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Digestive system disorder
MONDO:0004335A disease or disorder that involves the digestive system.
Also known as: digestive disease, digestive system disease, digestive system disease or disorder, digestive system disorder, disease of digestive system, disease or disorder of digestive system, disorder of digestive system, gastroenterological system disease
16300 clinical trials for this condition and its sub-types, 168 tagged with Digestive system disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Digestive system disorder
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Digestive system cancer 267 trials · 7,054 incl. sub-types
15 sub-types
- Digestive system carcinoma 25 trials · 4,876 incl. sub-types Sub-types →
- Intestinal cancer 25 trials · 2,786 incl. sub-types Sub-types →
- Liver cancer 254 trials · 1,700 incl. sub-types Sub-types →
- Malignant pancreatic neoplasm 899 trials · 1,444 incl. sub-types Sub-types →
- Gastric cancer 724 trials · 1,034 incl. sub-types Sub-types →
- Esophageal cancer 408 trials · 787 incl. sub-types Sub-types →
- Pharynx cancer 10 trials · 495 incl. sub-types Sub-types →
- Oral cavity cancer 42 trials · 288 incl. sub-types Sub-types →
- Gastroesophageal cancer 157 trials
- Gallbladder cancer 73 trials · 106 incl. sub-types Sub-types →
- Gastrointestinal lymphoma 0 trials · 7 incl. sub-types Sub-types →
- Jaw cancer 1 trial · 5 incl. sub-types Sub-types →
- Digestive system melanoma 0 trials · 2 incl. sub-types Sub-types →
- Malignant tumor of floor of mouth 0 trials · 2 incl. sub-types Sub-types →
- Spleen cancer 0 trials · 2 incl. sub-types Sub-types →
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Pancreas disorder 44 trials · 5,580 incl. sub-types
14 sub-types
- Endocrine pancreas disorder 1 trial · 3,923 incl. sub-types Sub-types →
- Pancreatic neoplasm 926 trials · 1,573 incl. sub-types Sub-types →
- Pancreatitis 120 trials · 203 incl. sub-types Sub-types →
- Exocrine pancreatic insufficiency 29 trials Sub-types →
- Recurrent acute pancreatitis 19 trials
- Accessory pancreas 0 trials
- Acinar cystic transformation of the pancreas 0 trials
- Annular pancreas 0 trials
- Congenital pancreatic cyst 0 trials
- Follicular cholangitis and pancreatitis 0 trials
- Lymphoepithelial cyst of the pancreas 0 trials
- Pancreatic mucinous ductal ectasia 0 trials
- Pancreatic steatorrhea 0 trials
- Pancreatic triacylglycerol lipase deficiency 0 trials Sub-types →
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Intestinal disorder 70 trials · 5,432 incl. sub-types
58 sub-types
- Large intestine disorder 2 trials · 3,811 incl. sub-types Sub-types →
- Intestinal neoplasm 4 trials · 3,074 incl. sub-types Sub-types →
- Inflammatory bowel disease 429 trials · 1,079 incl. sub-types Sub-types →
- Gastroenteritis 20 trials · 837 incl. sub-types Sub-types →
- Small intestine disorder 7 trials · 385 incl. sub-types Sub-types →
- Irritable bowel syndrome 221 trials
- Bowel dysfunction 11 trials · 210 incl. sub-types Sub-types →
- Glucose-galactose malabsorption 2 trials · 151 incl. sub-types Sub-types →
- Malabsorption syndrome 13 trials · 118 incl. sub-types Sub-types →
- Intestinal obstruction 44 trials · 91 incl. sub-types Sub-types →
- Eosinophilic gastrointestinal disease 9 trials · 73 incl. sub-types Sub-types →
- Intestinal fistula 6 trials · 63 incl. sub-types Sub-types →
- Necrotizing enterocolitis 51 trials Sub-types →
- Intestinal motility disease 10 trials · 39 incl. sub-types Sub-types →
- Short bowel syndrome 39 trials Sub-types →
- Diverticulitis 28 trials · 34 incl. sub-types Sub-types →
- Chronic intestinal failure 24 trials
- Neurogenic bowel 22 trials
- Postgastrectomy syndrome 2 trials · 20 incl. sub-types Sub-types →
- Hypertrophic pyloric stenosis 16 trials Sub-types →
- Parasitic intestinal disorder 0 trials · 16 incl. sub-types Sub-types →
- Ischemic bowel disorder 8 trials · 15 incl. sub-types Sub-types →
- Endometriosis of intestine 9 trials
- Intestinal perforation 9 trials Sub-types →
- Intestinal polyp 8 trials
- Protein-losing enteropathy 7 trials
- Intestinal atresia 3 trials · 6 incl. sub-types Sub-types →
- Chronic intestinal vascular insufficiency 4 trials
- Refractory celiac disease 4 trials
- Volvulus of midgut 4 trials Sub-types →
- Abetalipoproteinemia 2 trials
- Pneumatosis cystoides intestinalis 2 trials
- Angiodysplasia of intestine 1 trial
- Chronic enteropathy associated with SLCO2A1 gene 1 trial
- Cryptogenic multifocal ulcerous stenosing enteritis 1 trial
- Steatorrhea 1 trial Sub-types →
- 4-hydroxyphenylacetic aciduria 0 trials
- Aeromonas hydrophila intestinal disease 0 trials
- NK-cell enteropathy 0 trials
- Satoyoshi syndrome 0 trials
- Whipple disease 0 trials
- Aplasia cutis congenita-intestinal lymphangiectasia syndrome 0 trials
- Chronic atrial and intestinal dysrhythmia 0 trials
- Chronic diarrhea with villous atrophy 0 trials
- Collagenous sprue 0 trials
- Congenital diarrhea 7 with exudative enteropathy 0 trials
- Congenital enterocyte heparan sulfate deficiency 0 trials
- Cytosolic phospholipase-A2 alpha deficiency associated bleeding disorder 0 trials
- Intestinal dysmotility syndrome 0 trials
- Intestinal lymphangiectasia 0 trials Sub-types →
- Intractable diarrhea-choanal atresia-eye anomalies syndrome 0 trials
- Isolated mesenteric vein thrombosis 0 trials
- Malakoplakia 0 trials
- Mucocele of appendix 0 trials
- Primary desmosis coli 0 trials
- Solitary rectal ulcer syndrome 0 trials
- Trichohepatoenteric syndrome 0 trials Sub-types →
- Visceral leiomyopathy, African degenerative 0 trials
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Hepatobiliary disorder 10 trials · 3,893 incl. sub-types
4 sub-types
- Liver disorder 323 trials · 3,604 incl. sub-types Sub-types →
- Hepatobiliary neoplasm 26 trials · 1,772 incl. sub-types Sub-types →
- Biliary tract disorder 22 trials · 1,001 incl. sub-types Sub-types →
- Gallbladder disorder 26 trials · 219 incl. sub-types Sub-types →
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Stomach disorder 4 trials · 1,623 incl. sub-types
19 sub-types
- Gastric neoplasm 685 trials · 1,101 incl. sub-types Sub-types →
- Gastroesophageal reflux disease 217 trials Sub-types →
- Functional gastric disease 47 trials · 213 incl. sub-types Sub-types →
- Gastritis 21 trials · 50 incl. sub-types Sub-types →
- Hiatus hernia 49 trials Sub-types →
- Pyloric stenosis 15 trials · 31 incl. sub-types Sub-types →
- Gastric intestinal metaplasia 18 trials
- Gastric ulcer 13 trials Sub-types →
- Stomach polyp 4 trials · 6 incl. sub-types Sub-types →
- Gastric dilatation 3 trials
- Achlorhydria 1 trial
- Pylorospasm 1 trial
- Dieulafoy lesion 0 trials
- Angiodysplasia of stomach 0 trials
- Cascade stomach 0 trials
- Gastric duplication 0 trials
- Non-hypoproteinemic hypertrophic gastropathy 0 trials
- Pyloric duplication 0 trials
- Stomach diverticulosis 0 trials
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Upper digestive tract disorder 6 trials · 1,226 incl. sub-types
2 sub-types
- Esophageal disorder 20 trials · 1,221 incl. sub-types Sub-types →
- Internal hirudiniasis 0 trials
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Autoimmune disorder of gastrointestinal tract 0 trials · 936 incl. sub-types
7 sub-types
- Type 1 diabetes mellitus 815 trials · 816 incl. sub-types Sub-types →
- Celiac disease 79 trials Sub-types →
- Autoimmune hepatitis 30 trials · 31 incl. sub-types Sub-types →
- Autoimmune enteropathy 2 trials · 11 incl. sub-types Sub-types →
- Autoimmune gastritis 3 trials
- Autoimmune pancreatitis 3 trials Sub-types →
- IgG4-related sclerosing cholangitis 0 trials
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Digestive system infectious disorder 4 trials · 605 incl. sub-types
22 sub-types
- Viral hepatitis 12 trials · 443 incl. sub-types Sub-types →
- Infectious colitis 0 trials · 69 incl. sub-types Sub-types →
- Intestinal infectious disease 3 trials · 49 incl. sub-types Sub-types →
- Small intestinal bacterial overgrowth 18 trials
- Parasitic intestinal disorder 0 trials · 16 incl. sub-types Sub-types →
- Liver abscess (disease) 4 trials
- Campylobacteriosis 3 trials Sub-types →
- Bacterial gastritis 2 trials
- Gastrointestinal tuberculosis 0 trials · 2 incl. sub-types Sub-types →
- Aeromonas hydrophila intestinal disease 0 trials
- Salmonella gastroenteritis 0 trials
- Whipple disease 0 trials
- Anal verrucous carcinoma 0 trials
- Bacterial esophagitis 0 trials
- Colorectal Kaposi sarcoma 0 trials Sub-types →
- Fungal esophagitis 0 trials Sub-types →
- Fungal gastritis 0 trials
- Internal hirudiniasis 0 trials
- Oropharyngeal anthrax 0 trials
- Polycystic echinococcosis 0 trials
- Viral esophagitis 0 trials
- Viral gastritis 0 trials Sub-types →
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Neoplasm of oropharynx 3 trials · 279 incl. sub-types
2 sub-types
- Oropharynx cancer 149 trials · 279 incl. sub-types Sub-types →
- Benign neoplasm of oropharynx 0 trials
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Digestive system neuroendocrine neoplasm 52 trials · 167 incl. sub-types
7 sub-types
- Digestive system neuroendocrine tumor, grade 1/2 66 trials · 145 incl. sub-types Sub-types →
- Pancreatic neuroendocrine neoplasm 9 trials · 85 incl. sub-types Sub-types →
- Intestinal neuroendocrine neoplasm 7 trials · 21 incl. sub-types Sub-types →
- Gastric neuroendocrine neoplasm 3 trials · 6 incl. sub-types Sub-types →
- Liver neuroendocrine carcinoma 3 trials Sub-types →
- Gallbladder neuroendocrine neoplasm 0 trials Sub-types →
- Salivary gland small cell carcinoma 0 trials
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Diarrheal disease 80 trials · 117 incl. sub-types
7 sub-types
- Acute diarrhea 10 trials · 42 incl. sub-types Sub-types →
- Inflammatory diarrhea 0 trials · 33 incl. sub-types Sub-types →
- Chronic diarrheal disease 10 trials Sub-types →
- Congenital diarrhea 0 trials · 5 incl. sub-types Sub-types →
- Secretory diarrhea 0 trials · 5 incl. sub-types Sub-types →
- Diarrheal disease secondary to altered bowel motility 0 trials Sub-types →
- Non-infectious diarrheal disease 0 trials Sub-types →
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Peptic ulcer disease 26 trials · 67 incl. sub-types
6 sub-types
- Peptic esophagitis 24 trials
- Gastric ulcer 13 trials Sub-types →
- Duodenal ulcer 7 trials
- Gastrojejunal ulcer 6 trials
- Active peptic ulcer disease 3 trials
- Peptic ulcer perforation 3 trials
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Gastrointestinal mucositis 3 trials · 52 incl. sub-types
2 sub-types
- Intestinal infectious disease 3 trials · 49 incl. sub-types Sub-types →
- Inflammatory diarrhea 0 trials · 33 incl. sub-types Sub-types →
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Benign digestive system neoplasm 0 trials · 41 incl. sub-types
10 sub-types
- Pleomorphic adenoma 12 trials
- Hepatobiliary benign neoplasm 2 trials · 8 incl. sub-types Sub-types →
- Benign neoplasm of pancreas 7 trials Sub-types →
- Intestinal benign neoplasm 1 trial · 7 incl. sub-types Sub-types →
- Benign neoplasm of esophagus 3 trials Sub-types →
- Benign neoplasm of stomach 1 trial · 2 incl. sub-types Sub-types →
- Hepatocellular adenoma 2 trials Sub-types →
- Benign neoplasm of gallbladder 0 trials Sub-types →
- Benign neoplasm of oropharynx 0 trials
- Bile duct papillary neoplasm 0 trials Sub-types →
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Hereditary mixed polyposis syndrome 5 trials · 6 incl. sub-types
2 sub-types
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Juvenile polyposis syndrome 5 trials
3 sub-types
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Gastrointestinal polyp 0 trials · 3 incl. sub-types
2 sub-types
- Gastrointestinal hamartoma 0 trials · 3 incl. sub-types Sub-types →
- Anal polyp 0 trials Sub-types →
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Cronkhite-Canada syndrome 1 trial
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Hyperplastic polyposis syndrome 1 trial
2 sub-types
- Colon serrated polyposis 1 trial
- Sessile serrated polyposis cancer syndrome 0 trials
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Meckel diverticulum 0 trials
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Caudal duplication 0 trials
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Common mesentery 0 trials
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Congenital peritoneal encapsulation 0 trials
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Digestive duplication 0 trials
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Diverticulosis, small-intestinal 0 trials
Most studied deeper sub-types
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New drug shows promise for rare stomach disorder in japanese study
Disease control CompletedThis study tested a drug called CC-93538 (Cendakimab) in 48 Japanese adults and adolescents with eosinophilic gastroenteritis, a condition where certain white blood cells build up in the digestive tract causing pain and other symptoms. The trial was randomized and placebo-control…
Phase 3 • Sponsor: Celgene • Aim: Disease control
Last updated Sep 16, 2026 00:00 UTC
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Can a single pill tackle both fatty liver and diabetes?
Disease control CompletedThis phase 2 trial is testing whether an experimental drug called HTD1801 can reduce liver fat and improve blood sugar control in adults who have both nonalcoholic steatohepatitis (NASH) and type 2 diabetes. Participants receive either HTD1801 or a placebo for 18 weeks, and resea…
Phase 2 • Sponsor: HighTide Therapeutics (Hong Kong) Limited • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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Can a glass of pomegranate juice tame gut inflammation?
Disease control CompletedThis trial investigates whether drinking pomegranate juice for 12 weeks can reduce gut inflammation in people with Crohn's disease or ulcerative colitis who are in remission. Participants will drink either pomegranate juice or a placebo beverage twice daily, and researchers will …
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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Drain or no drain? landmark trial settles debate after rectal cancer surgery
Disease control CompletedThis study tested whether placing a temporary drain in the pelvis after rectal cancer surgery reduces the risk of serious infections like leaks or abscesses. About 500 patients were randomly assigned to receive a drain or not. The main goal was to see if drainage lowered pelvic s…
Phase 3 • Sponsor: University Hospital, Bordeaux • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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New drug shows promise for Long-Term control of esophagus inflammation
Disease control CompletedThis study looks at the long-term safety of a drug called CC-93538 (cendakimab) for people with eosinophilic esophagitis, a condition that causes inflammation in the esophagus. It enrolled 367 adults and teens who had already taken part in earlier studies of the same drug. The ma…
Phase 3 • Sponsor: Celgene • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Can a pill stop Cancer's return? new trial targets hidden DNA signals
Disease control CompletedThis Phase 3 study tested the drug FTD/TPI (a chemotherapy pill) against a placebo in 243 people who had surgery for colorectal cancer but still had cancer DNA in their blood. The goal was to see if the drug could prevent the cancer from coming back. Participants took the drug or…
Phase 3 • Sponsor: National Cancer Center Hospital East • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Simple drug may cut infection risk after major gut surgery
Disease control CompletedThis study tested whether tranexamic acid, a drug that helps blood clot, can lower the chance of infection after gastrointestinal surgery. Over 3,300 adults at higher risk for complications took part. The goal was to see if the drug reduces surgical site infections compared to a …
Phase 4 • Sponsor: Bayside Health • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Could a growth hormone help people with End-Stage liver disease?
Disease control CompletedThis study tested whether giving growth hormone to people with decompensated liver cirrhosis (advanced liver scarring) could improve their health and survival. The trial included 96 adults with this condition. Researchers measured how long patients survived without major complica…
Phase 2/3 • Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Baby formula with probiotics may improve poop regularity in infants
Disease control CompletedThis study tested whether a special infant formula containing probiotics and hydrolyzed whey protein can improve gut health in newborns. 240 healthy, full-term infants were assigned to receive either the test formula, a standard formula, or breast milk for 12 months. The main goa…
Sponsor: Heilongjiang Feihe Dairy Co. Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Rare gut condition: which surgery works best?
Disease control CompletedThis study compares two surgeries—One Anastomosis Gastric Bypass and Duodenojejunostomy—for treating Superior Mesenteric Artery Syndrome (SMAS), a rare condition where the duodenum is compressed, causing severe nausea, vomiting, and weight loss. Twenty participants were randomly …
Sponsor: Ain Shams University • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Psoriasis drug OTEZLA tested in everyday use
Disease control CompletedThis completed study observed over 1,000 people with psoriasis who were prescribed OTEZLA (apremilast) for the first time. Researchers tracked side effects, symptom improvement, and quality of life over several years. The goal was to see how well the drug works in real-world sett…
Sponsor: Amgen • Aim: Disease control
Last updated Jun 26, 2026 14:49 UTC
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Handwashing lessons keep kids in school, study finds
Prevention CompletedThis study tested whether teaching hand and respiratory hygiene to primary school children could lower how often they get sick and miss school. Over 800 students in Erbil, Iraq, took part. Some schools got hygiene lessons and reminders, while others did not. The goal was to see i…
Sponsor: Hawler Medical University • Aim: Prevention
Last updated Jun 27, 2026 11:00 UTC
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Could a daily sachet ease your IBS? new trial tests skal pro
Symptom relief CompletedThis study tests whether a daily dose of Skal Pro—a mix of a friendly bacteria (Lactobacillus plantarum 299v) and a prebiotic fiber—can reduce IBS symptoms like belly pain, bloating, and irregular bowel movements. Sixty adults with IBS will receive either the supplement or a dumm…
Phase 4 • Sponsor: EP Plus Group Sdn Bhd • Aim: Symptom relief
Last updated Sep 13, 2026 00:00 UTC
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Could a gummy boost your gut, glow, and Get-Up-and-Go?
Symptom relief CompletedThis trial is testing whether a daily dietary supplement called MultiMineral 102 Gummies can improve digestive health, energy levels, and skin health. About 35 adults who have recently experienced issues in all three areas will take two gummies each morning for 8 weeks. Participa…
Sponsor: Clean Nutraceuticals • Aim: Symptom relief
Last updated Aug 16, 2026 00:00 UTC
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New probiotic aims to soothe tummy troubles in overweight adults
Symptom relief CompletedThis study is testing a new probiotic called CLB101TM in healthy but overweight adults who have digestive issues like bloating or stomach pain. The probiotic is designed to produce a natural substance called butyrate, which may help strengthen the gut lining and support immune he…
Sponsor: ClostraBio Inc. • Aim: Symptom relief
Last updated Aug 15, 2026 00:00 UTC
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Could a phone app help parents of kids with special needs thrive?
Symptom relief CompletedThis trial tests a 12-week smartphone-based program called PACT, which combines acceptance and commitment training with positive parenting advice, for parents of children with special health care needs. The goal is to see if it can improve parents' mental well-being, psychologica…
Sponsor: Chinese University of Hong Kong • Aim: Symptom relief
Last updated Aug 13, 2026 00:00 UTC
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Gut check: do GI supplements really work? new Placebo-Controlled trial seeks answers
Symptom relief CompletedThis study tests two dietary supplements against a placebo to see if they can reduce belly pain, gas, and bloating in adults. Over 800 participants across the U.S. will take the product daily for 6 weeks without knowing which group they are in. The goal is to find out whether the…
Sponsor: Radicle Science • Aim: Symptom relief
Last updated Jul 24, 2026 00:00 UTC
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Could a postbiotic soothe irritable bowel syndrome?
Symptom relief CompletedThis study tests whether a daily postbiotic supplement called PosBion® can ease symptoms and improve quality of life in adults with irritable bowel syndrome (IBS). Participants take two sachets of the supplement each day for 12 weeks. Researchers measure changes in IBS symptoms, …
Sponsor: My Myracle Sdn.Bhd • Aim: Symptom relief
Last updated Jul 16, 2026 00:00 UTC
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Birth control pill side effects? new supplement trial aims to boost mood and energy
Symptom relief CompletedThis Phase 2 trial is testing whether a daily supplement called Alii can reduce common side effects of hormonal birth control pills, like low energy, mood swings, and poor digestive health. Researchers will compare the supplement to a placebo in 68 women over 28 days. Participant…
Phase 2 • Sponsor: Texas Christian University • Aim: Symptom relief
Last updated Jul 15, 2026 00:00 UTC
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Can an online wellness program ease anxiety in chronic disease?
Symptom relief CompletedThis study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…
Sponsor: University of Alberta • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Enzyme pill takes on Post-Meal bloating in new trial
Symptom relief CompletedThis study tested a digestive enzyme supplement in 24 healthy adults to see if it helps break down fats, proteins, and carbs after a high-macronutrient meal. Participants took either the enzyme blend or a placebo and reported symptoms like bloating and gas. The goal is to find a …
Phase 2 • Sponsor: Pancap Pharma Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Which diet soothes stomach pain better? new study tests two options
Symptom relief CompletedThis study looked at 60 people with a common stomach condition called functional dyspepsia, which causes pain and fullness after meals. Participants were split into two groups: one followed standard advice (small meals, avoid fatty/spicy foods), and the other tried a low FODMAP d…
Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Collagen peptide study targets tummy troubles
Symptom relief CompletedThis study tested whether taking collagen peptides daily can reduce stomach discomfort in healthy adults who have mild digestive symptoms. Over 100 participants took either a collagen supplement or a placebo for a period of time. The main goal was to see if the supplement improve…
Sponsor: Rousselot BVBA • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Can a special diet soothe tummy troubles in kids with IBS?
Symptom relief CompletedThis study tested whether a low FODMAP diet (limiting certain carbs) can reduce stomach pain and bloating in children with irritable bowel syndrome (IBS). Seventy children aged 4–18 followed either a low or standard FODMAP diet for two weeks, then switched after a break. Research…
Sponsor: University of Bari • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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New pill may calm diabetic stomach troubles
Symptom relief CompletedThis study tested an experimental drug called CIN-102 (deudomperidone) to see if it can reduce nausea, vomiting, and other stomach symptoms in adults with diabetic gastroparesis—a condition where the stomach empties too slowly. About 382 participants took either the drug or a pla…
Phase 2 • Sponsor: CinDome Pharma, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Can a smartphone app soothe Children's tummy troubles?
Symptom relief CompletedThis pilot study tested whether a guided imagery therapy mobile app could help children aged 7 to 12 with chronic abdominal pain. Four children listened to 10-15 minute recorded sessions five days a week for eight weeks. The study compared immediate app use to a delayed start gro…
Sponsor: Baylor College of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Ear zap device shows promise for teen nausea
Symptom relief CompletedThis study tested a non-invasive nerve stimulator placed on the outer ear to see if it could reduce nausea in 109 teenagers with functional gastrointestinal disorders. Half received the active device, half a sham (inactive) version, for four weeks. The goal was to measure changes…
Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Hypnosis for your stomach? tiny study tests Gut-Directed therapy online
Symptom relief CompletedThis study tested whether gut-directed hypnotherapy (GDH) delivered via telehealth could help manage gastrointestinal symptoms in adults with disorders of gut-brain interaction. Eleven participants completed sessions of general relaxation hypnosis and GDH, plus a 3-month follow-u…
Sponsor: University of Central Florida • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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4,600 people test gut health products in landmark study
Symptom relief CompletedThis study tested whether certain health and wellness products can improve common stomach issues like pain, bloating, constipation, and diarrhea. Over 4,600 adults in the U.S. who wanted better digestion took part. Participants were randomly assigned to receive either the product…
Sponsor: Radicle Science • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Early palliative care may boost quality of life in advanced GI cancers
Symptom relief CompletedThis study looked at whether early contact with a palliative care unit improves quality of life for people with advanced cancers of the upper gastrointestinal tract or colorectal cancer. 108 participants were randomly assigned to either early palliative care or standard care (con…
Sponsor: Lund University Hospital • Aim: Symptom relief
Last updated Jun 26, 2026 16:42 UTC
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50,000 iranians join quest to uncover esophageal cancer triggers
Knowledge-focused CompletedThis completed study enrolled over 50,000 adults aged 40-75 in Iran's Golestan Province to understand why esophageal cancer is so common there. Participants filled out lifestyle and diet questionnaires and provided blood, urine, hair, and nail samples. Researchers are analyzing f…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Can software make hospital pharmacists faster and safer?
Knowledge-focused CompletedThis study tests whether a software tool called Synapse Medicine can help hospital pharmacists who work with medical teams make better and faster medication recommendations. The tool analyzes each patient's health information to flag potential drug-related risks, such as harmful …
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Sep 05, 2026 00:00 UTC
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Could gut microbes hold clues to autism symptoms?
Knowledge-focused CompletedThis study looks at how the gut microbiome and its chemical byproducts relate to gastrointestinal and behavioral symptoms in children with autism. By tracking 23 participants over time, researchers hope to identify biological markers that could one day help manage these symptoms.…
Sponsor: The Center for Discovery • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC
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NICU feeding study questions if 'Full Feed' means 'Full Skill'
Knowledge-focused CompletedThis study reviews the feeding skills of 100 infants discharged from a neonatal intensive care unit (NICU). Researchers want to know if an infant's ability to eat a full amount by mouth means they have fully developed feeding skills. They use a special tool called the SMART Tool …
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Aug 05, 2026 00:00 UTC
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Heartburn pill may mess with your protein absorption
Knowledge-focused CompletedThis pilot study tests whether omeprazole, a common heartburn drug, changes how well the body absorbs protein from food. Four healthy adults aged 50-60 will eat a standard meal with and without the drug, and researchers will measure amino acid levels in their blood. The goal is t…
Sponsor: McGill University • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC
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Blood tests may replace scopes for EoE diagnosis
Knowledge-focused CompletedThis study enrolled 800 adults undergoing upper endoscopy to find risk factors and blood markers that could help diagnose and monitor eosinophilic esophagitis (EoE), a chronic allergic condition of the esophagus. Researchers compared people with and without EoE, collecting blood,…
Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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AI takes on medical paperwork: can it code better than humans?
Knowledge-focused CompletedThis completed trial tested whether an AI system called Easy-ICD helps clinical coders assign ICD-10 codes to medical notes more quickly and accurately. Fifteen healthcare professionals coded 20 clinical notes both with and without the AI tool. The goal was to see if AI can reduc…
Sponsor: University Hospital of North Norway • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Childhood stomach pain: new study tracks Long-Term outcomes
Knowledge-focused CompletedThis study followed 400 children who had stomach pain for at least two months to see how they were doing years later. Researchers used questionnaires to check if they still had symptoms and to identify risk factors for ongoing problems. The goal is to better understand the long-t…
Sponsor: Umeå University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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Sugar and stress: could fructose malabsorption fuel anxiety?
Knowledge-focused CompletedThis study looked at whether difficulty digesting fructose (a sugar found in many foods) is linked to anxiety and changes in gut bacteria. Researchers compared 56 healthy young men who either absorb fructose normally or have trouble absorbing it. The goal was to see if fructose m…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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App vs. phone: which triage method guides patients better?
Knowledge-focused CompletedThis study tested whether a digital symptom checker could work as well as a traditional phone call for guiding patients to the right level of care. Researchers planned to include 120 adults from a primary care center, but only 22 took part. The main goal was to see if a larger tr…
Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Yogurt study probes how friendly bacteria survive the gut
Knowledge-focused CompletedThis study looked at whether eating fermented dairy products with three types of Bifidobacterium (with or without prebiotic fibers) for 28 days changes the variety of gut bacteria in healthy people aged 45 to 60. 182 participants ate either a test yogurt or a regular yogurt. The …
Sponsor: Danone Global Research & Innovation Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Study uncovers gut inflammation link in sick kids
Knowledge-focused CompletedThis study looked at why many critically ill children develop gut problems like slow digestion and leaky gut. Researchers measured certain proteins linked to inflammation in 99 children to see if they cause these issues. The goal was to better understand the problem, not to test …
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Gut health booster? new study puts postbiotic to the test
Knowledge-focused CompletedThis study tested a postbiotic supplement in 76 healthy adults to see if it improves gut bacteria, digestion, stress, and other health markers. Participants took the supplement or a placebo for 4 weeks. The goal was to gather data on how the supplement affects the body, not to tr…
Sponsor: Verb Biotics LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Hidden gut troubles in Sjögren's patients revealed
Knowledge-focused CompletedThis study looked at how often people with primary Sjögren's syndrome have digestive issues. Researchers asked 151 patients about 10 different digestive symptoms using a simple questionnaire. The goal was to understand which symptoms are most common and how they relate to how lon…
Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Biomarkers may guide personalized pain relief for kids
Knowledge-focused CompletedThis study looked at 163 children aged 7-12 with chronic abdominal pain to see if simple tests (biomarkers) could predict whether they would benefit more from cognitive behavioral therapy (CBT) or a low FODMAP diet. The goal was to personalize treatment and improve symptoms and q…
Sponsor: Baylor College of Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Jaundice in babies linked to gut troubles, new study finds
Knowledge-focused CompletedThis study looked at over 3,200 newborns with jaundice to find out which ones were more likely to develop digestive problems like feeding issues or stomach bleeding. Researchers reviewed medical records and used special methods to identify risk factors. The goal is to help doctor…
Sponsor: The First Hospital of Jilin University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Computer aid boosts Kids' gut diagnosis
Knowledge-focused CompletedThis study tested a computer program that helps doctors diagnose common stomach and bowel problems in children. 33 children and their doctors took part. The goal was to see if the tool leads to more accurate diagnoses and better care.
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Which scope spots more gut problems? new study investigates
Knowledge-focused CompletedThis study looked at whether using a forward-viewing scope during a procedure called ERCP helps doctors find more important gut problems than the usual side-viewing scope. 163 adults who needed ERCP had two back-to-back exams with different scopes. The goal was to see how often t…
Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Healthy volunteers needed to donate stool for gut research
Knowledge-focused CompletedThis study collected stool samples from 110 healthy adults aged 18-60 to help Danone advance its research on digestive health. Participants had to have regular bowel movements and be in good health. No treatment or medication was given; the goal was simply to gather enough usable…
Sponsor: Danone Global Research & Innovation Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Could a special diet help IBS patients with flexible joints?
Knowledge-focused CompletedThis study looked at nearly 500 people with stomach and bowel problems to see if a low-FODMAP diet helps reduce symptoms. Researchers also checked for joint hypermobility (very flexible joints) and how the gut microbiome might be linked. The goal is to better understand who benef…
Sponsor: University of Zurich • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Facemasks tested for safety in endoscopy procedures
Knowledge-focused CompletedThis study looked at whether wearing a special facemask during upper endoscopy (a procedure to examine the stomach and esophagus) can reduce the spread of tiny particles into the air. The goal was to better understand infection risks, like COVID-19, for healthcare workers. Resear…
Sponsor: Anthony Lembo • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Gut feeling measured: new device tracks digestive electrical activity
Knowledge-focused CompletedThis study tested a device that records the electrical signals naturally produced by the stomach, small intestine, and colon. Researchers compared readings from 88 people with and without irritable bowel syndrome (IBS) or other gut issues. The goal was to see if the device could …
Sponsor: G-Tech Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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IBD study reveals link between meal regularity and Well-Being
Knowledge-focused CompletedThis study looked at how nutrition, meal patterns, and diet affect quality of life, gut symptoms, and mood in 50 people with inflammatory bowel disease (IBD). Researchers collected data using food recalls and questionnaires. The goal was to better understand the role of diet in m…
Sponsor: Istinye University • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:54 UTC
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Oat fiber supplement shows promise for digestion and blood sugar control
Knowledge-focused CompletedThis completed study looked at how well healthy adults tolerate different doses of an oat fiber supplement called BG-OS. Sixty participants took either 5, 10, or 20 grams daily for several weeks. Researchers tracked digestive symptoms, blood sugar levels after eating white rice, …
Sponsor: One Bio Inc. • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:25 UTC