INFLAMMATORY BOWEL DISEASES

This study tested whether using a blood protein test to identify patients with inflammatory bowel disease (IBD) at high risk for severe disease could improve their outcomes. Newly diagnosed patients were randomly assigned to either have their treatment guided by this test or rece…

This study monitored patients in South Korea with ulcerative colitis or Crohn's disease who were treated with vedolizumab (Kynteles) as part of their regular care. The main goal was to check for side effects and see how many patients' symptoms improved while using the drug. It ai…

This study tested whether adding the antibiotic minocycline to standard mesalamine treatment could better control ulcerative colitis, a chronic inflammatory bowel disease. Researchers enrolled 46 adults with mild-to-moderate disease who were already taking mesalamine. They measur…

This study tested an oral drug called MORF-057 in 39 adults with moderate to severe ulcerative colitis, a chronic inflammatory bowel disease. The main goal was to see if the drug was safe, tolerable, and could reduce disease activity over 12 weeks of treatment. Participants who c…

This study investigated whether the background of a fecal transplant donor affects treatment success for ulcerative colitis, a chronic gut disease. Researchers compared transplants from donors of Han and Bai ethnicities to see if one led to better control of the disease. The goal…

This study tested whether adding a common cholesterol-lowering drug (atorvastatin) to standard mesalamine treatment could better control ulcerative colitis. It involved 54 adults with mild-to-moderate disease who were not on strong immunosuppressants. Researchers measured if the …

This study tested if adding a drug called bezlotoxumab to a fecal microbiota transplant (FMT) works better than FMT alone to prevent C. difficile infection (CDI) from coming back. It involved 61 adults with inflammatory bowel disease (IBD) who kept getting repeat CDI. Participant…

This study tested a safer way to give IV nutrition to patients recovering from colon surgery. Researchers wanted to see if giving nutrition through a regular arm IV (instead of a deep chest line) could help patients heal better and avoid complications. They enrolled 200 patients …

This study compared two standard colonoscopy techniques used to screen for colon cancer in people who have had inflammatory bowel disease (IBD) for eight years or more. Researchers tested whether high-definition white-light colonoscopy works as well as dye-spraying colonoscopy at…

This study aimed to find better blood tests to diagnose inflammatory bowel diseases (IBD), like Crohn's disease and ulcerative colitis. Researchers measured four specific proteins in the blood of 70 newly diagnosed, untreated patients. The goal was to see if these proteins could …

This study tested whether following a specific 'Tasty & Healthy' diet for 8 weeks could lower biological markers associated with the future risk of developing Crohn's disease. It involved 29 healthy people who were close relatives of someone with Crohn's and had elevated risk mar…

This study tested a new coaching program to help teenagers with juvenile arthritis or inflammatory bowel disease (IBD) move from pediatric to adult healthcare. Researchers wanted to see if the program was practical to run and if it helped young people feel more confident managing…

This study tested whether adding the anti-nausea medication ondansetron (Zofran) to standard bowel prep helps children complete their colonoscopy preparation more comfortably and effectively. Researchers compared children using just laxatives to those using laxatives plus ondanse…

This study tested whether a special plant-based, low-calorie 'fasting mimicking' diet could reduce depression symptoms in people with Crohn's disease or ulcerative colitis. 42 adult participants with mild depression tried three cycles of the 5-day diet, followed by normal eating.…

This study tested whether eating a gluten-free diet could reduce gut symptoms and fatigue in people with ulcerative colitis. Fifteen participants tried two different diets for one week each: one with high gluten and one completely gluten-free. Researchers measured their symptoms …

This small, exploratory study tested a single session using a virtual reality app with an AI-powered guide to provide mental health support. It involved 22 adults with inflammatory bowel disease (IBD) who also had mild to moderate anxiety or depression. The main goal was to see i…

This study tested a new self-management program designed to help people with Crohn's disease or ulcerative colitis. The program taught 55 participants strategies for tracking symptoms, managing stress and pain, improving sleep, and adjusting diet. Researchers wanted to see if the…

This study observed how 92 Swiss adults with Crohn's disease or ulcerative colitis used vedolizumab medication in real-world clinic settings. Researchers tracked whether patients received the drug through IV infusions or under-the-skin injections, and monitored how long they stay…

This study aimed to understand how gut bacteria differ in people with Inflammatory Bowel Disease (IBD) or Parkinson's Disease compared to healthy people. Researchers collected stool and blood samples from 15 participants to look for specific bacteria and see if any had moved from…

This study aimed to better understand the root causes of inflammatory bowel diseases (like Crohn's and colitis) and a genetic condition called familial adenomatous polyposis. Researchers grew tiny 3D models of the intestine, called 'organoids,' from tissue samples of 110 patients…

This study aimed to understand how oral health problems affect the daily life and well-being of people with Crohn's disease or ulcerative colitis. Researchers compared survey responses from 138 adults with IBD to people without IBD. The goal was to identify factors, like medicati…

This study aimed to understand why inflammatory bowel diseases (IBD) like Crohn's and colitis are often more severe in children. Researchers tested the idea that DNA leaking from cells might trigger and worsen gut inflammation through a specific biological pathway. They analyzed …

This study aimed to create a new lab tool for developing future treatments. Researchers took tiny tissue samples from patients with inflammatory bowel disease (IBD) and healthy people during routine colonoscopies. They grew these samples into 3D 'mini-guts' (organoids) in the lab…

This study looked at the safety of anti-TNF medications for pregnant women with inflammatory bowel diseases (IBD) like Crohn's disease and ulcerative colitis. Researchers analyzed French national health data from over 8,700 pregnancies to understand whether these medications help…