Eye blood flow may reveal glaucoma before vision loss
NCT ID NCT05344274
First seen Jan 10, 2026 · Last updated Jun 23, 2026 · Updated 28 times
Summary
This study is testing whether measuring blood flow in the retina can help spot early glaucoma, a leading cause of blindness. Researchers will use special dyes and oxygen tests to see how eye blood vessels respond in 90 adults with early glaucoma. The goal is to create a reliable biomarker for earlier diagnosis and better treatment timing.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Food and Drug Administration (FDA)
RECRUITINGSilver Spring, Maryland, 20903, United States
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University of Maryland Faculty Physicians, Inc
RECRUITINGBaltimore, Maryland, 21201, United States
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University of Maryland Medical Center
RECRUITINGBaltimore, Maryland, 21201, United States
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University of Maryland, Baltimore
RECRUITINGBaltimore, Maryland, 21201, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Indocyanine green dye and oxygen
What this could lead to
If successful, this could lead to a simple, non-invasive test to detect glaucoma earlier, potentially preventing vision loss.
What could go wrong
This is a small, early-phase study focused on finding a biomarker, not a treatment. The results may not translate into a widely usable test.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.