Glaucoma

This study tests whether removing the ripcord from a glaucoma drainage device more than 3 months after placement lowers eye pressure. Adults with glaucoma who have had the ripcord in place for over 3 months will have it removed during a routine clinic visit. Researchers will meas…

This trial tests a new device called VividFlo, a small implant placed under the eye's surface to help drain fluid and lower pressure in people with glaucoma. The study involves 10 adults with glaucoma in one eye, who will receive the implant during surgery. Researchers will track…

This trial compares two surgical implants—the Baerveldt Glaucoma Implant and the Paul Glaucoma Implant—in people with glaucoma that is not well controlled by eye drops. Both devices are tiny tubes placed in the eye to drain fluid and lower pressure. The study will track which imp…

This trial investigates whether a 12-week home-based circuit training program can reduce intraocular pressure and improve retinal health in people with glaucoma. Participants are randomly assigned to either the exercise program plus standard care or standard care alone. The study…

This study aims to find the best material to cover a small drainage device used in glaucoma surgery. Glaucoma is a leading cause of blindness due to high pressure in the eye. The researchers will compare three different patch materials (donor sclera, cornea, and pericardium) in 1…

This early study tests a small ring placed in the eye that slowly releases the drug bimatoprost to lower eye pressure in people with glaucoma or ocular hypertension. The ring is implanted during a quick surgery and may work for up to 3 years. The trial includes 24 adults and comp…

This study tests whether placing a temporary stitch inside a tiny drainage device (Preserflo) can reduce the risk of dangerously low eye pressure after glaucoma surgery. The device is already used in France to lower eye pressure, but low pressure can still happen. About 192 adult…

This study tests whether a structured glaucoma awareness program helps patients in Nepal follow their treatment better. Glaucoma requires lifelong care to prevent blindness, but many patients struggle with adherence. Researchers will measure changes in adherence using a questionn…

This study tests whether a laser treatment called DSLT can lower eye pressure and reduce the number of eye drops needed in Asian patients with normal tension glaucoma. About 40 adults will receive the laser and be followed for 12 months. The goal is to see if the laser can help c…

This study looks at how Rocklatan eye drops change blood flow in the eyes of 30 people with early-stage glaucoma. Researchers will use special imaging to measure blood flow before and after using the drops for up to a year. The goal is to better understand the drug's effects on e…

This trial tests whether the Tomey FT-1000, a non-contact tonometer that measures eye pressure with a puff of air, agrees with the standard Goldmann applanation tonometer, which touches the eye. Researchers will enroll 30 adults with glaucoma and measure eye pressure with both de…

This study tests an artificial intelligence (AI) system called GlaukomAI that analyzes standard eye photos to detect glaucoma, a leading cause of blindness. Researchers will enroll 1,200 participants to see how accurately the AI identifies glaucoma compared to expert doctors. If …

This study will develop and test an artificial intelligence system to detect common eye diseases like glaucoma, cataracts, and diabetic retinopathy using 15,000 existing eye images from Costa Rican patients. The goal is to create a tool that works accurately for local populations…

This study will test a new artificial intelligence (AI) system that reads eye scans (OCT) to diagnose common blinding eye diseases like diabetic retinopathy, glaucoma, and age-related macular degeneration. Researchers will collect 2000 eye scans from patients at Peking Union Medi…

This study tests whether a structured referral tracking program helps adults in Pakistan complete follow-up eye care after community screenings. 500 participants will receive either standard referral or extra support like counseling and weekly reminders. The goal is to prevent bl…

This study tests whether an online meditation program can reduce stress and improve quality of life in people with glaucoma. Participants aged 65 and older will be randomly assigned to either meditation plus usual care or usual care alone. They will fill out questionnaires about …

This study tests a device called Nanodropper that attaches to eye drop bottles and makes each drop smaller. Many glaucoma patients have trouble getting drops into their eyes or use too much, wasting medication. The trial will see if the device helps patients finish their bottles …

This study tests a smart cap called iD2 that fits on eye drop bottles. It tracks when you remove the cap and sends reminders to your phone if you forget a dose. The goal is to help people with glaucoma take their drops more regularly, which can prevent vision loss. About 100 adul…

This study tests whether a structured blinking exercise can improve dry eye symptoms in adults with glaucoma who use eye drops. 45 participants will perform 15 close-squeeze-open blinks three times daily for two weeks. Researchers will measure symptom changes and tear film stabil…

This study tests whether Meta AI glasses, connected to the Be My Eyes network, can help people with permanent vision loss walk and move around more easily. The glasses describe scenes and objects in real time. Fifty participants will use the glasses and report changes in their qu…

This study tests whether Lumify, a low-dose brimonidine eye drop already approved for redness, can safely reduce eye redness and eyelid droop in 60 glaucoma patients who already use stronger brimonidine drops. Researchers will measure redness, eye pressure, and eyelid position af…

Researchers at Shanghai General Hospital are studying whether exercise relates to visual function in people with glaucoma. About 100 patients aged 18 to 100 answer a questionnaire about their physical activity. The team then measures central visual field, retinal nerve fiber laye…

This study will screen over 7,000 adults aged 40+ living in affordable housing in New York City for undiagnosed high blood pressure and glaucoma. Participants who need follow-up care will be randomly assigned to receive text message reminders or usual care. The goal is to see if …

This study is testing whether a specialized eye scanner called the MONA IV can capture clear, detailed images of the retina's tiny cells and blood vessels. Researchers will use it in people with conditions like glaucoma or age-related macular degeneration, as well as in healthy v…

This study looks at whether a common type of glaucoma eye drop (prostaglandin analogues) can protect the eye's nerve cells directly, not just by lowering eye pressure. Researchers will review medical records from 1500 adults with glaucoma over 3 years, comparing those on prostagl…