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Poop transplant plus drug shows promise against recurrent c. diff in IBD patients

NCT ID NCT03829475

First seen Jan 04, 2026 · Last updated May 23, 2026 · Updated 22 times

Summary

This study tested whether adding a drug called bezlotoxumab to a fecal microbiota transplant (FMT) could better prevent repeat Clostridium difficile infections in people with inflammatory bowel disease (IBD). About 61 adults with at least two past C. diff infections took part. They received either FMT plus bezlotoxumab or FMT plus a placebo, and were followed for 3 months to see if the infection came back.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.