Vitamin K2 supplement shows promise for stroke recovery in new trial
NCT ID NCT06817512
First seen Jun 27, 2026 · Last updated Sep 09, 2026 · Updated 2 times
Summary
This study tests whether taking vitamin K2 supplements for one year can improve muscle strength and brain function in people who recently had an ischemic stroke. 190 participants will receive either vitamin K2 or a placebo daily. Researchers will measure handgrip strength and other outcomes over 12 months, with an additional year of follow-up.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Vitamin K2 (MK-7) supplement
- What this could lead to
- If it works, this could point toward a simple, safe supplement to help people regain muscle and brain function after a stroke.
- What could go wrong
- This is a small, early-stage trial with no phase designation. The supplement may show no benefit over placebo, and results may not apply to all stroke patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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190 people
The number who actually took part.
- Started
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Mar 2025
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Participants who meet all the following conditions will be included in the trial: 1. Men or women aged ≥ 18 years. 2. Patients with recent ischemic stroke(first or recurrent stroke no more than 7 days before admission)without significant residual limb paralysis, NIHSS score between 2-15, and muscle strength graded 2-4. 3. The patient and their legal guardian (or legally acceptable representative) voluntarily sign the informed consent form. Exclusion Criteria: Participants who meet any of the following conditions will be excluded from the trial: 1. Presence of consciousness disorders, aphasia, or swallowing disorders. 2. The diagnosis or suspicion of cerebral hemorrhage, atrial fibrillation, or other factors leading to cardiogenic cerebral infarction. 3. Coagulation dysfunction or use of vitamin K antagonists. 4. Suffering from chronic gastrointestinal malabsorption (such as celiac disease, short bowel syndrome), severe congestive heart failure, malignant hypertension, severe liver and kidney dysfunction, persistent malignant tumors (continuous treatment, or diagnosis of malignant tumors\<5 years), or other related diseases considered by researchers that seriously affect the patient's survival. 5. Having musculoskeletal diseases or cognitive impairment before the stroke. 6. Currently using or planning to use non research approved dietary supplements during the study period. 7. Currently using or planning to use drugs that affect cognitive or neurological function during the research period. 8. Restricted normal eating or currently receiving enteral or parenteral nutrition support. 9. Contraindications for MRI and other examinations. 10. Currently pregnant or planning pregnancy, currently breastfeeding. 11. Participated in a clinical trial using experimental drugs or devices within the past 3 months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hongqi Hospital Affiliated to Mudanjiang Medical University
Mudanjiang, Heilongjiang, 157000, China
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The First Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, 150001, China
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The Second Affiliated Hospital of Qiqihar Medical University
Qiqihar, Heilongjiang, 161006, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Blood test may reveal who recovers after a stroke
- Can a smart bracelet and app stop a second stroke?
- Pharmacist and coach team takes aim at blood pressure after stroke