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Could a ketamine cousin replace opioids for pain?

NCT ID NCT07504601

First seen Apr 02, 2026 · Last updated May 23, 2026 · Updated 9 times

Summary

This study tests whether a single dose of (2R,6R)-HNK, a drug related to ketamine, can safely reduce short-term pain in healthy adults aged 18 to 60. Participants will receive either the drug, a placebo, or no treatment, and will undergo pain tests and brain scans. The goal is to find a non-addictive alternative to opioids for acute pain.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.