University Of Missouri-columbia

This study tested whether a medication called amiloride could improve the health and flexibility of blood vessels in overweight adults with insulin resistance. It involved 137 men and women, aged 30-70, who were randomly assigned to receive either amiloride or a placebo pill for …

This project worked with the Cherokee community to adapt and test a culturally relevant program aimed at preventing heart disease. In the second phase, 42 adult Cherokee citizens participated in an intervention designed to strengthen community connection and historical knowledge.…

This study tested a new system to prevent opioid overdose deaths by training everyday citizens to help. Researchers used a smartphone app to alert nearby volunteers when someone was overdosing, so they could quickly deliver the life-saving drug naloxone. The goal was to see if th…

This study tested a new type of rehabilitation therapy for people recovering from a recent stroke. It compared a 'metacognitive strategy training' approach, which teaches problem-solving skills for daily tasks, against standard occupational therapy. The goal was to see if this th…

This study tested if giving a single dose of the medication pregabalin right before kidney stone surgery could help control pain afterward. The goal was to see if this approach could reduce how much opioid pain medication patients needed to take. About 118 adults having this spec…

This study tested whether a remote coaching program could help people with Long COVID manage thinking problems like memory loss and poor focus. Researchers worked with 65 adults who had persistent cognitive symptoms after COVID-19 to see if teaching them specific mental strategie…

This study tested whether a non-drug sleep therapy could reduce pain in women with fibromyalgia. Researchers compared two behavioral sleep programs to see if better sleep could change how the brain processes pain signals. The goal was to see if this relatively brief therapy could…

This study aimed to understand how one night of restricted sleep affects blood flow to the brain the next morning. Researchers compared 16 healthy men and women after a normal night's sleep and after a night of restricted sleep. The goal was to see if sleep loss reduces brain blo…

This study looked at whether Palynziq, a medication that lowers phenylalanine levels in people with PKU, leads to improvements in brain health and thinking skills. Researchers used brain scans and cognitive tests to measure changes in 6 adults with PKU who had been successfully t…

This study aimed to understand if men and women's bodies respond differently to low oxygen levels, specifically how their blood vessels react. Researchers measured blood flow in the arms of 31 healthy young adults while they breathed air with reduced oxygen. The goal was to gathe…