National Center For Complementary And Integrative Health (nccih)
Clinical trials sponsored by National Center For Complementary And Integrative Health (nccih), explained in plain language.
Upcoming readouts
Trials from this sponsor expected to report results within the next 12 months.
- Tiny needles probe rare gene disorder that blocks touch Results expected Dec 2026 (estimated)
- NIH launches massive pain study to unravel mysteries of discomfort Results expected Feb 2027 (estimated)
- Scientists probe Brain's pain matrix in healthy volunteers Results expected Feb 2027 (estimated)
- Can we fix pain bias? new study investigates Results expected May 2027 (estimated)
- Fatigue study seeks to unravel mystery of exhaustion Results expected Jun 2027 (estimated)
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Could a ketamine metabolite replace opioids for acute pain?
Symptom relief Not yet recruitingThis Phase 2 trial tests whether a single dose of (2R,6R)-hydroxynorketamine (HNK), a non-addictive ketamine metabolite, can reduce acute pain in 92 healthy adults. Participants receive either HNK or a placebo intravenously and undergo pain tests, brain scans, and safety monitori…
Phase 2 • Sponsor: National Center for Complementary and Integrative Health (NCCIH) • Aim: Symptom relief
Last updated Sep 21, 2026 18:00 UTC
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New pain test battery could speed up drug development
Knowledge-focused Not yet recruitingThis pilot study will test a new method to see how two pain medicines, naproxen and pregabalin, work in healthy adults. Up to 25 participants will receive each medicine and a placebo in random order. They will undergo several short, controlled pain tests, like a cold water hand b…
Sponsor: National Center for Complementary and Integrative Health (NCCIH) • Aim: Knowledge-focused
Last updated Sep 21, 2026 18:00 UTC
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Pain research seeks volunteers for future studies
Knowledge-focused Not yet recruitingThis study screens healthy volunteers and people with pain to see if they qualify for future pain research at the National Center for Complementary and Integrative Health. Screening includes medical history, physical exam, questionnaires, and optional sensory testing. No treatmen…
Sponsor: National Center for Complementary and Integrative Health (NCCIH) • Aim: Knowledge-focused
Last updated Sep 21, 2026 18:00 UTC
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Tiny needles probe rare gene disorder that blocks touch
Knowledge-focused Not yet recruitingThis study compares nerve function in people with PIEZO2 Deficiency Syndrome (a rare genetic condition that reduces touch and pain sensation) to healthy volunteers. Researchers use thin needles to record nerve activity while applying various sensations like brushing, heat, and pi…
Sponsor: National Center for Complementary and Integrative Health (NCCIH) • Aim: Knowledge-focused
Last updated Sep 21, 2026 18:00 UTC