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Rare gene disorder study probes nerve signals

NCT ID NCT06052631

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 34 times

Summary

This study looks at how nerves send signals in people with PIEZO2 Deficiency Syndrome (PDS), a rare genetic condition that reduces the ability to feel touch and pain. Researchers will compare nerve activity in 16 adults (some with PDS, some healthy) using tiny needles and various sensations like brushing, heat, and pinching. The goal is to better understand how PDS changes nerve function, not to test a treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.