National Center For Complementary And Integrative Health (nccih)

This study aims to understand the different types of fatigue people experience, whether from cancer, lupus, ME/CFS, or other conditions. Researchers will compare fatigued and non-fatigued adults using interviews, questionnaires, physical tests, and optional brain scans. The goal …

This study tests if mild electrical stimulation of the left ear can change how healthy adults perceive pain. Researchers will compare stimulation of a nerve-rich area versus a non-nerve area. Participants will rate pain from heat on their arm and complete mood questionnaires over…

This study looks at how social and cultural factors affect how people express pain and how others judge that pain. Researchers will measure pain responses in healthy volunteers and then test whether observers can accurately estimate someone else's pain. The goal is to understand …

This study aims to better understand pain by examining people with and without pain disorders. Researchers will expose participants to pleasant and unpleasant sensations, like heat, cold, or pressure, and collect health information through exams, questionnaires, and MRI scans. Th…

This study looks at how nerves send signals in people with PIEZO2 Deficiency Syndrome (PDS), a rare genetic condition that reduces the ability to feel touch and pain. Researchers will compare nerve activity in 16 adults (some with PDS, some healthy) using tiny needles and various…

This study aims to understand how psychological factors, such as expectations and emotions, influence the way we perceive pain. Healthy volunteers aged 18-50 will undergo brain scans (MRI) and pain tests (heat or electric shocks) while their heart rate, breathing, and other respo…