University Of Missouri-columbia

This study planned to test whether a 14-day ketogenic diet before heart bypass surgery could reduce confusion and memory loss in adults aged 60 and older. The diet was thought to lower brain inflammation and improve brain cell health. However, the study was withdrawn before any p…

This study tests whether giving a mix of three drugs (methadone, dexmedetomidine, and ketamine) during complex spine surgery can lower pain and reduce the need for opioid painkillers afterward. About 248 adults aged 18-79 having surgery on three or more spine levels will take par…

This study compares remote monitoring to standard in-person follow-up for adults who had wrist fracture surgery. About 160 participants will use a secure app or attend clinic visits. Researchers will measure arm function, quality of life, and complication rates over 6 months to s…

This study tests an intensive group physical therapy program for children aged 7-17 with cerebral palsy who can walk. The program focuses on improving muscle strength, walking speed, and daily activities like climbing stairs. Researchers will measure changes in strength, balance,…

This study tests whether virtual reality (VR) meditation can improve sleep and reduce anxiety in people with chronic pain and insomnia. About 30 adults with both conditions for at least 6 months will use VR meditation and track their sleep, pain, and mood. The goal is to see if t…

This study tests if giving a standard amount of IV fluids before surgery can prevent low blood pressure after anesthesia in people having a cystoscopy. About 100 adults will take part. The goal is to see if this simple step reduces the risk of blood pressure drops during the proc…

This study looks at why sleep apnea raises the risk of diabetes. Overweight adults with and without sleep apnea will have their blood sugar control measured. Some will receive CPAP, some will get extra oxygen at night, and others will get a sham treatment. The goal is to find out…

This study aimed to see if a mix of telehealth and in-person physical therapy helps children with moderate to severe disability improve their home function better than in-person therapy alone. It planned to include children aged 2-17 and measure changes in daily living skills and…

This early study tests whether sirolimus, an FDA-approved drug, can improve blood flow to the brain in healthy adults with a genetic risk for Alzheimer's disease. Researchers will use MRI scans to measure changes after 4 weeks of daily low-dose sirolimus. The study also explores …

This study looks at how eating pulses like beans, lentils, and chickpeas changes the bacteria in your gut and affects how full you feel after meals. Researchers will give 44 overweight adults a high-pulse diet for 4 weeks and measure changes in gut microbes, appetite hormones, an…

This study looks at how cannabis use affects anesthesia and inflammation in people having lumbar spine surgery. Researchers will compare cannabis users and non-users to see if cannabis changes the amount of anesthesia needed and how the body heals. The goal is to help doctors cre…

This study is testing whether a Mediterranean-style low-carb diet that reduces calories can lower insulin and testosterone levels in overweight or obese women with insulin resistance. Eight premenopausal women aged 21-45 will follow the diet to lose about 5% of their body weight.…

This study looks at whether wearable technology, like the Oura Ring, can help measure stress and burnout in nurses. Fifty nurses from intensive care and surgical units will wear the rings and fill out surveys for 10 weeks. The goal is to see if workload and stress levels are link…

This study looks at how insulin in the brain changes blood flow and nerve signals in healthy adults aged 18-45. Researchers will measure blood flow in the brain and legs, as well as nerve activity. The goal is to understand basic body functions, not to treat any disease.

This study looks at how high-protein drinks affect certain blood cells (monocytes and platelets) that may play a role in heart disease. Ten healthy adults will drink either a low-protein, high-protein, or leucine-added meal, and researchers will check their blood for changes in c…

This study looks at why some people with obesity have normal blood sugar while others do not. Researchers will measure how much sugar fat and muscle tissues take up in people with and without insulin resistance. About 90 adults will participate, including lean and obese individua…