Rare gene Disorder's nerve secrets revealed in tiny needle test

NCT ID NCT06052631

First seen Nov 01, 2025 · Last updated May 03, 2026 · Updated 33 times

Summary

This study looks at how nerves send signals in people with PIEZO2 Deficiency Syndrome (PDS), a rare genetic condition that reduces the ability to feel touch and pain. Researchers will use tiny needles to record nerve activity while applying gentle sensations like brushing, heat, or pinching. The goal is to compare nerve responses between 16 adults with PDS and healthy volunteers to better understand the disorder.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.