University Of Minnesota

This study tested whether three common, inexpensive drugs—metformin, ivermectin, and fluvoxamine—could prevent severe illness in 1,323 adults with early COVID-19. Participants were not hospitalized and had a higher body weight, which increases risk. The key finding was that metfo…

This early-phase study tested whether having a family member or friend as a 'Follower' who can see real-time glucose data, plus a personalized action plan, helps adults with type 1 diabetes avoid severe high blood sugar that can lead to diabetic ketoacidosis (DKA). 22 adults at h…

This early study tested whether a thin, clear membrane from the back of the cornea (Descemet's membrane) can help the eye heal in people with limbal stem cell deficiency, a condition that causes blindness. Nineteen participants received the membrane as a patch on the eye's surfac…

This study compared a full-mouth electronic toothbrush to a conventional electric toothbrush in 94 adults with mild to moderate gingivitis. Researchers measured gum inflammation and plaque buildup to see if the new brush performed better. The goal is to improve daily oral care an…

This study tested whether taking fecal microbiota transplant (FMT) capsules could help prevent Crohn's disease from returning after surgery. 23 adults who had surgery for Crohn's received FMT either by capsules or colonoscopy. Researchers checked if the good bacteria from the don…

This study tested a support program for 95 caregivers of family members who have both traumatic brain injury (TBI) and dementia. The program included education and counseling to help caregivers cope with stress and communicate better. The goal was to reduce caregiver burden and i…

This study tested whether the drug brivaracetam can reduce nerve pain in people with long-term spinal cord injury. 44 adults with chronic pain took either the drug or a placebo for 7 weeks. Researchers measured changes in pain intensity and how it affected daily life, mood, and s…

This study tested whether the drug brivaracetam can reduce severe nerve pain in people with chronic spinal cord injury. 24 participants received either the drug or a placebo for 3 months. The goal was to see if the drug is feasible and helps with pain and quality of life.

This pilot study looked at whether adding a mild electrical brain stimulation (tDCS) to intensive speech therapy can improve language skills in people with non-fluent aphasia after a stroke. Ten adults completed both real and sham stimulation sessions over two weeks. The goal was…

This pilot study tested whether offering free legal services to people with advanced colorectal cancer could reduce stress and financial worries. Twenty participants received personalized legal help from a nonprofit organization for six months. Researchers measured changes in str…

This study tested whether special breathing exercises could help people with Long COVID who have trouble breathing and feel tired. Sixteen adults who had COVID-19 at least 4 weeks earlier and still had symptoms like shortness of breath or chest tightness took part. They did diaph…

This study tested a program called Link for Equity in 12 Minnesota middle and high schools. The program trains school staff to be more aware of racism and its impact, aiming to reduce bullying, fights, and unfair discipline for students of color. About 518 students of color took …

This study looked at whether a specific 8-week exercise program can improve thumb joint alignment in people with thumb arthritis. It also tested if ultrasound can measure joint movement as accurately as a CT scan. 21 adults with thumb arthritis participated. The goal was to learn…

This study used a non-invasive technique called transcranial magnetic stimulation (TMS) to measure brain activity in 24 people who had a stroke at least 6 months earlier. Researchers wanted to see how stroke changes the brain's motor signals and how natural brain rhythms affect t…

This study looked at how bacteria grow in the nose, mouth, and lungs of 7 infants with cystic fibrosis during their first year of life. Researchers collected swabs and mucus samples to map bacterial communities. The goal was to understand how germs move through the airway, which …

This study tested two ways of training long-term care workers (nurses, managers, and staff) to provide better care for LGBTQ+ people with Alzheimer's or other dementias. Over 760 participants from Minnesota took part in either an in-person or online training program. The goal was…

This study looked at whether a continuous glucose monitor (CGM) can help predict low blood sugar (hypoglycemia) in adults with type 2 diabetes. 41 participants wore either a CGM that showed their glucose levels or a hidden one. Researchers compared how often low blood sugar occur…

This study looked at lungs removed from 74 people with cystic fibrosis during transplant surgery. Researchers wanted to see if different areas of the lung have different types of bacteria and chemical environments. By mapping these differences, they hope to find new ways to treat…

This study created a registry of 655 people and families with Alport syndrome, a genetic kidney disease. Researchers collected health information over time to better understand the disease. The goal was to build a foundation for future studies that could test potential treatments…

This study tested a program to help adult men in prison who have committed child sexual abuse avoid doing it again. Ten men participated, and researchers measured changes in risk factors like coping skills and attitudes. The goal was to see if the program could be used in a large…

This study tested a program called Link for Equity, which trains school staff to be more aware of racism and trauma. Over 1,600 staff from 12 secondary schools in Minnesota took part. The goal was to see if this training could help reduce differences in school violence and discip…

This study looked at whether a home body water analyzer can help detect lymphedema early in breast cancer survivors. Lymphedema is swelling caused by fluid buildup after cancer treatment, and catching it early is key because early stages are reversible. 52 women used the device a…

This study tested a new program to help Somali families reduce shisha (hookah) smoke inside their homes. Fifteen families took part, and researchers checked if the program was easy to use and if it lowered smoke exposure by testing urine and saliva. The goal was to see if this ap…

This study looked at levels of certain brain chemicals linked to oxidative stress and inflammation in people with Type 1 Gaucher disease and healthy volunteers. Researchers used brain scans to measure these chemicals over time. The goal was to understand how Gaucher disease affec…

This study tested an online parenting training program called GenerationPMTO to help prevent behavior problems in children. Researchers worked with 94 parents and primary care providers to see if the program was easy to access and use. The goal was to make parenting support more …