Can a Low-Carb diet tame insulin and testosterone in overweight women?

NCT ID NCT06998238

Ongoing Knowledge-focused Sponsor: University of Missouri-Columbia Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a Mediterranean-style low-carb diet that reduces calories can lower insulin and testosterone levels in overweight or obese women with insulin resistance. Eight premenopausal women aged 21-45 will follow the diet to lose about 5% of their body weight. Researchers will measure changes in fasting hormones and insulin sensitivity to understand how weight loss affects these factors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Mediterranean-based, carbohydrate-restricted, calorie-reduced diet
What this could lead to: If successful, this study could clarify how weight loss affects insulin and testosterone levels in women with insulin resistance.
What could go wrong: This is a very small early-stage study with only 8 participants, so results may not apply to the broader population.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HYPERANDROGENEMIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Insulin Resistance Obesity obesity disorder Overweight polycystic ovary syndrome Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERANDROGENEMIA INSULIN RESISTANCE OVERWEIGHT AND OBESITY

Contacts and locations

Locations

University of Missouri

Columbia, Missouri, 65211, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.