HEALTHY VOLUNTEERS

This early-stage study tested a new meningococcal B vaccine in 576 healthy people, from infants to adults. The goal was to check safety and how well the vaccine triggers an immune response, comparing it to existing vaccines. The trial was terminated early, so results may be limit…

This early-stage study tested a new drug called ASP5502 in healthy adults and people with Sjögren's syndrome, a condition where the immune system attacks moisture-producing glands. The main goal was to check safety and how well the drug is tolerated. Participants took single or m…

This study tested an experimental drug, PF-07258669, to help older adults (60-90 years) who are at risk of malnutrition or losing weight without trying. The goal was to see if the drug is safe and how it affects the body. The trial was stopped early after enrolling only 7 partici…

This study aimed to find substances in blood and urine that can detect kidney damage earlier than current methods. Researchers compared samples from healthy volunteers, people with low fluid levels, those at high risk for kidney failure, and patients with acute kidney failure. Th…

This early-phase study tested the safety and tolerability of a new drug called AMG 378 in 48 healthy adults aged 18 to 55. Participants received either single or multiple doses of the drug or a placebo, and researchers monitored side effects and how the drug moved through the bod…

This study tested new ways to take pictures of the lungs using MRI with special inhaled gases. Researchers wanted to see if these gases could create clearer images of how the lungs work. Healthy volunteers aged 6 to 75 took part. The study focused on improving the technology, not…

This study looked at whether a single session of non-invasive brain stimulation (alpha-tACS) could make people more flexible in their choices, especially those with a history of heavy drinking. Only 7 healthy adults and risky drinkers took part before the study was stopped. Resea…

This early-stage study tested an experimental drug called iCP-NI in 24 healthy adults to see if it is safe and how the body processes it. Participants received either the drug or a placebo through an IV. The study was stopped early, and it does not aim to treat any disease.

This study used anonymous online surveys to understand why teens vape, how they feel, and what parents know. About 726 teens (ages 13-18) and their parents answered questions on vaping habits, mood, and social pressures. No treatments or medications were tested; the goal was simp…

This study looked at whether a mindfulness training program could change brain connections in teenagers who vape tobacco. Researchers used brain scans to see if these changes were linked to less vaping. The study was stopped early and included only 14 participants, so results are…

This study tested two new liquid versions of the drug maribavir to see how well they are absorbed and how they taste compared to the current tablet. It involved 20 healthy adults aged 18-50. The study was terminated early, so results are limited.

This study looked at how healthy adults react to breathing air with less oxygen for several days. Researchers measured oxygen levels in the blood, red blood cell production, and lung pressure to understand the body's response. The goal was to learn about safety and basic body cha…

This early-stage study tested a new radioactive drug called [11C]MC1 to see if it could help PET scans show inflammation in the body. Researchers studied healthy volunteers and people with rheumatoid arthritis or inflammatory muscle disease. The study was stopped early, but the g…