hunan, China

  • Xihua County People's Hospital

    Zhoukou, Henan, China

  • Xinmin People's Hospital

    Shenyang, Liaoning, China

  • Xuanwu Hospital, Capital Medical University

    Beijing, Beijing Municipality, 100053, China

  • Ya 'an People's Hospital

    Yaan, Sichuan, China

  • Yantai Fushan District People's Hospital

    Yantai, Shandong, China

  • Yantai Yeda Hospital

    Yantai, Shaanxi, China

  • Yongcheng Central Hospital

    Shangqiu, Henan, China

  • Yongjia County People's Hospital

    Wenzhou, Zhejiang, China

  • Yueqing People's Hospital

    Wenzhou, Zhejiang, China

  • Yueyang City People's Court

    Yueyang, Hubei, China

  • Zhangzhou Hospital

    Zhangzhou, Fu, China

  • Zhengzhou First People's Hospital

    Zhengzhou, Henan, China

  • Zhengzhou Zhongkang Hospital

    Zhengzhou, Henan, China

  • Zhongmou County People's Hospital

    Zhengzhou, Henan, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.