University Of Missouri-columbia
Clinical trials sponsored by University Of Missouri-columbia, explained in plain language.
-
Fish oil pills aim to stop Post-Surgery confusion in seniors
Prevention ENROLLING_BY_INVITATIONThis study is testing whether giving omega-3 fatty acid supplements before and after major heart surgery can help prevent postoperative delirium, a common and serious state of confusion, in patients aged 65 and older. Researchers will give 90 participants either 0, 2, or 4 grams …
Phase: PHASE2 • Sponsor: University of Missouri-Columbia • Aim: Prevention
Last updated Mar 31, 2026 12:11 UTC
-
New exercise program aims to boost strength and mobility for kids with cerebral palsy
Symptom relief ENROLLING_BY_INVITATIONThis study is testing a 15-week group exercise program for children with cerebral palsy. The program involves walking, strength training, and balance exercises twice a week, led by physical therapy students under supervision. The main goal is to see if the program improves the ch…
Sponsor: University of Missouri-Columbia • Aim: Symptom relief
Last updated Apr 01, 2026 14:43 UTC
-
Simple IV fluid push could stop dangerous blood pressure drops in common surgery
Symptom relief ENROLLING_BY_INVITATIONThis study is testing whether giving a bag of IV fluids right before a common bladder scope procedure can prevent a dangerous drop in blood pressure when anesthesia begins. Researchers will compare 100 adults having elective cystoscopies, with half receiving the extra fluids. The…
Phase: PHASE4 • Sponsor: University of Missouri-Columbia • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
-
Could telehealth boost therapy for kids with disabilities at home?
Symptom relief TerminatedThis study aimed to see if combining telehealth video calls with in-person physical therapy sessions works better than in-person therapy alone for improving daily living skills at home for children with moderate to severe disabilities. It planned to involve children aged 2-17 and…
Phase: NA • Sponsor: University of Missouri-Columbia • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
-
Back surgery drug battle: which one lets you pee?
Symptom relief ENROLLING_BY_INVITATIONThis study compares two different drug combinations given to patients after outpatient back surgery. The goal is to see which one is better at preventing a painful condition called urinary retention, where patients can't urinate after surgery. Researchers will measure how many pa…
Phase: PHASE4 • Sponsor: University of Missouri-Columbia • Aim: Symptom relief
Last updated Mar 11, 2026 14:54 UTC
-
Can an 8-Week diet tame hormones linked to weight gain?
Knowledge-focused OngoingThis study aims to understand how a specific diet and weight loss affect key hormones in women. Researchers are testing if an 8-week Mediterranean-style diet, designed to help participants lose 5% of their body weight, lowers insulin and testosterone levels. The study involves wo…
Phase: NA • Sponsor: University of Missouri-Columbia • Aim: Knowledge-focused
Last updated Apr 01, 2026 21:56 UTC
-
Can a bean diet tame your appetite and reshape your gut?
Knowledge-focused OngoingThis study aims to understand how eating beans (like lentils and chickpeas) affects the bacteria in your gut and how full you feel after meals. Researchers are comparing a diet with beans to one without beans in 44 overweight adults. They will measure changes in gut bacteria, app…
Phase: NA • Sponsor: University of Missouri-Columbia • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
-
Could a common drug unlock Alzheimer's prevention by boosting brain blood flow?
Knowledge-focused OngoingThis early-stage study is investigating whether sirolimus, an FDA-approved medication, can improve blood flow to the brain in healthy adults who carry a genetic risk for Alzheimer's disease. Researchers are using MRI scans to measure changes in brain blood flow and, in a second p…
Phase: PHASE1 • Sponsor: University of Missouri-Columbia • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:01 UTC
-
Could your cannabis habit change your surgery? new study investigates
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to understand how a person's cannabis use affects the amount of anesthesia they need during back surgery and their recovery afterward. Researchers will observe 210 adults having lower back surgery, comparing those who use cannabis to those who don't. They will tra…
Sponsor: University of Missouri-Columbia • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:17 UTC
-
Smart rings track Nurses' stress to fight burnout
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to understand how nurses' workload affects their stress levels and overall health. Researchers will track 50 nurses from intensive care and medical-surgical units using smart rings to monitor heart rate and sleep, combined with shift data and surveys. The goal is …
Sponsor: University of Missouri-Columbia • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC
-
Scientists probe Brain's response to insulin in Early-Stage research
Knowledge-focused TerminatedThis early research study aims to understand how insulin affects blood flow to the brain and nervous system activity in healthy adults. Researchers will measure brain and leg blood flow, as well as nerve signals, in 65 participants aged 18-45. The study is currently suspended and…
Phase: EARLY_PHASE1 • Sponsor: University of Missouri-Columbia • Aim: Knowledge-focused
Last updated Mar 17, 2026 13:09 UTC