HEALTHY VOLUNTEERS

This study is checking the safety of a high-dose flu vaccine (Efluelda) in adults aged 65 and older in South Korea. About 670 participants will receive one shot and be monitored for side effects over about a month. The goal is to confirm the vaccine is safe when used in everyday …

This early-stage study tests a new radioactive imaging agent called MeFAMP to see if it can safely and accurately detect brain tumors using PET scans. Researchers will study healthy volunteers and people with recurrent high-grade glioma or brain metastases from other cancers. The…

This study aims to prevent obesity in adolescents and young adults (ages 18-25) who are at high risk due to family history and higher starting weight. Researchers will test a program that combines lifestyle coaching with medication to target the body's energy regulation. The goal…

This study tests whether a single dose of (2R,6R)-HNK, a drug related to ketamine, can safely reduce short-term pain in healthy adults aged 18 to 60. Participants will receive either the drug, a placebo, or no treatment, and will undergo pain tests and brain scans. The goal is to…

This early-stage study tests the safety of a new drug called migaldendranib in 36 healthy adults. Participants receive weekly injections, and researchers monitor for side effects and how the drug moves through the body. The goal is to gather safety information, not to treat any d…

This early-phase study tests the safety and tolerability of KMY tablets in 120 healthy adults aged 18 to 45. Participants receive single or multiple doses, and some take the drug with a high-fat meal to see how food affects absorption. The goal is to gather safety data and unders…

This study aims to see if a simple, markerless motion capture system using only four cameras can accurately measure how children walk. Researchers will compare this new method to traditional lab-based systems in 125 healthy volunteers aged 6 to 17. If successful, the approach cou…

This study looks at whether a single dose of nicotinamide riboside (a common supplement) can change sleep patterns in healthy adults who have mild sleep troubles. Twenty volunteers will have their sleep measured overnight with and without the supplement. The goal is to see if thi…

This early-stage study tests the safety of a new drug called HS-20152 in 32 healthy adults aged 18 to 64. The drug targets the complement system, a part of the immune system. Researchers will monitor side effects and measure how the drug moves through the body. This study does no…

This study looks at whether a supplement called TRPTI (oleoylethanolamide) can change gut bacteria and blood markers related to metabolism in healthy adults. About 90 people will take either TRPTI or a placebo for 8 weeks. The main goal is to see if TRPTI lowers a substance linke…

This early-stage study tests whether liquid metformin causes fewer stomach issues than standard tablets. Twenty-four healthy adults will try single doses of two liquid strengths and one tablet, then report side effects. The goal is to see which form is better tolerated, not to tr…

This early-stage study aims to understand how the experimental drug BMS-986435 behaves in people with normal liver function compared to those with mild or moderate liver impairment. Researchers will measure drug levels in the blood and monitor safety. The study involves 24 adults…

This early-stage study looks at how a new drug called CS0159 behaves in the body when taken with a high-fat meal or with other common drugs (rifampicin and itraconazole). The goal is to understand how these factors change drug levels and safety. 32 healthy adults aged 18-45 will …

This study tests a new computer method (HDC) to recognize hand gestures from muscle signals. Ten healthy volunteers will wear a device with 32 sensors on their arm and perform gestures. The goal is to see if the new method is more accurate than existing ones. This research does n…

This study compares how people with idiopathic environmental intolerance (IEI) and healthy volunteers process bodily signals and beliefs. IEI causes symptoms like pain and fatigue without a clear physical cause. Researchers will use computer tasks and picture tests to see if diff…

This early-stage study tests an oral drug called ISM4808 in 86 healthy adults in China. The main goal is to see if the drug is safe and how the body processes it. Participants take single or multiple doses, and researchers monitor for side effects. This study does not aim to trea…

This early-stage study tests whether a new formulation of the antibiotic polymyxin B (VRP-034) is safer for the kidneys than the current version. About 48 healthy adult men will receive one or more doses of either the new or standard drug. Researchers will measure kidney injury m…

This study looks at how stimulating the vagus nerve through the ear at different speeds (frequencies) changes heart rate, blood pressure, and breathing in healthy adults aged 18 to 40. Each person will try five different stimulation settings, including a sham (fake) one, in separ…

This early-stage study looks at whether the hormone progesterone changes how muscles build protein after resistance exercise. Twenty healthy women aged 18-30 will take either progesterone pills or a placebo, then do leg exercises. Researchers will take small muscle samples to mea…

This study looks at whether Kinesio Taping can immediately improve hand and arm performance in healthy adults. 36 participants will be randomly assigned to get real Kinesio Tape, a fake (sham) tape, or no tape at all. They will then do tests like grip strength and typing to see i…

This early-stage trial tests a single dose of KL0011034 injection in 76 healthy Chinese volunteers to check its safety and how the body processes it. Participants are randomly assigned to receive the drug, a placebo, or a positive control. The study does not aim to treat any dise…

This study tests whether real-time brain imaging (fMRI) can help healthy people change how they perceive social situations. Ten volunteers will undergo six MRI sessions while watching social animations. The goal is to understand brain control, not to treat any disease.

This study tests a new technology that uses focused sound waves to stimulate specific brain areas involved in vision and hearing. Researchers will try different settings in 20 healthy adults to find the best way to trigger visual flashes or auditory tones. The goal is to better u…

This is a first-in-human study to check the safety and tolerability of a new drug called ZE74-0282. It involves 40 healthy adults aged 18 to 55 who will receive either the drug or a placebo. The main goal is to monitor side effects and how the drug moves through the body, not to …

This study looks at whether the design of a breathing mask changes how healthy people breathe while using a machine that helps with breathing (non-invasive ventilation). Ten healthy adults will try four different masks and breathe through their mouth or nose. The goal is to see i…

This study looks at how the length of heart rate recording affects results during a mild nerve stimulation in healthy adults. Forty volunteers will receive both real and fake stimulation in random order. Researchers will compare 1-minute, 5-minute, and 10-minute recordings to see…

This study looks at how different phases of the menstrual cycle relate to muscle strength and physical performance in active women aged 18-35. Participants will track their cycle with a mobile app and attend three lab visits for non-invasive tests like strength and body compositi…

This study looks at how a numbing injection near the wrist artery affects blood flow and hand temperature in 20 healthy adults. Researchers will measure these changes before and after a cold-water hand test. The goal is to better understand how the nervous system controls blood v…

This study looks at how brief periods of low oxygen (intermittent hypoxia) affect a measure called 'loop gain,' which reflects how your body controls breathing. Researchers want to know if these oxygen dips can make breathing control less stable, which may help explain sleep apne…

This study checks whether two versions of a drug (IN-M00007 and IN-R00007) are absorbed into the body the same way. About 60 healthy adults aged 19 to 59 will take a single dose of each drug at different times. The goal is to compare safety and drug levels in the blood, not to tr…

This study tests five different frequencies of vagus nerve stimulation (including a sham/placebo) in 36 healthy adults aged 18-30. Researchers measure changes in heart rate variability, blood pressure, and breathing rate to see which frequency has the strongest effect. The goal i…

This study looks at how different vibration frequencies from a smartphone app affect hand performance in healthy young adults. Twenty participants will test three vibration levels on their dominant hand, measuring grip strength, touch sensitivity, pain threshold, and reaction tim…

This study looks at whether doing sit-to-stand exercises with a blood flow restriction cuff on the legs can improve back muscle endurance and balance better than the same exercises without the cuff. The study involves 70 healthy adults aged 20-25 who will exercise twice a week fo…

This study is an early-stage trial to check the safety of a new drug called VV913 in healthy Chinese men aged 18 to 45. It involves giving multiple doses of the drug or a placebo to see how the body handles it and if any side effects occur. The goal is to gather safety and drug-l…

This early-stage study tests two different liquid forms of metformin against the usual tablet in 24 healthy adults. Researchers will measure blood sugar levels over a few hours to see how the liquid versions compare. The goal is to gather information, not to treat any disease.

This study looks at how Hezkue® oral sildenafil suspension behaves in the body after moderate alcohol consumption. Twenty-four healthy adults will take the medication under controlled conditions. Researchers will measure drug levels in the blood and how quickly participants feel …

This early-stage study tests a new type of brain stimulation called high-density theta burst stimulation (hdTBS) in 35 healthy adults aged 22 to 60. The goal is to check if it is safe and to see how it affects brain activity compared to standard stimulation. Participants will hav…

This study will test three different portable inhaler devices in 10 healthy adults. Each person will try all three devices in random order. The goal is to see how well the devices control airflow, record breaths, and feel comfortable to use. No medicine is involved—only a salt-ba…

This study looks at how stimulating a nerve in the ear for different amounts of time (5, 10, or 15 minutes) changes heart rate, blood pressure, and breathing in healthy adults. 44 volunteers will receive either real or fake stimulation. The goal is to understand if longer stimula…