INFLAMMATORY BOWEL DISEASES

This study tests a device that filters inflammatory substances from the blood during flare-ups of Crohn's disease or ulcerative colitis. About 40 adults will either receive standard care alone or standard care plus the Efferon LPS filter. The goal is to see if the filter safely r…

This study tests whether xylitol, a common sweetener, can safely clear C. difficile bacteria from the gut in people with inflammatory bowel disease (IBD). About 99 adults with mild or inactive IBD will take either a low or high dose of xylitol or a placebo for four weeks. Researc…

This study tests a new drug called ATH-063 in people with moderate to severe ulcerative colitis who have not improved with other advanced treatments. The goal is to see if the drug can reduce symptoms like diarrhea and bleeding and help the gut heal. About 120 adults will receive…

This study tests a one-day acceptance and commitment therapy (ACT) program designed for veterans with inflammatory bowel disease (IBD) and mental health conditions like depression or anxiety. The goal is to see if this brief therapy is practical and helpful for improving quality …

This study tests a self-management program for people with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. The goal is to see if changing behaviors can improve health and quality of life. About 40 adults with active IBD will take part in the pr…

This study tests whether neurofeedback, a type of brain training, can reduce muscle and joint pain in people with inflammatory bowel disease (IBD). About 80 adults with IBD and chronic pain will use a special device to learn how to control their brain activity. The goal is to see…

This study tests whether duloxetine, a medication that affects brain signals, can help adults with inflammatory bowel disease (IBD) feel less distressed and disabled. About 32 adults with IBD who have high anxiety, distress, or disability will take duloxetine daily for several we…

This study tests whether a dietary supplement called GenesiDol can reduce joint and muscle pain in people with inflammatory bowel disease (IBD), like Crohn's disease or ulcerative colitis. About 40 adults with persistent pain will take the supplement for 8 weeks. The goal is to s…

This study will test if a detailed heart ultrasound (speckle tracking echocardiography) can detect early, hidden heart problems in 100 adults with inflammatory bowel disease (IBD). Researchers will compare these findings with standard heart tests and inflammation markers. The goa…

This study looks at how anxiety, depression, and stress may affect the success of advanced treatments for inflammatory bowel disease (IBD). About 450 people with IBD who are on infusion therapies will fill out questionnaires about their mental health. Researchers will then track …

This study is developing a questionnaire to measure how well people with inflammatory bowel disease (IBD) take care of themselves. Researchers will interview 275 patients to identify key self-care behaviors, then test the questionnaire's accuracy. The goal is to give doctors a be…

This study will check if certain blood platelet measurements can show how active inflammatory bowel disease (IBD) is. Researchers will compare platelet levels with standard disease activity scores in 84 adults with IBD. The goal is to see if these easy-to-get blood tests could he…

This study looks at whether low vitamin D levels are linked to more active disease in people with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. Researchers will measure vitamin D in the blood of 100 adults with IBD and compare it to their cur…

This study looks at whether anemia (low red blood cells) can help predict how Inflammatory Bowel Disease (IBD) will progress in patients. Researchers will track 83 adults with IBD at Assiut University Hospitals to see if those with anemia have higher hospitalization rates. The go…