Cure My Disease

Don't miss your cure!

 Log in / Sign up

Study reveals cannabis users may need more anesthesia during spine surgery

NCT ID NCT07354412

Knowledge-focused Sponsor: University of Missouri-Columbia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how different patterns of cannabis use (like how often, how long, and what type) affect anesthesia needs and inflammation in people having lumbar spine surgery. Researchers will measure the amount of anesthesia and pain medication needed during surgery, as well as inflammatory markers in the blood before and after surgery. The goal is to better understand how cannabis use impacts surgical care and recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
cannabis (various THC:CBD ratios, routes, frequency, duration)
What this could lead to
If successful, this could lead to personalized anesthesia protocols that account for cannabis use, improving safety and pain management during surgery.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly change care yet. Results may vary due to the wide range of cannabis use patterns.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 210 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Ambulatory and short-stay lumbar spine surgery patients

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria for both cannabis users and non-users: * Undergoing ambulatory or short-stay lumbar spine surgery. * English speaking. * Ability to consent for themselves. * Aged 18 years and above. * Access to a smartphone or computer/laptop (to be determined on the day of consent). Inclusion criteria for cannabis users: • Any lifetime use of cannabis products irrespective of the strain, CBD/THC content, or frequency of use. Exclusion Criteria: * Non-English speaking. * Inability to consent for themselves. * Actively pregnant (SOC) or planning to become pregnant in the next 2 months (research only). Urine testing will be done as SOC prior to undergoing surgery. * Active or past severe psychiatric instability (e.g., active psychosis, acute suicidality) * Active, uncontrolled use of illicit drugs use such as methamphetamine, cocaine, opioids, etc., as listed in their clinical charts. * History of major neurological illnesses. * Presence of an untreated illness or serious medical condition. * Any other concern that in the investigator's opinion would impact participant safety, study instruction compliance, or confound the interpretation of the study results. * No access to a smartphone or computer/laptop.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Cannabis use are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cannabis dependence Inflammation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cannabis use

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Missouri Orthopaedic Institute

    Columbia, Missouri, 65211, United States

  • University Hospital

    Columbia, Missouri, 65212, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.