HEALTHY VOLUNTEERS

This study is testing a new vaccine called VXB-241, designed to protect against two common viruses that cause serious lung infections: RSV and HMPV. It will involve 144 healthy adults, mostly aged 60-83, to check if the vaccine is safe and if it triggers a good immune response. R…

This study is testing a new vaccine designed to protect infants and toddlers from 21 strains of pneumococcal bacteria, which can cause serious infections like pneumonia and meningitis. It will compare the new vaccine's safety and ability to trigger an immune response to an alread…

This study is testing a new mRNA vaccine designed to protect against a specific type of bird flu (H5) that could cause a future pandemic. Researchers want to see if the vaccine is safe and if it triggers a good immune response in healthy adults. The study will test three differen…

This study is testing a new vaccine designed to protect against five major types of meningococcal disease (A, B, C, W, Y) in children. It involves 750 healthy infants, toddlers, and children up to 9 years old. The main goals are to see how well the new vaccine triggers a protecti…

This is the first human study of an experimental drug called KK4277 for lupus. Researchers are testing the safety and side effects of single and multiple doses in healthy volunteers and people with different types of lupus. The study will also measure how much of the drug gets in…

This early-stage study is testing different types of black raspberry candy to see which version best delivers the berry's healthy compounds to the body. Healthy volunteers try candies that release the berry's ingredients at different speeds to find the most effective formula. The…

This study aims to test a new digital inhaler device to see how safely and precisely it can deliver a harmless radioactive tracer to specific areas of the lungs. Healthy volunteers will use the inhaler once, and researchers will use special imaging to track where the tracer goes.…

This study collects and analyzes blood, DNA, and tissue samples from people with pulmonary fibrosis, their relatives, and healthy volunteers. Researchers are trying to understand what causes this serious lung-scarring disease by examining these biological materials. The study doe…

This is the first study to give the experimental drug ORKA-002 to people. Its main purpose is to check if it is safe and to see how the body processes it. The study will involve about 24 healthy volunteers who will receive a single injection. Researchers will carefully monitor pa…

This study aims to understand how a gentle, non-invasive electrical stimulation applied to the ear affects brain networks and the body's automatic nervous system. Researchers are testing this on 44 healthy volunteers to see how it changes brain wave patterns and heart rate variab…

This study is testing a new version of an eye scanner called Optical Coherence Tomography (OCT) on healthy adults. The goal is to see if the new scanner takes clearer, faster pictures than current models. Researchers will use the data from 20 healthy volunteers to fine-tune the t…

This is the first study testing the experimental drug JADE101 in humans. Researchers will give small, increasing doses to 32 healthy volunteers to check for side effects and see how the body processes the medication. The goal is to gather basic safety information to help plan fut…

This early study aims to check the safety and side effects of a new antibody drug called budoprutug in healthy people. About 38 volunteers will receive either the drug or a placebo as a single injection under the skin or into a vein. Researchers will monitor how the body handles …

This study is investigating whether a short course of an FDA-approved drug called sirolimus can improve blood flow to the brain and lungs. It involves healthy adults, some with a genetic risk for Alzheimer's disease, to see how their bodies respond. Researchers are using advanced…

This study aims to understand how gut bacteria influence how well a common cholesterol medication works, and how the medication itself changes gut bacteria. Researchers will give healthy volunteers either the cholesterol drug rosuvastatin or a placebo for 8 weeks and track change…

This research study aims to understand how analyzing people's genes (genome sequencing) can help us learn about heart disease and other health conditions. Researchers enrolled about 1,665 participants, including both healthy volunteers and people with heart disease, to collect bl…

This study aims to understand how a non-invasive brain stimulation technique called TMS affects decision-making, particularly in people with opioid use disorder. Researchers will compare 60 participants—some with opioid use disorder and some healthy volunteers—using brain scans a…

This study aims to see if two different injection devices deliver the same amount of an investigational drug, amlitelimab, into the body. It will involve 212 healthy adult volunteers who will receive a single injection. Researchers will measure drug levels in the blood, check for…

This is an early, small study to understand how the body absorbs and processes a new tablet drug called ABBV-722. It involves 11 healthy volunteers and tests whether taking the drug with or without food changes how much of it gets into the bloodstream. The main goal is to gather …

This early-stage study aims to understand how two gout medications, epaminurad and C2406, interact when taken together. It will involve 18 healthy adults to measure the levels of each drug in the body and check for safety. The goal is to gather basic information to guide future r…

This study aimed to understand how smoking and vaping cause DNA damage in mouth cells, which might lead to cancer. Researchers planned to compare damage levels in people who continued using these products, those who tried to quit, and non-users. The goal was to identify which typ…

This study aims to see if a new single pill containing three diabetes medicines works the same way in the body as taking the three medicines as separate pills. It involves healthy adult volunteers who will take both the single combination pill and the separate pills at different …

This study aims to gather basic information about how a special imaging agent, called [13C]pyruvate, behaves in the bodies of healthy volunteers during an MRI scan. Researchers want to see how this agent is distributed and used for energy in different organs to create a normal re…

This study was designed to understand how different drugs and drug combinations affect people's mood, pain tolerance, and mental performance. It planned to enroll healthy volunteers to take study drugs and complete tasks measuring their feelings, thinking, and pain response. The …

This study aims to understand what happens in the brain and body during a psychedelic experience. Researchers will give psilocybin (the active compound in 'magic mushrooms') to 12 healthy volunteers and scan their brains using MRI machines while they are under its effects. The go…

This study aims to understand the dream-like experiences people have while under light anesthesia. Healthy adult volunteers will receive two different types of sedation while researchers measure their brain waves and interview them about their experiences. The goal is to learn ho…

This early-stage study aims to understand how a new combination pill containing two cancer drugs is absorbed by the body compared to taking the drugs separately. It will also test whether eating food changes how the pill works. The study involves 24 healthy adult volunteers to ga…

This study is creating a large community health registry and sample bank in Cabarrus County and Kannapolis, North Carolina. It aims to enroll 50,000 local residents to provide their health information and biological samples. The collected data will be used as a resource for futur…