INFLAMMATORY BOWEL DISEASES

This study tested whether adding atorvastatin, a common cholesterol-lowering drug, to the standard treatment mesalamine can improve quality of life and reduce inflammation in adults with mild-to-moderate ulcerative colitis. 54 participants completed the trial, which measured chan…

This study tested whether a blood test measuring proteins can help doctors choose a more powerful treatment early for people newly diagnosed with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. 300 patients were split into two groups: one where…

This study tested whether adding a drug called bezlotoxumab to a fecal microbiota transplant (FMT) could better prevent repeat Clostridium difficile infections in people with inflammatory bowel disease (IBD). About 61 adults with at least two past C. diff infections took part. Th…

This study looked at 688 people in South Korea with ulcerative colitis or Crohn's disease who were treated with Kynteles (vedolizumab) as part of their regular care. The main goal was to track side effects and see how many patients felt better after treatment. The results help do…

This study tested an experimental drug called MORF-057 in 39 adults with moderate-to-severe ulcerative colitis, a chronic inflammatory bowel disease. The goal was to see if the drug could reduce gut inflammation and improve symptoms over 12 weeks. Participants took the drug by mo…

This study tested whether transplanting healthy donor stool into the gut could help people with ulcerative colitis (UC), a chronic inflammatory bowel disease. 102 participants with mild-to-moderate UC received fecal microbiota transplantation (FMT) from different donors. The goal…

This study looked at whether adding the antibiotic minocycline to standard mesalamine therapy can better control ulcerative colitis, a chronic inflammatory bowel disease. Forty-six adults with mild to moderate UC took part. The main goal was to measure changes in disease activity…

This study looked at whether giving nutrition through a small vein in the arm (peripheral parenteral nutrition) helps patients recover better after colorectal surgery. The trial included 200 adults who had surgery for conditions like colorectal cancer or inflammatory bowel diseas…

This study looked for new blood markers to help diagnose inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. Researchers measured four specific proteins in 70 newly diagnosed patients before and after treatment. The goal was to find a simple, nonin…

This study tested whether an 8-week dietary program called Tasty & Healthy could lower signs of gut inflammation in 29 healthy first-degree relatives of people with Crohn's disease. Participants were at higher risk based on genetic and biological markers. The main goal was to see…

This study looked at whether a short-term, plant-based low-calorie diet (called a fasting mimicking diet) could improve depressive symptoms in people with inflammatory bowel disease (IBD). 42 adults with IBD and mild-to-moderate depression completed three 5-day diet cycles. Resea…

This small study tested whether an AI-powered virtual reality app could safely help people with inflammatory bowel disease (IBD) who also have mild to moderate anxiety or depression. Twenty-two adults with IBD used the app during a single session. The goal was to see if the appro…

This study tested whether ondansetron, a common nausea medicine, helps children aged 2 to 20 tolerate the bowel preparation needed before a colonoscopy. Researchers measured how clean the bowel was and how much pain, bloating, nausea, and vomiting the children felt. The goal was …

This study looked at whether eating gluten-free for one week can reduce stomach symptoms and tiredness in people with ulcerative colitis. Fifteen adults with the condition ate a gluten-free diet plus special granola bars—first without gluten, then with high gluten. They reported …

This study tested a self-management program for people with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. The program included eight sessions covering topics like symptom tracking, relaxation, diet, and pain management. Researchers wanted to …

This early-stage study tested a new oral drug, IPG11406, in 66 healthy adults to see if it is safe and how the body processes it. Participants received either the drug or a placebo. This research does not treat any disease but is a necessary first step before testing the drug in …

This study looked at 211 adults with long-standing inflammatory bowel disease (IBD) to see which colonoscopy method finds precancerous growths better: high-definition white light or dye spraying. Participants had IBD for at least 8 years and were getting a routine screening. The …

This study looked at physical fitness in 100 children and teens (ages 10-17) with chronic inflammatory bowel disease (Crohn's disease, ulcerative colitis, or unclassified colitis) and compared them to healthy kids of the same age, weight, and sex. Researchers measured cardiorespi…

This study took small tissue samples from the intestines of 110 people with inflammatory bowel disease (Crohn's or ulcerative colitis), familial polyposis, or healthy controls. Researchers grew these samples into mini-organs called organoids to study how intestinal stem cells beh…

This study looked at how inflammatory bowel disease (IBD) impacts oral health and daily life. Researchers compared 138 adults with IBD to people without IBD, using a questionnaire to measure oral health-related quality of life. The goal was to identify factors like medications or…

This study looked at how menstrual cycles and hormonal birth control affect symptoms in women with inflammatory bowel disease (IBD). Researchers surveyed 50 women to understand their preferences for birth control methods and whether they would join a future trial. The goal is to …

This study looked at over 8,700 pregnant women with inflammatory bowel disease (Crohn's or colitis) to see how well doctors follow guidelines when using antiTNFα drugs during pregnancy. Researchers checked for complications in both mothers and babies up to one year after birth. T…

This study took small tissue samples from 16 people with or without inflammatory bowel disease during routine colonoscopies. Researchers grew these samples into mini-organs called organoids in the lab. They then tested how radiation and potential treatments affect these organoids…

This study aimed to create a tool to help nurses assess and care for the sexual health needs of men with inflammatory bowel disease (IBD). Researchers worked with 792 participants, including men with IBD and healthcare staff, to understand current gaps and develop a practical int…

This study tested whether a transition coach could help 16-17 year olds with Juvenile Idiopathic Arthritis or Inflammatory Bowel Disease move from pediatric to adult healthcare. 27 teens took part in a coaching program to build self-management skills. The main goal was to see if …

This study observed 92 adults with Crohn's disease or ulcerative colitis who were already taking or starting vedolizumab. Researchers watched whether patients chose intravenous infusions at a clinic or injections at home, and how long they stayed on their chosen treatment. The go…

This study looked at 40 children aged 6 to 17 with inflammatory bowel disease (IBD) to understand how DNA that escapes from cells might worsen inflammation. Researchers analyzed blood, stool, and gut tissue samples to study a specific pathway called cGAS-STING. The goal was to id…

This study looked at the gut bacteria of 15 people with inflammatory bowel disease (IBD) or Parkinson's disease and compared them to healthy individuals. Researchers collected stool and blood samples to see which bacteria were present and whether bacteria were leaking from the gu…