Could a seizure drug ease unbearable nerve pain in spinal cord injury?
NCT ID NCT04379011
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tested whether brivaracetam, a drug used for seizures, can reduce severe nerve pain in people with chronic spinal cord injury. 24 participants received either brivaracetam or a placebo for 3 months. The study aimed to see if a larger trial is possible and measured pain levels and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Brivaracetam (Briviact)
What this could lead to
If it works, this could point toward a new treatment option for severe nerve pain after spinal cord injury that hasn't responded to other drugs.
What could go wrong
This is a very small pilot study (24 people) focused on feasibility, not proof of effectiveness. The results may not apply to everyone, and side effects or lack of pain relief are possible.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Swedish Hospital
Englewood, Colorado, 80113, United States
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University of Minnesota School of Medicine
Minneapolis, Minnesota, 55455, United States