BREAST NEOPLASMS

This study tested whether adding the drug palbociclib to standard hormone therapy (letrozole) helps slow the growth of advanced breast cancer in Asian women who have gone through menopause. About 340 women with a specific type of breast cancer (ER-positive, HER2-negative) that ha…

This early-stage study tested a new drug called H3B-6545 in 33 Japanese women with a common type of breast cancer (ER-positive, HER2-negative). The main goal was to see if the drug is safe and tolerable, and to find the right dose for Japanese patients. Participants had already t…

This study tested a drug called leflunomide, usually used for arthritis, in 17 women with metastatic triple negative breast cancer. The goal was to see if it is safe and can help control the cancer. The drug is taken daily by mouth and works by blocking a protein that cancer cell…

This study tested several immunotherapy-based drug combinations in 144 people with advanced hormone-receptor-positive, HER2-negative breast cancer that had gotten worse after standard treatment with a CDK4/6 inhibitor. Participants were randomly assigned to receive either a stand…

This study looked at 140 women with early-stage, low-risk breast cancer to compare two radiation approaches after breast-conserving surgery. One group received radiation to the whole breast, while the other received a shorter course targeting only the tumor area. The goal was to …

This study looked at how well anti-HER2 drugs work in Egyptian women with HER2-positive breast cancer, an aggressive type. Researchers followed 80 patients to see if single or combination therapy improved survival and safety. The goal was to understand real-world effectiveness in…

This study tested whether an AI program called Carebot AI MMG can spot breast cancer on mammograms as well as human radiologists. Researchers looked at 222 mammograms from women who had breast cancer screening. The AI's results were compared to readings from three experienced rad…

This study tested whether a fast (abbreviated) breast MRI can detect cancers that mammography misses in women who had breast-conserving therapy for breast cancer at least three years earlier. 184 women with a recent negative mammogram and no symptoms were enrolled. The goal was t…

This study tested whether an AI program called CadAI-B Dx helps doctors spot breast cancer on ultrasound images. Researchers looked at 797 cases (350 with cancer, 447 benign) and had 16 doctors read the images with and without the AI. The goal was to see if the AI improves accura…

This study looked at whether angiomammography (a type of contrast-enhanced mammogram) can predict if breast cancer will completely disappear after chemotherapy, compared to MRI. Researchers followed 67 women with breast cancer who received chemotherapy before surgery. The goal wa…

This study tested whether a smartphone app could help breast cancer patients on oral chemotherapy report side effects and stay in touch with their healthcare team. 28 women with metastatic breast cancer taking pills like palbociclib or capecitabine used the app to track their sym…

This study tested a remote monitoring system called CONTINUUM+ CONNECT in 411 adults with metastatic breast, lung, colorectal, or prostate cancer. Participants used the system (with or without home nursing) or received standard care. The goal was to see if the system improved phy…

This study tested whether a home-based exercise program could improve physical fitness, reduce fatigue, and enhance quality of life for 36 breast cancer patients in Indonesia. Participants did supervised aerobic and resistance training at home for 12 weeks. The goal was to see if…

This study tested a program to help breast cancer patients manage joint and muscle pain caused by hormone therapy. 289 patients received either the program or standard care. The program included health education and nursing guidance tailored to the patient's cultural background. …

This study tested whether injecting a local anesthetic (ropivacaine) during breast cancer surgery could prevent chronic pain that sometimes lingers for months. Researchers compared pain levels three months after surgery in 260 women who either received the injection or a placebo.…

This study looked at 80 women having major breast cancer surgery to compare two pain relief methods: a nerve block (ESPB) and an IV lidocaine drip. The goal was to see which approach leads to a better recovery and less pain after surgery. Results will help doctors choose the best…

This study looked at whether starting a tailored exercise program before breast cancer treatment helps prevent heart damage and other side effects better than exercising only during treatment. 100 women with early-stage breast cancer participated. The goal is to improve quality o…

This study looked at why some women have dense breasts on mammograms and why that increases breast cancer risk. Researchers collected medical records, biopsy tissue, and health updates from 466 women aged 40-65 over 10 years. The goal was to understand what cells make up dense ar…

This study tested whether a special 3D ultrasound technique (called shear wave elastography) can accurately predict how well breast tumors respond to chemotherapy before surgery. Researchers measured tumor stiffness in 140 women with locally advanced breast cancer at several poin…

This study examined 52 breast cancer tumor samples and some blood samples to find chemical markers (metabolites) that might help understand different types of breast cancer better. The goal was to learn more about how cancer cells use energy and to find possible targets for futur…

This study looked at 77 women with breast lesions that only show up on special contrast-enhanced mammograms. Doctors wanted to find out the smallest number of tissue samples needed to make a reliable diagnosis. The goal is to make the biopsy process more efficient and comfortable…

This study looked at how breast cancer treatments affect sexual health in women. Researchers followed 25 women who had non-metastatic breast cancer and were referred for fertility preservation. Participants filled out anonymous questionnaires about their sexual function, quality …

This study involved 775 women who had breast-conserving surgery and radiation for breast cancer. Researchers looked at how different combinations of surgery and radiation techniques affected breast firmness (fibrosis) and cosmetic results. The goal was to find ways to improve bot…

This study looked at how common BRCA1 and BRCA2 gene mutations are in Hispanic/Latino women with breast cancer. About 266 women gave saliva samples and answered questions about their health and family history. No treatment was given—the goal was simply to gather information to he…

This study looked back at medical records of over 500 women in Gulf countries whose breast cancer had spread and was previously labeled as HER2-negative. Researchers re-checked the original tumor samples to find out how many actually had a newer subtype called HER2-low. The goal …

This study looked at how doctors in Poland treat a common type of advanced breast cancer (HR+ HER2-). Researchers collected information from 440 patients to understand which treatments are used and how they change over time. The goal was to learn more about real-world care, not t…

This study involved 50 women who finished treatment for early-stage breast cancer. Researchers wanted to see if a special 'remission' consultation could improve their quality of life over the next year. Participants filled out questionnaires about their well-being and body image …

This study looked at 729 breast cancer patients who had surgery followed by radiation. Researchers checked their thyroid function before and after radiation to see how many developed hypothyroidism (an underactive thyroid). They also studied which radiation doses and techniques r…

This completed study looked at 684 people with breast cancer to see if those with unstable living conditions (social fragility) are more likely to be diagnosed at a later, harder-to-treat stage. Researchers compared early-stage (good prognosis) and late-stage (poor prognosis) cas…