GLAUCOMA

This study is testing whether a tiny, slow-release implant placed in the eye during cataract surgery works as well as daily prescription eye drops to control eye pressure in people with mild to moderate glaucoma. The implant is designed to release medication continuously over tim…

This early-stage study is testing whether applying insulin directly to the eye as a drop is safe for people with glaucoma and other optic nerve conditions. Researchers will enroll 52 participants to use the drops for 1-2 months while closely monitoring for any side effects. The s…

This study is testing if a long-acting eye implant (Durysta) can help control glaucoma while reducing the need for daily eye drops. Researchers want to see if using fewer drops leads to less inflammation and irritation on the eye's surface. The study will measure inflammation mar…

This study is testing a modified eye surgery for people with glaucoma. It is for patients who had a combined cataract and glaucoma procedure that failed to control their eye pressure soon after. The goal is to see if this new surgical approach can better manage the disease and lo…

This study follows glaucoma patients for 8 to 14 years after they received a tiny implant called Hydrus to help lower pressure inside their eye. Researchers want to see how well the implant continues to work over many years and whether patients still need additional medications o…

This study aims to understand how the eye heals after minimally invasive glaucoma surgery. Researchers will use special imaging to track 300 patients who undergo procedures to open blocked drainage angles in the eye. The goal is to gather information that helps standardize and im…

This study is testing whether using pilocarpine eye drops after a combined glaucoma and cataract surgery helps control eye pressure better than surgery alone. It involves 142 patients with glaucoma who are having this specific two-in-one procedure. The goal is to see if the drops…

This study is testing whether a weekly, 30-minute electrical stimulation treatment for the eye can help slow the progression of vision loss in people with open-angle glaucoma. Fifty participants will be randomly assigned to receive either the real stimulation or a sham (fake) tre…

This study is testing if a tiny, slow-release implant placed in the eye during cataract surgery works as well as daily eye drops to lower eye pressure in people with mild to moderate glaucoma. About 400 people who need cataract surgery and have glaucoma will be randomly assigned …

This study is testing whether a nutritional supplement called BrudyGlauco, containing DHA and citicoline, can help protect vision in people with glaucoma. Glaucoma damages the optic nerve and can lead to vision loss. Researchers want to see if taking this supplement for a year, a…

This study is testing a small, dissolvable implant placed inside the eye to slowly release medication for glaucoma. It aims to control eye pressure more conveniently than daily eye drops. The trial will compare the implant's safety and effectiveness against standard eye drop trea…

This study is testing whether a gentle, painless electrical current applied near the eye can help preserve vision in people with glaucoma. Researchers will compare the real treatment to a fake (sham) treatment in 30 participants to see if it slows vision loss. The goal is to find…

This study is testing whether a gentle, non-invasive brain stimulation technique can help improve vision in people with glaucoma. Researchers will use repetitive transcranial alternating current stimulation (rtACS) to try to activate damaged eye nerve cells. They will measure cha…

This study is testing whether adding a tiny device called an iStent during cataract surgery helps lower eye pressure in people who also have glaucoma. Researchers will compare patients who get the stent with their cataract surgery to those who get cataract surgery alone. The goal…

This study is testing if a common diabetes medication, metformin, can protect the optic nerve and slow vision loss in people with glaucoma. It will involve 125 glaucoma patients whose vision is getting worse despite standard treatment. Participants will take either metformin or a…

This study is testing a new eye drop called BL1107 to see if it is safe and effective for controlling eye pressure in adults with glaucoma or ocular hypertension. Researchers will compare two strengths of BL1107 against a standard eye drop (timolol) over 28 days. The main goal is…

This study is testing a small, long-lasting implant placed inside the eye to lower eye pressure for people with glaucoma. It aims to see if this single implant works as well as or better than using prescription eye drops twice a day. The goal is to provide a new, convenient optio…

This study is testing whether a new artificial intelligence (AI) tool can help doctors screen for glaucoma more accurately and efficiently. It will involve 1040 adults with diabetes in Singapore. Participants will be randomly assigned to have their eye photos analyzed either by t…

This study is testing whether a telemedicine approach can detect serious eye diseases as effectively as traditional in-person eye exams. Researchers will compare detection rates for glaucoma, diabetic retinopathy, and cataracts in 900 patients at community health centers. The goa…

This study is testing four new designs for the tip of an eye pressure test device. The goal is to find a tip that is comfortable enough to use without needing numbing eye drops. Researchers will compare the new tips to the standard one that requires drops. The most comfortable de…

This study aims to test an artificial intelligence (AI) eye screening program in community health centers that serve low-income and uninsured patients. It will screen 1,800 adults at risk for glaucoma, diabetic retinopathy, cataracts, or vision problems to see if the program effe…

This study is testing new portable devices that aim to measure eye pressure more accurately and consistently than current methods. Researchers will compare two experimental devices against the standard eye pressure tests used in clinics today. The goal is to develop better tools …

This study is testing a new, easier-to-use version of a handheld eye scanner. The goal is to see if its automatic alignment feature can take clear pictures of the back of the eye (retina) in both adults and children. Researchers will enroll 50 volunteers and patients to see how w…

This study aims to compare two types of handheld eye scanners to see which works better for imaging children's retinas. Researchers will test both a contact scanner and a non-contact scanner on 20 pediatric patients and 10 healthy adults. The goal is to determine which system pro…

This study is testing whether a community and faith-based support program can help more Black Americans at high risk for glaucoma get to eye doctor appointments. Researchers want to see if providing extra resources and education makes people more likely to get the preventive care…

This study is testing whether a gentle exercise called Baduanjin can help people with glaucoma. Researchers will enroll 60 older adults with high eye pressure and split them into two groups. One group will do the exercise for 60 minutes daily for eight weeks, while the other grou…

This study is testing whether Xiidra eye drops can help relieve dry, uncomfortable eyes in people with glaucoma who use multiple eye medications. Researchers will measure changes in eye dryness, surface damage, and quality of life over 12 weeks. The study is recruiting 75 glaucom…

This study is testing whether listening to music helps children and teenagers with glaucoma pay better attention during important eye exams called visual field tests. Researchers at Johns Hopkins University are enrolling 40 young patients, ages 8 to 17, to see if music makes the …

This study is testing whether adding brimonidine eye drops can reduce eye redness in people already using a specific glaucoma medication combination. Researchers will enroll 35 adults with open-angle glaucoma who experience moderate redness from their current treatment. The goal …

This study is testing whether a special eye training program can help people with glaucoma use their remaining vision more effectively. 70 participants will be randomly assigned to either receive the training or be in a control group. The training uses visual and audio feedback t…

This study aims to understand how measuring pressure and fluid flow inside the eye during surgery might help doctors predict a patient's recovery. Researchers will observe 150 adults having cataract or glaucoma surgery, using a special sensor to take measurements during the opera…

This study aims to understand how glaucoma, an eye disease, might affect more than just vision—specifically sleep, mood, alertness, and thinking skills. Researchers will compare 120 adults with glaucoma to healthy adults of similar age. They will test if damage to special light-s…

This study aims to find better ways to measure how quickly glaucoma worsens over time. Researchers will follow 200 glaucoma patients for three years, comparing two different eye tests and a special scan of the retina. The goal is to understand which method gives doctors the clear…

This study aims to understand if damage to a protective lining inside tiny blood vessels is linked to glaucoma, a common eye disease that can lead to vision loss. Researchers will compare 100 people with glaucoma to people without it, using a special camera to take pictures of th…

This study aims to collect detailed scan images of the eye from 180 people. It includes participants with various eye conditions like macular degeneration, glaucoma, and corneal diseases, as well as people with healthy eyes. The goal is to build a large database of images to help…

This study is testing a new, non-contact imaging technique called Brillouin microscopy to measure the stiffness of the cornea in people with glaucoma. Researchers want to see if cornea stiffness differs between people with different types of glaucoma and healthy individuals, and …

This study aims to understand if changes in blood flow regulation in the eye can serve as an early warning sign for glaucoma. Researchers will compare 90 participants—some with early glaucoma, some at risk, and some healthy controls—using advanced imaging to measure blood flow in…

This study aims to test new, high-tech eye imaging systems that can see microscopic details of the eye, like individual cells and blood flow, which are not visible with standard equipment. Researchers will enroll 1,200 participants, including people with various eye conditions an…